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11 Mar 2020 | 03:58 PM (IST)
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Domi UP 2mg Injection


Overview

Introduction

Domi UP 2mg Injection is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Domi UP 2mg Injection will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you appropriate dose depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections. 

The most common side effects of taking this medicine include injection site pain, headache and constipation. These symptoms should disappear when you stop taking the medicine.  But, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

Uses of Domi UP Injection

Side effects of Domi UP Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Domi UP

  • Headache
  • Constipation
  • Injection site pain

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.
  • Coping with Injection site pain
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.

How to use Domi UP Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Domi UP Injection works

Domi UP 2mg Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Domi UP 2mg Injection does not cause any harmful side effects.
Pregnancy
SAFE IF PRESCRIBED
Domi UP 2mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Domi UP 2mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Domi UP 2mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Domi UP 2mg Injection is safe to use in patients with kidney disease. No dose adjustment of Domi UP 2mg Injection is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Domi UP 2mg Injection in patients with liver disease. Please consult your doctor.

What if you forget to take Domi UP Injection?

If you miss a dose of Domi UP 2mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Domi UP 2mg Injection
₹5.9/ml of Injection
Vomikind Injection
Mankind Pharma Ltd
₹3.38/ml of Injection
save 43%
Vomikind Injection
Mankind Pharma Ltd
₹6.4/ml of Injection
8% costlier
Ondem Injection
Alkem Laboratories Ltd
₹6.4/ml of Injection
8% costlier
Periset Injection
Ipca Laboratories Ltd
₹6.41/ml of Injection
9% costlier
Doran-O 2mg Injection
BestoChem Formulations India Ltd
₹7.35/ml of Injection
25% costlier

Quick Tips

  • You have been prescribed Domi UP 2mg Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
  • Unlike some other nausea medicines, the side effects for Domi UP 2mg Injection are relatively mild.
  • It is given as an injection into veins or as drip under the supervision of a doctor.
  • Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.
  • It may cause an application site reaction like redness, swelling, and pain. Consult with your doctor if it bothers you.

Interaction with Drugs

Taking Domi UP with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Acicod, Montokuf, Codine Sulphate
SERIOUS
Brand(s): Parvodex
SERIOUS
Brand(s): Nalfy, Nacphin, Ruffy
SERIOUS
Brand(s): Wintal
SERIOUS

Patient Concerns

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Have done vomiting 3-4 times after wake up The teeth feeling like acidic while vomiting
Dr. Pushkar Mani
Physician
take injection Ondem 4mg 1 vial
Pregnant women Feeling nausea, vomiting and stomach ache. Third month of pregnancy. Doctor is giving pyridoxine and doxylamine succinate from first month. But relief is not up to the mark.
Dr. Suman Rao
Obstetrics and Gynaecology
This is the safest tab for vomiting during pregnancy.
arrow
Do you have any questions related to Domi UP 2mg Injection ?

FAQs

Q. How quickly does Domi UP work?

Domi UP starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

Q. What are the side effects of Domi UP?

The most common side effects of Domi UP are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

Q. Is Domi UP a steroid?

No, Domi UP is an antiemetic and not a steroid. Domi UP is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Q. Does Domi UP work for seasickness?

No, Domi UP does not work for seasickness. This is because Domi UP has very little effect on the nausea associated with motion sickness.

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
  2. Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
  3. MedlinePlus. Ondansetron. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

LINCOLN HOUSE, B/h. Satyam Complex, Science City Road, Sola, Ahmedabad – 380 062., Gujarat, India,
A licensed vendor partner from your nearest location will deliver Domi UP 2mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP11.8  Get 15% OFF
Best Price
₹10.03
Valid only on the orders above ₹500
2 ml in 1 vial
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