Dobustan Injection
Product introduction
Dobustan Injection is a medicine used for short-term treatment of cardiac decompensation (low blood pressure due to poorly functioning heart) due to disease like heart failure, cardiogenic shock, or heart attack. It increases the blood pressure by increasing the pumping capacity of the heart.
Dobustan Injection is also used while performing stress echocardiography evaluation of the heart. It is administered under the supervision of a doctor as it requires continuous blood pressure monitoring. The dose has to be individually adjusted as per the patient's response to therapy. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure.
It may cause side effects like high blood pressure and insomnia (difficulty in sleeping). You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know about all the other medications that you are using regularly.
Uses of Dobustan Injection
- Heart Failure
- Decreased blood pressure
- Low blood pressure
Benefits of Dobustan Injection
In Low blood pressure
Dobustan Injection is used to normalise decreased blood pressure (hypotension) which may occur all of a sudden during an operation, severe infection (sepsis) or due to an emergency condition (cardiac arrest). This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.
Side effects of Dobustan Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dobustan
- High blood pressure
- Insomnia (difficulty in sleeping)
How to use Dobustan Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dobustan Injection works
Dobustan Injection is a sympathomimetic agonist. It works by activating the receptors in the heart. This makes the heart pump blood with more strength and force and increases its pumping capacity in conditions such as heart failure.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dobustan Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Dobustan Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Dobustan Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Dobustan Injection may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Dobustan Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Dobustan Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Dobustan Injection in patients with liver disease. Please consult your doctor.
What if you forget to take Dobustan Injection?
If you miss a dose of Dobustan Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- It is given into the vein as a drip by a healthcare professional.
- Your doctor may perform regular blood tests to monitor the level of sodium and potassium in the blood.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- It is given into the vein as a drip by a healthcare professional.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Fact Box
Chemical Class
Catecholamine Derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Beta-Adrenergic Inotropes
Interaction with drugs
Taking Dobustan with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Metoprolol Succinate may reduce efficacy of Dobutamine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Labetalol may reduce efficacy of Dobutamine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Carvedilol may reduce efficacy of Dobutamine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Nebivolol may reduce efficacy of Dobutamine.
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Atenolol may reduce efficacy of Dobutamine.
Patient concerns
FAQs
What is Dobustan Injection used for?
Dobustan Injection is a drug given through a vein to help the heart pump more effectively when it is not contracting well. It is usually used for short-term support in adults with weakened heart function due to heart disease or after heart surgery.
Who should not receive Dobustan Injection?
Individuals should not receive Dobustan Injection if they have a heart condition called idiopathic hypertrophic subaortic stenosis (a heart condition characterized by thickening of the heart muscle, particularly in the left ventricle, which can obstruct blood flow out of the heart) , or if they are allergic to dobutamine or any ingredient in the drug.
Can Dobustan Injection increase heart rate or blood pressure?
Yes, Dobustan Injection can sometimes cause a significant rise in heart rate or blood pressure, especially in people with high blood pressure. Doctors will closely monitor your heart rate and blood pressure during treatment to adjust the dose if needed.
Is Dobustan Injection safe for people with irregular heartbeats?
If you have atrial fibrillation or other irregular heart rhythms, Dobustan Injection may speed up your heart rate. In such cases, your doctor may modify the treatment regimen before starting Dobustan Injection.
What are the serious side effects of Dobustan Injection?
The serious side effects of Dobustan Injection include severe chest pain, rapid or irregular heartbeat, sudden drop in blood pressure, difficulty breathing, or signs of an allergic reaction such as rash, swelling, or wheezing. Seek immediate medical attention if you experience any of these symptoms.
Can Dobustan Injection cause low potassium levels?
Dobustan Injection may cause a mild drop in blood potassium levels. Your doctor may monitor your potassium during treatment, especially if you are at risk for low potassium.
Can Dobustan Injection be used after a heart attack?
Dobustan Injection is not routinely recommended immediately after a heart attack because it might increase the size of the damaged area in the heart. Your doctor will decide if the benefits outweigh the risks in your case.
How quickly does Dobustan Injection start working?
Dobustan Injection usually begins working within 1 to 2 minutes after starting the infusion , and its peak effect may be seen within about 10 minutes.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Maron BA, Rocco TP. Pharmacotherapy of Congestive Heart Failure. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 804-805.
- Katzung BG, Parmley WW. Drugs Used in Heart Failure. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 216-217.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 421.
- Teerlink JR, Sliwa K, Opie LH. Heart Failure. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 177-81.
- Dobutamine. Hameln, Germany: Siegfried Hameln GmbH; 2018. [Accessed 15 Mar. 2019] (online) Available from:
- Dobutamine. Lake Forest, Illinois: Hospira, Inc.; 2016. [Accessed 15 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dobutamine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Dobutamine. [Accessed 15 Mar. 2019] (online) Available from:
Marketer details
Name: Biogen Serums Pvt Ltd
Address: R6 Sector, A 104, Life Republic Marunji, Hinjewadi - 411057
Country of origin: India
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