Author Details
Written By
BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated:
20 Feb 2020 | 06:32 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Distinon Tablet


Overview

Introduction

Distinon Tablet is a prescription medicine used in the treatment of myasthenia gravis (a disease causing muscle weakness and tiredness), paralytic ileus (paralysis of intestinal muscles), post-operative urinary retention and reversal of effect of skeletal muscle relaxants after surgery.

Distinon Tablet works by reducing and improving muscle weakness. It should be taken on an empty stomach, preferably at the same time each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment. You should never stop this medicine suddenly without talking to your doctor.

Some common side effects of using this medication are nausea, excessive salivation, diarrhea, blurred vision, shortness of breath, watery eyes, abdominal pain and altered frequency of urination. Some other side effects that may be seen with it include sweating, headache, runny nose, and heartburn. It may also cause dizziness and sleepiness. So, avoid doing any such work that requires focus and attention, such as driving or operating any machinery.

Before taking Distinon Tablet, it is better to inform your doctor if you are suffering from any kidney problems, Parkinson's disease, asthma, or stomach disorders. Your blood pressure may decrease after taking this medicine, so it is better to monitor it and consult your doctor if it bothers you. This medicine may cause diarrhea, so drink plenty of fluids to keep yourself hydrated while taking this medicine. Inform your doctor if you are pregnant, planning to conceive or breastfeeding, before taking this medicine.

Uses of Distinon Tablet

Side effects of Distinon Tablet

Common
  • Nausea
  • Excessive salivation
  • Diarrhea
  • Blurred vision
  • Breathlessness
  • Watery eyes
  • Abdominal pain
  • Altered frequency of urination
  • Sweating
  • Headache
  • Dizziness
  • Runny nose
  • Heartburn
  • Gastro-esophageal reflux disease
  • Paresthesia (tingling or pricking sensation)
  • Muscle twitching
  • Weakness
  • Muscle cramp

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Blurred vision
    You can consider washing your eyes with water. Avoid driving or using tools or machines if your vision is impaired. Do not take your next dose if your vision is still blurry. If it gets worse or does not improve, ask your doctor to recommend eye drops or talk about changing your medications.
  • Coping with Breathlessness
    Control your breaths by breathing in slowly through your nose and breathing out through your mouth. Sitting on a chair and leaning your chest slightly forward may also help. Increase the flow of air around you by opening windows or using a fan. Try to learn breathing techniques and do regular physical exercise. Wearing loose clothing around your waist and chest may also be helpful. Your breathing will usually return to normal within a few weeks of starting the medicine. Tell your doctor if your symptoms do not improve or get worse. Shortness of breath can also be a sign of an ongoing or worsening heart problem.
  • Coping with Abdominal pain
    In most cases, this is mild enough to be treated at home. Try to rest and relax. Putting a heat pad or covered hot water bottle on your stomach may also help. Having a warm bath or shower can help you relax and relieve the pain. Drink plenty of clear fluids such as water and reduce your intake of coffee, tea, lemon juice or soda. Avoid alcohol and smoking as these can aggravate the pain. Eating slowly and having smaller and more frequent meals can also help. If the pain is severe, speak to your doctor. They may be able to guide you better.
  • Coping with Sweating
    Try wearing loose, light-weighted, and breathable clothing. Use a strong antiperspirant and keep yourself cool with a fan. Changing your shoes and socks often might also help. Try cutting down on coffee, tea, and alcohol as they can increase your body temperature and promote sweating. Avoid spicy foods, this will help you deal with excessive sweating. If this does not help, talk to your doctor about other possible medications.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Heartburn and Gastro-esophageal reflux disease
    Avoid foods that irritate the stomach such as alcohol, carbonated soft drinks, citrus, coffee, fatty foods or tomatoes. Eat or drink slowly. Eat smaller, more frequent meals. The reason being, large meals fill the stomach and put pressure, causing reflux. Quit smoking if you smoke, lose weight if you are overweight and avoid tight waistbands. Ask your doctor about medicines to treat this condition such as antacids. Do not lie down immediately after eating and wait for at least three hours before lying down after a meal. Raise the head of your bed. Talk to your doctor if your condition does not improve, they may be able to reduce the dosage or switch you to another medicine.
  • Coping with Paresthesia (tingling or pricking sensation)
    Massaging the numb area can help improve blood flow and provide relief. Try warming your hands and feet if they are cold. In case they are hot, try cooling them down. Get plenty of rest as lack of proper sleep may worsen the condition. Reducing stress, avoiding alcohol, exercising regularly, and getting enough vitamins and nutrients through your diet can also make you feel better.
  • Coping with Weakness
    Make sure you rest and drink plenty of fluids. Eat a well-balanced diet to keep your energy levels up. Do not drink too much alcohol. Do not drive or use tools or machinery until you feel better. Other things that can help include doing some gentle exercise every day, prioritizing and pacing your activities and having a short nap if you need to. If you are still having problems after a week, speak to your doctor, as they may want to change you to a different type of medicine.
  • Coping with Muscle cramp
    Tell your doctor straight away because sometimes the muscle pain may be a sign of something more serious. A lower dosage or a different medication might be needed. Try to relax the cramping muscle by stretching it and holding the stretch. You might massage the muscle or apply a heat pad to the area after stretching. Avoid exercising too much. Stay well-hydrated. Do not take over-the-counter pain relievers unless the doctor prescribes it. Your doctor may also suggest taking supplements, such as calcium, magnesium oxide or potassium oxide depending on your needs.

How to use Distinon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Distinon Tablet is to be taken empty stomach.

How Distinon Tablet works

Distinon Tablet increases the levels of acetylcholine (chemical messenger) which allows free transmission of signals across the nerves and muscles.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Distinon Tablet. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Distinon Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Distinon Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Distinon Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Distinon Tablet may reduce the sharpness of your eyesight and therefore your ability to drive or use machines. Do not drive or operate machines if this medicine affects your ability to see clearly.
Kidney
CAUTION
Distinon Tablet should be used with caution in patients with kidney disease. Dose adjustment of Distinon Tablet may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Distinon Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Distinon Tablet?

If you miss a dose of Distinon Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Distinon Tablet
₹8.54/Tablet
Mygris 60mg Tablet
Bharat Serums & Vaccines Ltd
₹7.79/Tablet
save 9%
Mustone 60mg Tablet
Chandra Bhagat Pharma Pvt Ltd
₹7.99/Tablet
save 6%
Pyodistig 60mg Tablet
Intas Pharmaceuticals Ltd
₹13.3/Tablet
56% costlier
Gravitor Tablet
Sun Pharmaceutical Industries Ltd
₹15.9/Tablet
86% costlier
Myestin 60mg Tablet
Vhb Life Sciences Inc
₹16.6/Tablet
94% costlier

Quick Tips

  • You have been prescribed Distinon Tablet for treatment of myasthenia gravis.
  • It may also be used to treat inactivity of the muscle in the intestines (paralytic ileus) and difficulty in passing urine (urinary retention) after an operation.
  • Take it with food to avoid an upset stomach.
  • Take it as per the dose and duration advised by your doctor. Overdosing can result in extreme muscle weakness.
  • It may cause dizziness or blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.
  • Do not drink alcohol while taking this medicine as it may worsen the side effects.
  • Inform your doctor if you have an existing kidney problem, parkinson's disease, asthma, or stomach disorders.

Patient Concerns

arrow
Drooping of eyelids. What is the cause of it? What is the remedy?
Dr. Vishal Maniar
Ophthalmology
At ur age u need detailed eye checkup and neurologist referenceTo rule out myasthenia gravis, ocular palsy Bells palsy,diabetes,trauma
Right medicine for myasthenia gravis
Dr. Vikas Sharma
Neurology
many ; cant advise online as they are strong medicine
arrow
Do you have any questions related to Distinon Tablet ?

User Feedback


FAQs

Q. Does Distinon cure myasthenia gravis? For how long do I need to take it?

Distinon helps reduce and improve muscle weakness and hence relieves the symptoms of myasthenia gravis but does not cure it. The length of time for which you have to take Distinon will depend on your needs. You should not stop taking Distinon until and unless advised by your doctor, even if you start feeling better.

Q. Will Distinon have any effect on my baby if I am breastfeeding?

A very small quantity of Distinon passes into breast milk, which may or may not affect your baby. Ask your doctor if you can continue to breastfeed your baby.

Q. Can I take Distinon for constipation?

No, Distinon should not be taken for any type of constipation. It is used only when constipation occurs due to paralysis of the intestine and strictly on prescription by the doctor.

Q. Who should not take Distinon?

Distinon should not be taken by patients who are allergic to it. It should also be avoided by patients who are constipated or cannot urinate, unless the doctor has advised to use this medicine. This is because Distinon is only used to treat certain types of constipation and inability to pass urine.

Q. What should I do if I have accidentally taken more than the required dose?

You should immediately seek help at a nearby hospital or contact your doctor urgently. An excess dose of Distinon may cause stomach pain, nausea, vomiting, diarrhea, excessive sweating, salivation, blurred vision, excessive weakness, difficulty in breathing and even paralysis.

Q. Is Distinon a steroid?

No, Distinon is not a steroid. It belongs to anticholinesterases group of medicines. Distinon works by preventing the breakdown of a chemical called acetylcholine.

Q. Does Distinon have any abuse potential?

No, there is no evidence that Distinon has abuse potential.

Q. Does it cause weight gain?

No, Distinon does not cause weight gain. If you experience weight gain, it may be due to inactivity related to muscle weakness in myasthenia gravis.

Q. Is Distinon safe to use?

Yes, Distinon is safe if used according to the doctor’s advice. You should not exceed the dose as prescribed by the doctor.

Q. Is it safe to drive if I have taken Distinon?

Distinon may cause blurred vision, and therefore you should limit driving until you know how it affects you.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1172-73.
  2. Drugs.com. Pyridostigmine. (online) [Accessed 22 Mar. 2019] Available from:External Link
  3. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pyridostigmine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:External Link
  4. Pyridostigmine. Hertfordshire, UK: Mylan Products Limited; 1998 [revised 27 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
A licensed vendor partner from your nearest location will deliver Distinon Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Best Price
₹72.59
MRP85.4  Get 15% OFF
This price is valid only on the orders above ₹500
10 tablets in 1 strip
Add To Cart
Estimated delivery between Apr 10 - 12
The order should be placed with a valid prescription

1mg is committed to delivering goods on time in your city, despite the current lockdown.
Delivering to
CHANGE
Additional offers
Paytm: Get up to ₹500 cashback (min cashback ₹50) on your first ever Paytm wallet transaction. Valid only on orders above ₹500. Check your scratch card within 3 days of transaction to avail the offer. Valid till April 15 2020.
Show more show_more

INDIA’S LARGEST HEALTHCARE PLATFORM

150M+
Visitors
25M+
Orders Delivered
1000+
Cities
Get the link to download App
Reliable

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.