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Pyridostigmine

INFORMATION

Uses

Pyridostigmine is used in the treatment of myasthenia gravis (weakness and rapid fatigue of muscles), paralytic ileus (intestinal blockage), post-operative urinary retention and reversal of effect of skeletal muscle relaxant after surgery.

How it works

Pyridostigmine belongs to the group of medicines called parasympathomimetics. It acts by inhibiting the enzyme called as acetylcholinesterase and thus allows free transmission of nerve impulses across the neuromuscular junction.

Common side effects

Pale colored skin, Panic attacks, Rash, Allergic skin rash, Blurred vision, Cold sweat, Confusion, Convulsion, Shortness of breath, Frequent urge to urinate, Itching, Mental impairment, Muscle weakness, Slurred speech, Stomach upset, Urticaria, Watery eyes, Vomiting, Diarrhoea

AVAILABLE MEDICINE

Expert advice

  • Do not start or continue the pyridostigmine medication if you are allergic to pyridostigmine or any other ingredient in the medicine.
  • Do not take pyridostigmine if you have recently had coronary obstruction (heart attack); slow heart beat or any other heart condition; asthma; or stomach ulcer.
  • Avoid taking pyridostigmine if you have fits (epilepsy) or Parkinson’s disease; an overactive thyroid gland; bladder or bowel obstruction.

Frequently asked questions

Pyridostigmine

Q.Is pyridostigmine a narcotic/steroid/ immunosuppressant/ anticholinesterase?
Pyridostigmine is parasympathomimetic and not a narcotic/ steroid/immunosuppressant. It acts by inhibiting the enzyme called as acetylcholinesterase

Q.What is pyridostigmine/ pyridostigmine bromide/pyridostigmine 60 mg is used for?
Pyridostigmine is used to treat neuromuscular disease characterized by very weak muscles and unusual tiredness (myasthenia gravis), paralytic ileus and postoperative urinary retention, reversal of neuromuscular blockade

Q.What class is pyridostigmine?
Pyridostigmine belongs to the group of medicines called parasympathomimetics

Q.Does pyridostigmine cause weight gain?
Pyridostigmine causing weight gain is very rare. However consult your doctor if you experience such side effect

Q.How does pyridostigmine work/ treat myasthenia gravis?
It works by inhibiting the enzyme called as acetylcholinesterase and thus allows free transmission of nerve impulses across the neuromuscular junction.


Content on this page was last updated on 28 September, 2016, by Dr. Varun Gupta (MD Pharmacology)