Diran 50mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 13 Oct 2025 | 04:21 PM (IST)

Diran 50mg Tablet is a pain-relieving medicine. It is used to treat pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is commonly used in back pain, shoulder pain, neck pain, sprains, and spasms.

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Diran 50mg Tablet

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Reactin 50mg Tablet

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Diclofenac (50mg)

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General Information

Contains

Diclofenac (50mg)

Marketer

Indica Laboratories Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Diran 50mg Tablet should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.

The most common side effects of this medicine include nausea, vomiting, diarrhea, abdominal pain, indigestion, flatulence, decreased appetite, headache, and dizziness. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Diran 50mg Tablet should be used with precaution in patients with asthma and cardiovascular bleeding. This medicine is contraindicated for the treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery. Pregnant and breastfeeding women should consult their doctors before using this medicine as it may cause harmful effects to the developing baby.

Uses of Diran Tablet

Pain relief

Benefits of Diran Tablet

Pain relief
Diran 50mg Tablet belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Diran Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diran

Diarrhea
Flatulence
Vomiting
Headache
Dizziness
Nausea
Constipation
Abdominal pain
Dyspepsia
Decreased appetite
Gastrointestinal bleeding
Vertigo
Gastrointestinal ulcer
Rash
Increased transaminase level in blood
Application site irritation
Injection site pain

How to use Diran Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diran 50mg Tablet is to be taken with food.

How Diran Tablet works

Diran 50mg Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

All substitutes for Diran 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Diran 50mg Tablet to relieve pain and inflammation.
Take it with food or milk to prevent upset stomach.
Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking Diran 50mg Tablet as it can cause excessive drowsiness and increase your risk of stomach problems.
Inform your doctor if you have a history of heart disease or stroke.
Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

UNSAFE

It is unsafe to consume alcohol with Diran 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Diran 50mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Diran 50mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Diran 50mg Tablet may cause side effects which could affect your ability to drive.
Diran 50mg Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.

Kidney

CAUTION

Diran 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Diran 50mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Diran 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Diran 50mg Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Diran with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Fondaparinux (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Severe

Heparin (Injection Route)

Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Is Diran 50mg Tablet a good painkiller?

Diran 50mg Tablet is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Is Diran 50mg Tablet a narcotic?

No, Diran 50mg Tablet is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Diran 50mg Tablet get you high?

No, Diran 50mg Tablet does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Can Diran 50mg Tablet damage your kidneys?

Long-term use and high doses of Diran 50mg Tablet may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Does Diran 50mg Tablet make you drowsy?

Diran 50mg Tablet can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

What is the most important information I need to know about Diran 50mg Tablet?

It is important to know that Diran 50mg Tablet may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Diran 50mg Tablet may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Can Diran 50mg Tablet be taken during pregnancy?

You should not take Diran 50mg Tablet during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Diran 50mg Tablet can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Diran 50mg Tablet during the first 6 months of pregnancy also. In some cases, Diran 50mg Tablet may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Is Diran 50mg Tablet a good painkiller?

Is Diran 50mg Tablet a narcotic?

No, Diran 50mg Tablet is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Diran 50mg Tablet get you high?

Can Diran 50mg Tablet damage your kidneys?

Does Diran 50mg Tablet make you drowsy?

What is the most important information I need to know about Diran 50mg Tablet?

Can Diran 50mg Tablet be taken during pregnancy?

Fact Box

Chemical Class

Phenylacetic acid Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac sodium [Prescribing Information]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2021. [Accessed 06 Apr. 2024] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Indica Laboratories Pvt Ltd
Address: L.B. SHASHTRI ROAD, AHMEDABAD - 3800025

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Diran 50mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Diran Tablet

Benefits of Diran Tablet

Side effects of Diran Tablet

How to use Diran Tablet

How Diran Tablet works

All substitutes for Diran 50mg Tablet

Reactin 50mg Tablet

Inac 50 Tablet

NAC 50 Tablet

Dicloter 50mg Tablet

Delbitol 50mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Fondaparinux (Injection Route)

Heparin (Injection Route)

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

Is Diran 50mg Tablet a good painkiller?

Is Diran 50mg Tablet a narcotic?

Does Diran 50mg Tablet get you high?

Can Diran 50mg Tablet damage your kidneys?

Does Diran 50mg Tablet make you drowsy?

What is the most important information I need to know about Diran 50mg Tablet?

Can Diran 50mg Tablet be taken during pregnancy?

Is Diran 50mg Tablet a good painkiller?

Is Diran 50mg Tablet a narcotic?

Does Diran 50mg Tablet get you high?

Can Diran 50mg Tablet damage your kidneys?

Does Diran 50mg Tablet make you drowsy?

What is the most important information I need to know about Diran 50mg Tablet?

Can Diran 50mg Tablet be taken during pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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