Difen Injection
Prescription Required
Product introduction
Difen Injection is a pain-relieving medicine. It is used to treat pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is given in cases where oral administration is not possible.
Difen Injection is administered as an injection by a healthcare professional. Kindly do not self administer. Inform your doctor if you have any history of heart disease or stroke. Please consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.
The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
Uses of Difen Injection
Benefits of Difen Injection
In Pain relief
Difen Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Difen Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Difen
- Injection site reactions (pain, swelling, redness)
- Vomiting
- Flatulence
- Edema (swelling)
- Nausea
- Headache
- Dizziness
How to use Difen Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Difen Injection works
Difen Injection is a non-steroidal anti-inflammatory drugs (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Difen Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Difen Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Difen Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Difen Injection may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Difen Injection should be used with caution in patients with kidney disease. Dose adjustment of Difen Injection may be needed. Please consult your doctor.
Liver
CAUTION
Difen Injection should be used with caution in patients with liver disease. Dose adjustment of Difen Injection may be needed. Please consult your doctor.
What if you forget to take Difen Injection?
If you miss a dose of Difen Injection, consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- You have been prescribed Difen Injection to relieve pain and inflammation.
- Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Difen Injection as it can cause excessive drowsiness and increase your risk of stomach problems.
- Inform your doctor if you have a history of heart disease or stroke.
- Your doctor may regularly monitor your kidney function, liver function and levels of blood components, if you are taking this medicine for long-term treatment.
Fact Box
Chemical Class
Phenylacetic acid Derivative
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Interaction with drugs
Taking Difen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may increase the risk of serious damage to the kidneys.
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney
Concurrent use may result in fatal Methotrexate poisoning.
Careful consideration is advised when taking Methotrexate with Diclofenac. Your doctor may monitor your treatment and ad
Concurrent use may increase the risk of bleeding.
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Concurrent use may increase the risk of bleeding. Diclofenac may increase the effect of Heparin.
Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor
Concurrent use may result in fatal Methotrexate poisoning.
Careful consideration is advised when taking Methotrexate with Diclofenac. Your doctor may monitor your treatment and ad
Patient concerns
User feedback
What are you using Difen Injection for?
Pain relief
88%
Headache
12%
How much was the improvement?
Excellent
100%
What were the side-effects while using Difen Injection?
No Side Effec*
100%
*No Side Effect
How do you take Difen Injection?
With or witho*
100%
*With or without food
Please rate Difen Injection on price
Not Expensive
100%
FAQs
How should Difen Injection injection be administered?
Difen Injection injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.
What is the most important information I need to know about Difen Injection?
It is important to know that Difen Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Difen Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.
Is Difen Injection a good painkiller?
Difen Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.
Can Difen Injection hurt your kidneys?
Long-term use and high doses of Difen Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.
Does Difen Injection make you drowsy?
Difen Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.
Can Difen Injection be taken during pregnancy?
You should not take Difen Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Difen Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Difen Injection during the first 6 months of pregnancy also. In some cases, Difen Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.
Does Difen Injection get you high?
No, Difen Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
Is Difen Injection a narcotic?
No, Difen Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
- Diclofenac. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2017. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Diclofenac [Prescribing Information]. Lake Forest, IL: Hospira, Inc.; 2014. [Accessed 06 Apr. 2024] (online) Available from:
Marketer details
Name: McW Healthcare
Address: 501, Rafael Tower, Old Palasia, Indore – 452 001 INDIA
Country of origin: India
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