Diclodyne 25 Suppository is a pain-relieving medicine used to treat post-operative pain and inflammation. This route is administered in cases where any other route is not possible, such as unconscious individuals or in children.

Diclodyne 25 Suppository should be taken in the dose and duration as advised by your doctor. It should be taken with food or milk to prevent stomach upset. Inform your doctor if you have any history of heart disease or stroke.
The most common side effects of this medicine include edema, nausea, headache, dizziness, vomiting, constipation, itching, flatulence, pain in extremity, and indigestion. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Diclodyne Suppository

Pain relief

Benefits of Diclodyne Suppository

In Pain relief

Diclodyne 25 Suppository helps relieve pain and inflammation in conditions such as postoperative pain, acute musculoskeletal pain, and arthritis. It may also be used for the management of pain associated with conditions like kidney stones and menstrual cramps.

Side effects of Diclodyne Suppository

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diclodyne

Nausea
Anal irritation
Anal itching
Black colored stool
Headache
Dizziness
Vertigo
Diarrhea
Indigestion
Abdominal pain
Flatulence
Decreased appetite
Increased transaminase level in blood
Rash

How to use Diclodyne Suppository

Remove the wrapper from the suppository before inserting it. Keep lying down for about 15 minutes after insertion so that the suppository does not come out before it melts.

How Diclodyne Suppository works

Diclodyne 25 Suppository is a non-steroidal anti-inflammatory drug (NSAID) that is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

Diclodyne 25 Suppository may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Diclodyne 25 Suppository is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

No interaction found/established

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Diclodyne 25 Suppository in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Diclodyne 25 Suppository should be used with caution in patients with liver disease. Dose adjustment of Diclodyne 25 Suppository may be needed. Please consult your doctor.

What if you forget to take Diclodyne Suppository?

If you miss a dose of Diclodyne 25 Suppository, use it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Diclodyne 25 Suppository

₹8.2/Suppository

Justin 25mg Suppository

Neon Laboratories Ltd

₹14.4/suppository

76% costlier

Diclotaj 25mg Suppository

Taj Pharma India Ltd

₹10.9/suppository

33% costlier

Quick tips

Insert Diclodyne 25 Suppository gently into the rectum, pointed end first, after emptying your bowels for better absorption.
Avoid using more than the prescribed dose, as excessive use can increase the risk of side effects.
Lie down a few minutes after insertion to prevent the suppository from slipping out.
If you experience severe rectal irritation or bleeding, discontinue use and consult your doctor immediately.

Fact Box

Chemical Class

Phenylacetic acid Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

Interaction with drugs

Taking Diclodyne with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Fondaparinux (Injection Route) Severe

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Concurrent use may increase the risk of bleeding.

Heparin (Injection Route) Severe

Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase... More

Tacrolimus (Oral Route) Severe

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations. Co... More

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

Methotrexate (Injection Route) Severe

Please consult with your doctor. Doctor may monitor liver function and blood cell counts. Concurrent use may increase the risk of serious side effects of Methotrexate.

View all drug interactions

Patient concerns

One of my teeth is sensitive. It some times pains

Dr. Abhijit Gambhir

Dental Surgery

sensitivity has many causative factors for relief of pain you can take pain killers it will give temporary relief

fever and 2 months pregnant can take combiflan

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

No take Crocin for pain relief

Is Diclodyne 25 Suppository effective?

Yes, Diclodyne 25 Suppository is effective when used as prescribed by your doctor. They help relieve pain and inflammation, especially in conditions like post-operative pain or arthritis. For the best results, follow the recommended dose and duration. If symptoms persist or worsen, consult your doctor.

In which conditions is the use of Diclodyne 25 Suppository avoided?

The use of Diclodyne 25 Suppository should be avoided by patients who are allergic to Diclodyne 25 Suppository or any of its components. However, if you are not aware of any allergy or if you are using Diclodyne 25 Suppository for the first time, consult your doctor.

Can Diclodyne 25 Suppository be used during pregnancy?

You should not take Diclodyne 25 Suppository during the last 3 months of pregnancy, as it may cause harmful effects on your baby. Use of Diclodyne 25 Suppository can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Diclodyne 25 Suppository after 6 months of pregnancy. In some cases, Diclodyne 25 Suppository may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Is Diclodyne 25 Suppository safe?

Diclodyne 25 Suppository is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any doses. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

Top Rheumatologists

5 ★

4.7 ★

MBBS, DNB, MD, Fellowship, Fellowship

4.7 ★

4.9 ★

4.6 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
Diclofenac [EMC Label]. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 1997 [revised 30 Mar. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac [Product Information Leaflet]. Andheri (East), Mumbai: Bliss GVS Pharma Ltd.; 2022. [Accessed 06 Apr. 2024] (online) Available from:

Marketer details

Name: Bliss Gvs Pharma Limited

Address: Bliss GVS Pharma Ltd., 102,Hyde Park, Saki Vihar Road, Andheri (East),Mumbai – 400072, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.