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Last updated:
03 Jun 2019 | 04:03 PM (IST)
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Diamicron XR Mex 500 Tablet


Overview

Introduction

Diamicron XR Mex 500 Tablet is used in the treatment of type 2 diabetes mellitus.

Diamicron XR Mex 500 Tablet is a combination medicine that can control blood sugar better than a single medication. It should be used along with a proper diet and regular exercise for best results. Hypoglycemia (low blood sugar level) may occur as a side effect and it should be taken with food to avoid stomach upset.

Uses of Diamicron Mex Tablet XR

Side effects of Diamicron Mex Tablet XR

Common
  • Hypoglycemia (low blood sugar level)
  • Taste change
  • Nausea
  • Diarrhea
  • Stomach pain
  • Headache
  • Upper respiratory tract infection

How to use Diamicron Mex Tablet XR

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Diamicron XR Mex 500 Tablet is to be taken with food.

How Diamicron Mex Tablet XR works

Diamicron XR Mex 500 Tablet is a combination of two antidiabetic medicines: Gliclazide and Metformin. Gliclazide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Diamicron XR Mex 500 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Diamicron XR Mex 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Diamicron XR Mex 500 Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Diamicron XR Mex 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Diamicron XR Mex 500 Tablet may be needed. Please consult your doctor.
Use of Diamicron XR Mex 500 Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Diamicron XR Mex 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Diamicron XR Mex 500 Tablet may be needed. Please consult your doctor.
Diamicron XR Mex 500 Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Diamicron XR Mex 500 Tablet
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Quick Tips

  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing or if you have persistent nausea, vomiting, and stomach pain as Diamicron XR Mex 500 Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Patient Concerns

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I am diabetic since 2102 type 2Currentlr taking two medicinesDiamicron xr mex 500
Dr. Sanjay Bhatt
Diabetes Specialist
A person can control his or her sugar levels by regular exercise and walk or regular aerobic exercises at least 30 to 45 minutes per day.MEDICAL NUTRITIONAL THERAPY THAT IS TO MAINTAIN CALORIES INTAKE AS PER BMI .TAKE HELP OF DIABETIC EDUCATOR. VISIT YOU DOCTOR AND FOLLOW ALL WHAT DOCTOR SUGGESTED.IN TIME ALL ROUTINE INVESTIGATIONS SHOULD BE DONE.you should not treat it as disease but start of a healthy life.Uncontrolled sugar levels for long time leads to lower limb weakness which is neuropathy and which is followed by foot ulcers and other complications.online prescription is not allowed without seeing pt.so contact doctor nearby for any change or dose adjustment or visit my clinic at gurgaon sector 52 RdCity snergy multi speciality clinic near SRS MARKETOk continue same treatment
I have type 2 diabetes for last 20 years and consulting Bangkok hospital for my medicines. I am on Insulin 30 HM mixtard 20 and 14 units in morning and evening with 1gm Glycomet SR OD. My doctor recently prescribed Diamicron MR 30mg before breakfast in addition to above medicines. I am visiting India in Feb last week, please suggest and deliver Diamicron 30mg for 6 months doses.
Dr. Sanjay Bhatt
Diabetes Specialist
U can book online on UR adress
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Do you have any questions related to Diamicron XR Mex 500 Tablet ?

User Feedback


FAQs

Q. What is Diamicron Mex?

Diamicron Mex is a combination of two medicines: Gliclazide and Metformin. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves blood glucose levels in adults when taken along with proper diet and regular exercise. Gliclazide lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. This combination is not indicated for the treatment of Type 1 DM.

Q. What are the possible side effects of Diamicron Mex?

The use of Diamicron Mex is associated with common side effects. These side effects may include hypoglycemia (low blood sugar level), altered taste, nausea, stomach pain, diarrhea, headache and upper respiratory tract infection. Its use can also lead to serious but rare side effects like lactic acidosis. On long-term use, it can also lead to vitamin B12 deficiency.

Q. Can the use of Diamicron Mex cause hypoglycemia?

Yes, the use of Diamicron Mex can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

Q. Can the use of Diamicron Mex cause lactic acidosis?

Yes, the use of Diamicron Mex can lead to lactic acidosis. It is a medical emergency which is caused by increased levels of lactic acid in the blood. It is also known as MALA (Metformin associated lactic acidosis). It is a rare side effect associated with the use of metformin. It is avoided in patients with underlying kidney disease, old age patients or who take large amounts of alcohol. Symptoms of lactic acidosis may include muscle pain or weakness, dizziness, tiredness, feeling of cold in arms and legs, difficulty in breathing, nausea, vomiting, stomach pain or slow heart rate. If you have these symptoms, stop taking Diamicron Mex and immediately consult your doctor.

Q. Can the use of Diamicron Mex lead to Vitamin B12 deficiency?

Yes, the use of Diamicron Mex can cause vitamin B12 deficiency on long-term use. The deficiency occurs as the medicine interferes with absorption of vitamin B12 in the stomach. If untreated, it may cause anemia and nerve problems and the patient can have tingling sensation and numbness in hands and feet, weakness, urinary problems, change in mental status and difficulty in maintaining balance (ataxia). To avoid such problems, some researchers suggest an intake of vitamin B12 from outside sources at least once every year.

Q. Are there any specific conditions in which Diamicron Mex should not to be taken?

The use of Diamicron Mex should be avoided in patients with known allergy to any of the component or excipients of this medicine. It is also avoided in patients with moderate to severe kidney disease or with underlying metabolic acidosis including diabetic ketoacidosis.

Q. Is it safe to take alcohol while I am also taking Diamicron Mex?

No, it is not safe to take alcohol along with Diamicron Mex. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Gottwald-Hostalek U, Schlachter J, Geloneze B. Combination Therapy with Metformin plus Gliclazide in Patients with Type 2 Diabetes. J Dia Res Ther. 2016;2(3). [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Gliclazide. Dupnitsa, Bulgaria: Balkanpharma-Dupnitsa AD; 2016. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 13 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Serdia House, Off Dr. S S Rao Road, Behind M G Hospital Parel, Mumbai 400012
A licensed pharmacy from your nearest location will deliver Diamicron XR Mex 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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