Dfn Injection
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Dfn Injection is a pain-relieving medicine. It is used to treat various types of pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is given in cases where oral administration is not possible.
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General Information
The content is shown in English



Product introduction
Dfn Injection is generally administered by a doctor or a nurse. Do not self-administer this medicine at home. Inform your doctor if you have any history of heart disease or stroke. Consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.
The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
Uses of Dfn Injection
Benefits of Dfn Injection
Pain relief
Dfn Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Dfn Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Dfn Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dfn
- Diarrhea
- Flatulence
- Vomiting
- Injection site reactions (pain, swelling, redness)
- Headache
- Dizziness
- Nausea
- Insomnia (difficulty in sleeping)
- Constipation
- Abdominal pain
- Dyspepsia
- Gastrointestinal bleeding
- Gastrointestinal ulcer
- Rash
- Application site irritation
- Injection site pain
How to use Dfn Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Dfn Injection works
Dfn Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
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For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- You have been prescribed Dfn Injection to relieve pain and inflammation.
- Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
- It may cause dizziness, drowsiness, or visual disturbances. Use caution while driving or doing anything that requires concentration.
- Avoid consuming alcohol while taking Dfn Injection as it can cause excessive drowsiness and increase your risk of stomach problems.
- Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Dfn Injection.

Pregnancy
CONSULT YOUR DOCTOR
Dfn Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
CONSULT YOUR DOCTOR
Dfn Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving
UNSAFE
Dfn Injection may cause side effects that could affect your ability to drive.

Kidney
CAUTION
Dfn Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Dfn Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Interaction with drugs
Taking Dfn with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Fondaparinux (Injection Route)
If concurrent use is essential, watch out for bleeding and consult your doctor immediately.
Severe
Heparin (Injection Route)
Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.
Severe
Tacrolimus (Oral Route)
If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe
Methotrexate (Injection Route)
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Frequently asked questions
Dfn Injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in the buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as an infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.
It is important to know that Dfn Injection may increase your chance of having a heart attack or stroke. The risk is higher if you take higher doses and have used the medicine for a long time. Additionally, Dfn Injection may cause ulcers, bleeding, or holes in your stomach and intestine. If you experience any such problems, consult your doctor immediately.
Dfn Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains, and other injuries. It is also helpful in various types of arthritis, gout, pain, and inflammation following surgery.
Long-term use and high doses of Dfn Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include dehydrated people, individuals with heart failure, impaired kidney function, hypertension, and the elderly. Hence, for such patients kidney function monitoring is recommended.
Dfn Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.
No, Dfn Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.
No, Dfn Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.
Long-term use and high doses of Dfn Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.
Dfn Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.
It is important to know that Dfn Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Dfn Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.
You should not take Dfn Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Dfn Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Dfn Injection during the first 6 months of pregnancy also. In some cases, Dfn Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.
Fact Box
Chemical Class
Dichlorobenzenes
Habit Forming
No
Therapeutic Class
PAIN ANALGESICS
Action Class
NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
References
- Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
- Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
- Diclofenac. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2017. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
- Diclofenac [Prescribing Information]. Lake Forest, IL: Hospira, Inc.; 2014. [Accessed 06 Apr. 2024] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Parex Pharmaceuticals Pvt Ltd
Address: D-145, Industrial Area, Phase-VII, MOHALI -160055 India
Address: D-145, Industrial Area, Phase-VII, MOHALI -160055 India
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Dfn Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Dfn Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
Why we need a prescription?
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945














