


Depnon 10mg Tablet
Mianserin (10mg)
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Depnon 10mg Tablet is used in the treatment of depression. This medicine works by increasing the level of chemical messengers (serotonin and noradrenaline) in the brain that help calm the brain and relax the nerves, thus treating your depression.
Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 05 Aug 2026 | 01:01 AM (IST)
Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 05 Aug 2026 | 01:01 AM (IST)
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General Information
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Product introduction
Depnon 10mg Tablet may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly as it may worsen your symptoms.
It even causes dizziness and sleepiness as side effects, so do not drive or do anything that requires mental focus. This medicine may cause weight gain; therefore, you should have a balanced diet and exercise regularly. Moreover, it is important to inform your doctor if you develop a sore throat or fever after taking this medicine.
Uses of Depnon Tablet
Benefits of Depnon Tablet
Depression
Depression is a mental health condition that causes persistent feelings of sadness, loss of interest, and low energy, affecting daily life and overall well-being. Depnon 10mg Tablet helps improve mood, restore emotional balance, and reduce symptoms such as anxiety, sleep disturbances, and lack of motivation. This supports better mental health, improves daily functioning, and enhances overall quality of life.
Depression is a mental health condition that causes persistent feelings of sadness, loss of interest, and low energy, affecting daily life and overall well-being. Depnon 10mg Tablet helps improve mood, restore emotional balance, and reduce symptoms such as anxiety, sleep disturbances, and lack of motivation. This supports better mental health, improves daily functioning, and enhances overall quality of life.
Side effects of Depnon Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Depnon
- Sleepiness
- Increased appetite
- Weight gain
How to use Depnon Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depnon 10mg Tablet may be taken with or without food.
How Depnon Tablet works
Depnon 10mg Tablet is an antidepressant. It works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
Quick tips
- Depnon 10mg Tablet starts to work more quickly than other antidepressants.
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Depnon 10mg Tablet, as it may cause excessive drowsiness and calmness.
- If your doctor asks you to stop Depnon 10mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Notify your doctor immediately if you develop a sore throat or fever or stomatitis during treatment with Depnon 10mg Tablet.
- Depnon 10mg Tablet starts to work more quickly than other antidepressants.
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Depnon 10mg Tablet, as it may cause excessive drowsiness and calmness.
- If your doctor asks you to stop Depnon 10mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Notify your doctor immediately if you develop a sore throat or fever or stomatitis during treatment with Depnon 10mg Tablet.
Safety advice

Alcohol
UNSAFE
Do not drink alcohol while you are taking this medicine. Depnon 10mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Depnon 10mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
CAUTION
Depnon 10mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Depnon 10mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As Depnon 10mg Tablet can make you feel drowsy and can cause blurred vision and this may affect your ability to drive.
As Depnon 10mg Tablet can make you feel drowsy and can cause blurred vision and this may affect your ability to drive.

Kidney
CAUTION
Depnon 10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Depnon 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs
Taking Depnon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening
Moclobemide (Oral Route)
Do not consume Moclobemide with Mianserin. If Moclobemide is essential, ensure a gap of at least 1 week after discontinuing Mianserin. Please consult your doctor.
Life-threatening
Tranylcypromine (Oral Route)
Do not consume Tranylcypromine with Mianserin. If Tranylcypromine is essential, ensure a gap of At least 2 weeks after discontinuing Mianserin. Please consult your doctor.
Moderate
Clozapine (Oral Route)
Your doctor may monitor your blood cell count and adjust the doses as per the observations.
Moderate
Linezolid (Oral Route)
Do not consume Linezolid with Mianserin. If concurrent use is essential, watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor your blood pressure frequently.
Moderate
Linezolid (Injection Route)
Do not consume Linezolid with Mianserin. If concurrent use is essential, watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Your doctor may monitor your blood pressure frequently.
Fact Box
Chemical Class
Dibenzazepines
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Noradrenergic and Specific Serotonergic Antidepressants (NaSSAs)
References
- Stahl SM, editor. Mianserin. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 425-29.
- Mianserin hydrochloride. Hatfield, Hertfordshire: Generics UK T/A Mylan; 2003 [revised Jan. 2014]. [Accessed 25 Mar 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Infar India Ltd
Address: Apejay Chamber, Wallace St, Fort, Mumbai - 400001
Address: Apejay Chamber, Wallace St, Fort, Mumbai - 400001
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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