DEPAKENE SYRUP

Prescription Required
Manufacturer
Storage
Store at room temperature (10-30°C)

Introduction

DEPAKENE SYRUP is a prescription medicine used to treat epilepsy (seizures) and bipolar disorder. It is also used in the prevention of migraine. It has a calming effect on the brain by relaxing the nerves.

DEPAKENE SYRUP may be taken with or without food, preferably at the same time, each day. Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. Never skip any doses and finish the full course of treatment even if you feel better. Do not stop taking it abruptly without discussing it with your doctor, as it may increase seizure frequency.

Some of the common side effects of this medicine include headache, blurred vision, loss of appetite, nausea, vomiting, hair loss and diarrhea. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain, and to control it, you should have a balanced diet and exercise regularly. Please consult your doctor if these side effects bother you or do not go away.

Uses of Depakene Syrup

Benefits of Depakene Syrup

In Epilepsy/Seizures

DEPAKENE SYRUP is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

In Prevention of Migraine

It is not fully established how DEPAKENE SYRUP helps prevent migraines. It may change the abnormal and excessive activity of the nerve cells in the brain or increase the activity in a region of the brain associated with migraines. By preventing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

In Bipolar disorder

DEPAKENE SYRUP works to restore the normal balance of nerve activity in your brain. It can help prevent extreme changes in mood and help you feel less agitated. You may experience fewer episodes of low mood. It can take several weeks for this medicine to work and you may still feel low during this time. It is likely that you will take this medicine for at least six months but possibly much longer. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Depakene Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Depakene

  • Headache
  • Dizziness
  • Blurred vision
  • Loss of appetite
  • Nausea
  • Vomiting
  • Sleepiness
  • Hair loss
  • Weight gain
  • Tremor
  • Double vision
  • Diarrhea
  • Impaired coordination
  • Increased appetite
  • Weakness
  • Stomach pain

How to use Depakene Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. DEPAKENE SYRUP is to be taken with food.

How Depakene Syrup works

DEPAKENE SYRUP is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with DEPAKENE SYRUP.
Pregnancy
CONSULT YOUR DOCTOR
DEPAKENE SYRUP is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
DEPAKENE SYRUP is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
DEPAKENE SYRUP may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
DEPAKENE SYRUP should be used with caution in patients with kidney disease. Dose adjustment of DEPAKENE SYRUP may be needed. Please consult your doctor.
However, talk to your doctor if you have any underlying kidney disease.
Liver
UNSAFE
DEPAKENE SYRUP is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
Use of DEPAKENE SYRUP is not recommended in patients with severe liver disease and active liver disease.

What if you forget to take Depakene Syrup?

If you miss a dose of DEPAKENE SYRUP, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • It may cause cosmetic side effects such as increased hair growth on the face, acne and thinning of hair. Talk to your doctor if this bothers you.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Valproic Acid Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS

Interaction with Drugs

Taking Depakene with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam, Tenzo, Indolam
SERIOUS
Brand(s): Bupro, Bupep, Bunocare
SERIOUS
Brand(s): Carz, Antep, C Lep
SERIOUS
Brand(s): Equblam
SERIOUS

Patient Concerns

arrow
Treatment about bipolar disorder
Dr. Ravi Shankar M.
Ayurveda
Tab. Manasa Mitra Vataki 1-0-1 and Kalyanaka Ghritam 10 gram twice a day with luke warm wtar after food and Sarswatharishta 15 ml twice a day with equal quantity of water for 2 months
Suffering from bipolar disorder
Dr. Jyoti Kapoor Madan
Psychiatry
Bipolar Affective Disorder is a chronic problem caused by Neuro chemical disturbance in brain. It is characterised by excessive mood swings leading to disruption in routine life. Treatment is with mood stabilizer medicines and antipsychotic medicines which may need to continue throughout life. Please see a psychiatrist for further guidance.
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FAQs

Q. I have been taking DEPAKENE SYRUP for a year, and I did not have any episode of seizure during this time. For how long should I take it to cure my epilepsy completely?

DEPAKENE SYRUP does not cure your condition, it only prevents the seizures from occurring. Therefore, you will have to keep on taking it, maybe for years. Consult your doctor if face any problems while taking this medicine.

Q. What happens if I stop taking DEPAKENE SYRUP?

You should not stop taking DEPAKENE SYRUP suddenly. It should be discontinued gradually. Stopping it suddenly may increase the chances of recurrence of seizures. Always consult your doctor if you feel the need to stop taking this medicine.

Q. I have gained weight after I started using DEPAKENE SYRUP. Is it because of this medicine? What should I do?

Yes, weight gain can occur with the use of DEPAKENE SYRUP. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.

Q. Can I take birth control pills while taking DEPAKENE SYRUP?

Yes, DEPAKENE SYRUP does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of DEPAKENE SYRUP and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the DEPAKENE SYRUP levels in your blood levels.

Q. Is it safe to take DEPAKENE SYRUP for long term?

Many patients can safely take DEPAKENE SYRUP for a long time. Rarely, long-term use of DEPAKENE SYRUP may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking DEPAKENE SYRUP for a long time, get regular check ups done for bone health.

Q. I am concerned because I have heard that DEPAKENE SYRUP causes hair loss. Is it true?

DEPAKENE SYRUP may cause thinning of hair, change of hair colour and even hair loss. If you are concerned talk to your doctor if it is possible to reduce the dose of DEPAKENE SYRUP. Your hair may regrow after either reducing your dose or switching to a different medicine.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. McNamara JO. Pharmacotherapy of the Epilepsies. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 596-98.
  2. Porters RJ, Meldrum BS. Antiseizure Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 413-15.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1449-54.
  4. Valporic acid. Barceloneta, PR :AbbVie LTD; 1978 [revised Feb 2016]. [Accessed 19 Mar 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
DISCONTINUED
We do not facilitate sale of this product at present

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