


Defpea 6mg Syrup
Product Summary :
Defpea 6mg Syrup contains deflazacort, a medicine used to treat Duchenne muscular dystrophy. It helps maintain muscle strength and slow the progression of muscle weakness. It is usually taken once daily, with or without food. Common side effects include weight gain, increased appetite, facial rounding, and cough. Regular monitoring of growth, bone health, blood pressure, and blood sugar is important during treatment.Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Oct 2026 | 02:56 PM (IST)
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General Information



Your child’s medicine at a glance
Give Defpea 6mg Syrup to your child orally, either before or after food. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself, as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.
It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Defpea 6mg Syrup can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Defpea 6mg Syrup can impact both of these.
This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, and fluid and electrolyte disturbance. Reach out to your child’s doctor if these side effects appear.
Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.
Uses of Defpea 6mg Syrup in children
- Treatment of Duchenne muscular dystrophy(DMD)
Benefits of Defpea 6mg Syrup for your child
Duchenne muscular dystrophy is a genetic condition that causes gradual muscle weakness, making everyday movements like walking, climbing stairs, and lifting objects increasingly difficult over time. Defpea 6mg Syrup helps reduce muscle inflammation and damage associated with this condition, which supports better preservation of muscle strength and function. With continued use, it can help slow disease progression, maintain mobility for a longer period, and support overall physical functioning and quality of life.
Side effects of Defpea 6mg Syrup in children
- Weight gain
- Increased appetite
- Cough
- Pollakiuria
- Excessive hair growth on face
- Central obesity
- Nasopharyngitis (inflammation of the throat and nasal passages)
- Cushing syndrome
- Upper respiratory tract infection
How can I give Defpea 6mg Syrup to my child?
Avoid Defpea 6mg Syrup with grapefruit juice.
How Defpea Syrup works
Dosage
Defpea 6mg Syrup is usually taken once daily, with or without food, as prescribed by your child’s doctor. The dose is determined according to body weight, age, response to treatment, and other medicines being taken. Do not take Defpea 6mg Syrup with grapefruit juice. Do not stop giving it suddenly, as the dose may need to be reduced gradually.
All substitutes for Defpea 6mg Syrup
Defahit 6mg Syrup
Vexicort 6mg Syrup
Defton 6mg Syrup
Defrich Syrup
Docoflam 6mg Syrup
Quick tips
- Prefer giving Defpea 6mg Syrup with food as an empty stomach can trigger acidity and gastric reflux.
- Avoid giving antacids along with Defpea 6mg Syrup. If both need to be given, leave a gap of at least 2 hours between administration of Defpea 6mg Syrup and antacids.
- Do not give it more often or for longer than advised by your doctor.
- Defpea 6mg Syrup can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
- Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.
Safety advice

Kidney
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Defpea 6mg Syrup to your child.

Liver
Interaction with drugs
Gliclazide (Oral Route)
Glibenclamide (Oral Route)
Frequently asked questions
Fact Box
Chemical Class
Habit Forming
Therapeutic Class
Action Class
References
- University of Michigan: C.S. Mott Children’s Hospital. Deflazacort. [Updated 19 Ju. 2019]. [Accessed 18 Feb. 2021] (online) Available from:
- Memorial Sloan Kettering Cancer Center. Deflazacort. [Accessed 18 Feb. 2021] (online) Available from:
- Emflaza (deflazacort). Frequently asked questions. [Accessed 18 Feb. 2021] (online) Available from:
- Deflazacort [Prescribing Information]. Northbrook, IL: Marathon Pharmaceuticals, LLC; 2017. [Accessed 20 Feb. 2024] (online) Available from:
- Deflazacort [Prescribing Information]. Hyderabad, India: Aurobindo Pharma Limited; 2024.[Accessed 11 Mar. 2026] (online) Available from:
- Deflazacort. Hyderabad, Telangana: Aurobindo Pharma Limited; 2026. [Accessed 05 Jan. 2026] (online). Available from:




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Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)



