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Deflatrix Syrup 1
Deflatrix Syrup 2
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Deflatrix Syrup

Deflazacort (6mg/5ml)
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Product Summary :

Deflatrix Syrup contains deflazacort, a medicine used to treat Duchenne muscular dystrophy. It helps maintain muscle strength and slow the progression of muscle weakness. It is usually taken once daily, with or without food. Common side effects include weight gain, increased appetite, facial rounding, and cough. Regular monitoring of growth, bone health, blood pressure, and blood sugar is important during treatment.


Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Oct 2026 | 02:56 PM (IST)
₹54.9 MRP ₹59.067% off 
(Inclusive of applicable taxes)
 
 
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General Information

The content is shown in English
Deflatrix Syrup 1
Deflatrix Syrup 2

Product introduction

Deflatrix Syrup is a corticosteroid medicine used in Duchenne muscular dystrophy. It helps reduce muscle inflammation and damage, supporting muscle strength and slowing the progression of muscle weakness over time.

Give Deflatrix Syrup to your child orally, either before or after food. Always give the dose as prescribed by the doctor since that depends on the severity and type of infection, body weight, and age of your child. If your child gains or loses weight during treatment, make sure to let the doctor know. Never alter the dose by yourself, as that may increase the risk of serious implications in your child. If your child vomits within 30 minutes of taking this medicine, help the child calm down and repeat the same dose, but skip it if it is already time for the next dose.


It is important to complete the full course of this medicine as stopping it abruptly may cause serious side effects. To stop this medicine, the doctor will gradually taper down the dose of this medicine to avoid withdrawal symptoms. Deflatrix Syrup can suppress your child’s immune system, making your child more prone to infections. Your child may need frequent medical checkups and tests. Therefore, it is important to follow up with your child’s doctor frequently during the treatment. The doctor may also advise vision and bone mineral density check for your child as Deflatrix Syrup can impact both of these.


This medicine may cause side effects like weight gain, increased appetite, upper respiratory tract infection, cough, abnormal hair growth, central obesity, and fluid and electrolyte disturbance. Reach out to your child’s doctor if these side effects appear.


Let your child’s doctor know if your child is already taking medicines for any type of infection. Also, narrate your child’s complete medical history, including heart, blood, skin, bone, and hormonal disorders or any prior episodes of allergy, eye disease, birth defects, lung anomaly, liver impairment, and kidney malfunction. This information is critical for dose alterations and in planning your child’s overall treatment.

Uses of Deflatrix Syrup

  • Treatment of Duchenne muscular dystrophy(DMD)

Benefits of Deflatrix Syrup

Treatment of Duchenne muscular dystrophy(DMD)
Duchenne muscular dystrophy is a genetic condition that causes gradual muscle weakness, making everyday movements like walking, climbing stairs, and lifting objects increasingly difficult over time. Deflatrix Syrup helps reduce muscle inflammation and damage associated with this condition, which supports better preservation of muscle strength and function. With continued use, it can help slow disease progression, maintain mobility for a longer period, and support overall physical functioning and quality of life.

Side effects of Deflatrix Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Deflatrix
  • Weight gain
  • Increased appetite
  • Cough
  • Pollakiuria
  • Excessive hair growth on face
  • Central obesity
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Cushing syndrome
  • Upper respiratory tract infection

How to use Deflatrix Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Deflatrix Syrup may be taken with or without food.
Avoid Deflatrix Syrup with grapefruit juice.

How Deflatrix Syrup works

Deflatrix Syrup is a corticosteroid medicine. It acts like the body’s natural anti-inflammatory hormones called glucocorticoids. Deflatrix Syrup decreases the formation of chemical substances like prostaglandins, leukotrienes, and interleukins that are involved in inflammation, allergy, and cell multiplication. It also suppresses the immune system and stops the immune mechanisms from causing any self-damage to the body.

Dosage

Deflatrix Syrup is usually taken once daily, with or without food, as prescribed by your child’s doctor. The dose is determined according to body weight, age, response to treatment, and other medicines being taken. Do not take Deflatrix Syrup with grapefruit juice. Do not stop giving it suddenly, as the dose may need to be reduced gradually.

Quick tips

  • Prefer giving Deflatrix Syrup with food as an empty stomach can trigger acidity and gastric reflux.
  • Avoid giving antacids along with Deflatrix Syrup. If both need to be given, leave a gap of at least 2 hours between administration of Deflatrix Syrup and antacids.
  • Do not give it more often or for longer than advised by your doctor.
  • Deflatrix Syrup can make it harder for your child to fight off infections. Notify your doctor if you notice any signs of infection such as a fever or sore throat.
  • Do not stop the medicine abruptly. Seek the doctor’s guidance to taper the dose gradually as sudden withdrawal may result in a steroid withdrawal syndrome.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Deflatrix Syrup
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Deflatrix Syrup during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Deflatrix Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Deflatrix Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Deflatrix Syrup is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Dose alterations may be required in severe kidney disease. Discuss with your child’s doctor thoroughly before giving Deflatrix Syrup to your child.
Liver

Liver

CAUTION
Deflatrix Syrup should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Deflatrix with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Chloroquine (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Loperamide (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Gliclazide (Oral Route)

Your doctor may monitor your blood glucose levels along with your overall treatment closely and adjust the doses as per the observations. Deflazacort may reduce the efficacy of Gliclazide.
Moderate

Azithromycin (Oral Route)

Your doctor may monitor your potassium levels closely.
Moderate

Glibenclamide (Oral Route)

Your doctor may monitor your blood glucose levels along with your overall treatment closely and adjust the doses as per the observations. Deflazacort may reduce the efficacy of Glibenclamide.

Frequently asked questions

Yes, Deflatrix Syrup is a steroid medicine also known as glucocorticoids which occur naturally in the body. These glucocorticoids help to maintain health and wellbeing. Deflatrix Syrup increases the corticosteroids levels in the body which helps in treating various illnesses involving inflammation (redness, tenderness, heat and swelling).
Avoid giving Deflatrix Syrup to your child if they have conditions like cardiac disease or congestive heart failure (except in the presence of active rheumatic carditis), hypertension, thromboembolic disorders, or diabetes mellitus. Deflatrix Syrup should also be avoided if your child has a family history of active TB, active herpes infection, osteoporosis, myasthenia gravis, or renal insufficiency.
For certain vaccines (live or live-attenuated vaccines), your child will need to wait 4 to 6 weeks before starting Deflatrix Syrup. Hence, your child needs to receive all immunizations according to immunization guidelines before they start taking Deflatrix Syrup.
Ans: Prolonged intake of Deflatrix Syrup can lead to mental illness as well as a seizure disorder. Therefore, any child who is already suffering from seizure disorder should not take Deflatrix Syrup.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Glucocorticoids
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Matrix Pharma Chem
Address: 90/1 & 91/1, g.i.d.c., opp. ambicanagar, near labela hotel, odhav, ahmedabad - 382 415, gujarat, india.

Vendor Details

Country of origin: India
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