Dapsone 50mg Tablet

Dapsone (50mg)

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Dapsone 50mg Tablet belongs to a class of drugs known as anti-leprotic medicines. It is used to treat leprosy and dermatitis herpetiformis. It works by stopping the growth of disease-causing organisms in the body. It also helps to reduce redness and swelling associated with acne (commonly known as pimples).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Apr 2026 | 12:59 PM (IST)

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General Information

Contains

Dapsone (50mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dapsone 50mg Tablet should be used in the dose and duration as advised by your doctor. It should be taken with or without food, preferably at a fixed time. Avoid skipping any doses and finish the full course of treatment even if you feel better. Do not take a double dose to make up for a missed dose. Simply take the next dose as planned.

Some people may develop a skin rash and fever as side effects of this medicine. It may also cause nausea and vomiting. Consult your doctor if these side effects bother you or persist for a longer duration.

Dapsone 50mg Tablet should be used with caution in individuals with glucose-6-phosphate dehydrogenase (G6PD) deficiency, as it may increase the risk of hemolysis. Careful monitoring is also required in patients with anemia, liver impairment, or pre-existing blood disorders. It is contraindicated in patients with known hypersensitivity to sulfone drugs. Regular blood counts and liver function tests may be advised during treatment. If symptoms such as fatigue, pale skin, dark urine, or skin rash occur, seek medical attention promptly.

Uses of Dapsone Tablet

Leprosy
Dermatitis Herpetiformis

Benefits of Dapsone Tablet

Leprosy
Leprosy is a long-term infection that affects the skin and nerves, leading to skin lesions and nerve damage if untreated. Dapsone 50mg Tablet helps control the infection by stopping the growth of the bacteria, which reduces the spread of the disease and supports gradual healing when used as part of combination therapy.

Dermatitis Herpetiformis
Dermatitis herpetiformis is a condition that causes intense itching, burning, and blistering of the skin. Dapsone 50mg Tablet helps reduce these symptoms by controlling the underlying inflammatory response, providing relief from itching, and improving skin appearance.

Side effects of Dapsone Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dapsone

Rash
Fever
Nausea
Vomiting

How to use Dapsone Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dapsone 50mg Tablet may be taken with or without food.

How Dapsone Tablet works

Dapsone 50mg Tablet helps stop the growth and multiplication of the bacteria causing the infection. It interferes with the production of essential components (folic acid / dihydrofolic acid) needed by the bacteria to survive and multiply. This reduces the spread of infection, helps control symptoms, and supports gradual recovery when used as part of combination therapy.

Quick tips

Inform your doctor if your condition does not improve or if you get eye or nerve problems, and inform your doctor if you have G6PD deficiency, anemia, or any blood-related disorder.
Regular blood tests may be required to monitor safety during treatment.
Watch for symptoms such as fatigue, breathlessness, dark urine, or skin rash and report them promptly.
Maintain proper hygiene and follow medical advice to support recovery and prevent complications.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dapsone 50mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Dapsone 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Dapsone 50mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

SAFE

Dapsone 50mg Tablet does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Dapsone 50mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Dapsone 50mg Tablet in patients with liver disease.

Interaction with drugs

Taking Dapsone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Saquinavir (Oral Route)

Do not consume Dapsone with Saquinavir. If concurrent use is essential, watch out for symptoms of Saquinavir side effects such as nausea, headache, numbness, fever, dizziness, stomach pain or blurred vision and consult your doctor if you experience them. They may adjust the doses as per the observations. Saquinavir may raise blood levels of Dapsone.

Moderate

Clozapine (Oral Route)

Your doctor may monitor your blood cell count and adjust the doses as per the observations.

Moderate

Valganciclovir (Oral Route)

Do not consume Valganciclovir with Dapsone. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Dapsone may raise blood levels of Valganciclovir.

Moderate

Ganciclovir (Injection Route)

Do not consume Ganciclovir with Dapsone. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Dapsone may raise blood levels of Ganciclovir.

Moderate

Ganciclovir (Oral Route)

Frequently asked questions

Who should not use Dapsone 50mg Tablet?

Use of Dapsone 50mg Tablet should be avoided in patients who are allergic to Dapsone 50mg Tablet or any of its components. However, if you are not aware of any allergy or if you are using Dapsone 50mg Tablet for the first time, consult your doctor.

Is Dapsone 50mg Tablet safe?

Dapsone 50mg Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What if I forget to take a dose of Dapsone 50mg Tablet?

If you forget a dose of Dapsone 50mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Can I stop taking Dapsone 50mg Tablet when I feel better?

No, do not stop taking Dapsone 50mg Tablet without consulting the doctor even if you feel better. Your symptoms may improve before the infection is completely cured. Therefore, for better and complete treatment, it is advised to continue your treatment for the prescribed duration. Stopping Dapsone 50mg Tablet too early may cause symptoms to reoccur or worsen. Continue taking Dapsone 50mg Tablet in the dose and duration advised by the doctor.

Can I take a higher than the recommended dose of this medicine?

No, Dapsone 50mg Tablet should be taken in the recommended dose only. Overdose of Dapsone 50mg Tablet can increase the risks of side effects. If you experience an increase in the severity of your symptoms while being on the prescribed dose, please consult your doctor for re-evaluation.

What if I don't get better after using Dapsone 50mg Tablet?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, let your doctor know if your symptoms are getting worse while using this medicine. The doctor may modify the dose or suggest an alternative medicine.

Fact Box

Chemical Class

Benzenesulfonyl compounds

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Antileprotic Agents

References

Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1563-64.
Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 831.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 354-56.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
Dapsone [Prescribing Information]. East Windsor, New Jersey: Novitium Pharma LLC; 2019. [Accessed 06 Apr. 2024] (online) Available from:
Dapsone. Brunswick, NJ: Rising Pharma Holdings, Inc.; 2026.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

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Why we need a prescription?

Dapsone 50mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dapsone Tablet

Benefits of Dapsone Tablet

Side effects of Dapsone Tablet

How to use Dapsone Tablet

How Dapsone Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Saquinavir (Oral Route)

Clozapine (Oral Route)

Valganciclovir (Oral Route)

Ganciclovir (Injection Route)

Ganciclovir (Oral Route)

Frequently asked questions

Who should not use Dapsone 50mg Tablet?

Is Dapsone 50mg Tablet safe?

What if I forget to take a dose of Dapsone 50mg Tablet?

Can I stop taking Dapsone 50mg Tablet when I feel better?

Can I take a higher than the recommended dose of this medicine?

What if I don't get better after using Dapsone 50mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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