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Composition for DAORYL

Glimepiride(1 mg)

food interaction for DAORYL

alcohol interaction for DAORYL

pregnancy interaction for DAORYL

lactation interaction for DAORYL

It is better to take Daoryl 1mg capsule with food.
Taking glimepiride with alcohol may affect blood glucose levels in patients with diabetes.
Daoryl 1mg capsule may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Glimepiride(1 mg)


Daoryl 1mg capsule is used to lower the blood sugar levels in type 2 diabetes mellitus when diet, physical exercise and weight reduction alone are not adequate.

How it works

Daoryl 1mg capsule belongs to a blood sugar lowering group of medicines called sulfonylurea. Daoryl 1mg capsule increases the amount of insulin released by the pancreas, and thereby decreases the blood sugar level.

Common side effects

Nausea, Diarrhoea, Bruise, Bleeding, Blood in stool, Dark colored urine, Dizziness, Sore throat, Stomach pain / epigastric pain, Yellow discoloration of skin, Yellow discoloration of eye, Weakness, Fever


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Expert advice for DAORYL

  • Take glimepiride just before or with the first main meal of the day.
  • Do not skip any meal while taking glimepiride.
  • Swallow the glimepiride tablet without crushing or chewing with at least half a glass of water.
  • Do not take glimepiride if you are allergic to  glimepiride, other sulfonylureas, sulfonamides
  • Glimepiride tablets should not be given to children and adolescents under 18 years of age.

Frequently asked questions for DAORYL


 Q. Is glimepiride a generic drug?
Yes, glimepiride is a generic drug sold under several pharmaceutical brand names (Amaryl, Zoryl, etc.).
Q. Can I take glimepiride with metformin or insulin?
Glimepiride may be given in combination with metformin and/or insulin depending on your medical condition and as prescribed by the doctor.
Q. Does glimepiride cause fluctuations in weight,diarrhea, hair loss, erectile dysfunction, swelling, constipation?
Glimepiride is reported to cause low blood sugar level,weight gain, and swelling, but is not reported to cause diarrhea, constipation, hair loss, or erectile dysfunction.
Q. Is glimepiride a fast acting sulfa drug?
Glimepiride is a medium- to long-acting sulfonylurea drug against type 2 diabetes mellitus (action lasts for 24 hours). Its maximum effect is seen after 2-3 hours of drug intake.
Q. Is glimepiride same as glipizide, glyburide, metformin, or insulin?
They are not same. Glimepiride, glipizide and glyburide belong to the same class of drugs called sulfonylureas. Metformin belong to class called biguanides.Glimepiride causes release of insulin but it is not insulin.It should only be used if no other alternative drug is available. Please follow your doctor's advice regarding its use.


Content on this page was last updated on 11 July, 2015, by Dr. Varun Gupta (MD Pharmacology)