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Cordarone Injection 3ml

Amiodarone (150mg)
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Cordarone Injection 3ml is used to treat various types of serious irregular heartbeat (arrhythmia) such as fibrillation and tachycardia (increased heart rate). It is an anti-arrhythmic type of medicine which rapidly restores your heart to a steady and regular rhythm.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 05 May 2026 | 05:29 PM (IST)
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3 ml Injection
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General Information

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Cordarone Injection 3ml image
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Cordarone Injection 3ml image

Product introduction

Cordarone Injection 3ml is given by a slow drip (infusion) into a vein under the supervision of a doctor. Continuous monitoring of blood pressure and heart rate may be needed while this medicine is administered. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injection. If you stop taking this medicine, you may get dangerous uneven heartbeats, which can be life-threatening.

The most common side effects of this medicine include decreased blood pressure (hypotension), decreased heart rate (bradycardia), blurred vision, and application site reaction(pain, itching, and skin redness). This medicine can also cause problems with your liver, lungs, nerves, and thyroid gland. Ask your doctor what signs to look out for and report any symptoms you have. This medicine takes a long time to get cleared from the body. You may continue to have side effects after you stop using it. Ask your doctor about ways to prevent or reduce them.

Uses of Cordarone Injection

Benefits of Cordarone Injection

Treatment of Arrhythmia
Arrhythmia is a condition in which the heart beats irregularly, either too fast or too slow, which can affect blood circulation and increase the risk of complications. Cordarone Injection 3ml helps restore a regular heart rhythm and maintains steady heartbeats. This improves heart function and lowers the risk of serious outcomes related to abnormal heart rhythms.

Side effects of Cordarone Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cordarone
  • Decreased blood pressure
  • Blurred vision
  • Slow heart rate
  • Application site reactions (burning, irritation, itching and redness)

How to use Cordarone Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cordarone Injection works

Cordarone Injection 3ml is an anti-arrhythmic medication. It regulates heart beat by blocking abnormal electrical signals in the heart.

Quick tips

  • Cordarone Injection 3ml may cause blurring of vision. Avoid driving or any activity requiring focus until you know how it affects you.
  • It makes your skin sensitive towards sunlight. Use a sunscreen and wear protective clothing while going out.
  • Your doctor may do regular blood tests, chest X-rays, ECG, eye test, thyroid, liver and lung function tests while you are taking this medicine.
  • Notify your doctor if you develop breathlessness, persistent cough, jaundice, restlessness, weight loss/gain or eye problems.
  • Notify your doctor about all other medicines that you are taking as Cordarone Injection 3ml can interact with many medicines.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cordarone Injection 3ml. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Cordarone Injection 3ml is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Cordarone Injection 3ml is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

UNSAFE
Cordarone Injection 3ml may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Cordarone Injection 3ml should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, inform your doctor if you have an underlying kidney disease.
Liver

Liver

CAUTION
Cordarone Injection 3ml should be used with caution in patients with liver disease. Dose adjustment may be needed.
Cordarone Injection 3ml may cause hepatic injury. Dose adjustment may be required.

Interaction with drugs

Taking Cordarone with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Amiodarone.
Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Amiodarone.
Life-threatening

Voriconazole (Oral Route)

Do not consume Voriconazole with Amiodarone.
Life-threatening

Fluconazole (Oral Route)

Do not consume Fluconazole with Amiodarone.
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Amiodarone.

Frequently asked questions

Generally, an oral tablet of Cordarone Injection 3ml does not affect blood pressure. But, when given through an injection intravenously (in the vein) then it may decrease in the blood pressure. To prevent this your doctor or nurse may give Cordarone Injection 3ml slowly. Along with that, you may also be prescribed medicines which increase blood pressure (vasopressor agents) to the infusion.
The warning signals of liver toxicity include yellowing of the skin or eyes (jaundice), tiredness, nausea, vomiting, dark-colored urine, pale-colored stools, loss of appetite, stomach pain or high temperature. Contact your doctor immediately if you experience these symptoms.
You may experience blurred vision or see a circle around dazzling light (halos). It may also make your eyes dry or sensitive to light. It can even cause permanent blindness. Therefore, consult your doctor in case you experience any such problems while on Cordarone Injection 3ml.
Cordarone Injection 3ml blocks certain electrical signals in the heart that can cause an irregular heartbeat (arrhythmia). This way, it helps to restore normal heart rhythm and maintains a regular, steady heartbeat.

Fact Box

Chemical Class

Aryl- phenyl ketones

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Class III Antiarrhythmics

References

  1. Sampson KJ, Kass RS. Anti-Arrhythmic Drugs. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 834-37.
  2. Hume JR, Grant AO. Agents Used in Cardiac Arrhythmias. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 240-41.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 54-57.
  4. Nattel S, Gersh BJ, Opie LH. Antiarrhythmic Drugs and Strategies. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 288-95.
  5. Amiodarone Hydrochloride [Prescribing Information]. Schaumburg, IL: Sagent Pharmaceuticals, Inc.; 2021. [Accessed 09 Jun, 2023] (online) Available from:
  6. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 14 Mar. 2019] (online) Available from:
  7. Central Drugs Standard Control Organisation (CDSCO). Amiodarone. [Accessed 14 Mar. 2019] (online) Available from:
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User feedback

Once A Month
33%
Once A Day
33%
Once A Week
25%
Twice A Week
8%
Arrhythmia
100%
Average
42%
Excellent
42%
Poor
17%
Nausea
33%
Slow heart rate
33%
Constipation
17%
Increased liver enzymes
17%
With or without food
67%
With food
33%
Average
78%
Expensive
22%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sanofi India Ltd
Address: Sanofi House, CTS No.117-B, L&T Business Park, Saki Vihar Road, Powai, Mumbai 400072

Vendor Details

Country of origin: France
A licensed vendor partner from your nearest location will deliver Cordarone Injection 3ml. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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