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Advanced International Certification Course in Diabetes, Cardio-diabetes, Thyroid and Endocrine Disorders, BDS
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Writing in Medical Sciences, Medical Writing, Advanced PG Diploma in Clinical Research
Last updated on:
05 Dec 2018 | 05:29 PM (IST)
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Clonotril 1 Tablet


Overview

Uses of Clonotril Tablet

Clonotril 1 Tablet is used in the treatment of epilepsy and anxiety disorder.

Clonotril Tablet side effects

Common
  • Memory impairment
  • Dizziness
  • Tiredness
  • Sleepiness
  • Depression
  • Confusion
  • Uncoordinated body movements

How to use Clonotril Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonotril 1 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Clonotril Tablet works

Clonotril 1 Tablet is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Clonotril Tablet related warnings

Alcohol
CAUTION
Clonotril 1 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
WEIGH RISKS VS BENEFITS
Clonotril 1 Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Lactation
Clonotril 1 Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Clonotril 1 Tablet may cause side effects which could affect your ability to drive.
Kidney
Clonotril 1 Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Clonotril 1 Tablet may not be needed in these patients. Please consult your doctor.
Use of Clonotril 1 Tablet can cause excessive sleepiness in patients with end stage kidney disease.
Liver
Clonotril 1 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Clonotril 1 Tablet may be needed. Please consult your doctor.

What if you miss a dose of Clonotril Tablet?

If you miss a dose of Clonotril 1 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Clonotril 1 Tablet
₹4.28/Tablet
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Zapiz 1mg Tablet
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Petril 1 Tablet
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Clozepam 1mg Tablet
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Expert Advice

  • If you are taking Clonotril 1 Tablet for the treatment of insomnia and anxiety, it should not be used more than 4 weeks.
  • It may become less effective over the time.
  • It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
  • Avoid consuming alcohol when taking the Clonotril 1 Tablet, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • The addiction / habit-forming potential of Clonotril 1 Tablet is very high.

Interaction with Drugs

Taking Clonotril with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Altole, Pandosun
SERIOUS
Brand(s): Indizole, Itracip, Itraspan
SERIOUS
Brand(s): Norma
SERIOUS
Brand(s): Oxzey
SERIOUS
Brand(s): Valkid
SERIOUS
Brand(s): Stoin
SERIOUS
Brand(s): R Zep
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Imirise
SERIOUS
Brand(s): Ulcevin, Altirab, Rabsure
SERIOUS

Patient Concerns

Questions Related to Clonotril

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Sir, my doctor had prescribed me pexti cr 12 .5 for my anxiety disorder. I had taken this medicine for 4 months and now my stopped this medication. After stopping it i feel moderately nauseated. My question is how long it will take to feel normal again?
Dr. Pushkar Mani
Diabetes Specialist
another month, take Ondem 4mg once daily in mornig
I m suffering from anxiety ,, prescribed me setarline 100 mg ( daxid) how long I can take this medicine ,, can I use it's low cost substitute ,, plz suggest
Dr. Jyoti Kapoor Madan
Psychiatrist
Maintenance phase after first episode of anxiety disorder lasts for 6 months,medicines are then gradually tapered off. Other substitutes are available but if you are better with it, it's better to continue because other antidepressant may or may not work adequately.
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User Feedback


FAQs

Q. Can I take Clonotril while taking a dietary supplement?

It depends on what kind of dietary supplement it is. Normally absorption of Clonotril is not affected by food and other vitamins. Consult your doctor before you start taking the medication.

Q. Which medication is best, alprazolam or Clonotril?

Both are equally effective as suggested in different research studies.

Q. What is the difference between clotiazepam and Clonotril?

Clotiazepam is a benzodiazepine which has anxiolytic, sedative and antiepileptic property. It differs from other benzodiazepines (Clonotril) in that the benzene ring is replaced by thiophene ring. Clinical use of clotiazepam is relatively low.

Q. Which medication is best, lorazepam or Clonotril?

Both are equally effective as shown in the research studies.

Q. Which medication is best, diazepam or Clonotril?

Both are equally effective as shown in the research studies.

Q. Can Clonotril affect my sex drive?

There are few reports but it is not so common. Clonotril does not affect the sexual drive in all the patients.

Q. Is Clonotril a narcotic?

No. Clonotril is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Is Clonotril muscle relaxant?

Clonotril is approved for the treatment of anxiety, alcohol withdrawal and epilepsy. Some research studies have shown it has got muscle relaxant properties.

Q. Can I take vitamin B along with Clonotril?

There is no known major interaction found with vitamin B when taken with Clonotril.

Q. Can I take vitamin C along with Clonotril?

There is no known major interaction found with vitamin C when taken with Clonotril.

Q. Can I take Clonotril while I am on hepatitis C treatment?

The treatment of hepatitis C includes many drugs and the side effects depends on which drug you are prescribed.

Q. Can Clonotril cause euphoria?

No. Clonotril does not cause euphoria. It causes sleepiness, dizziness etc.

Q. Can Clonotril get you high?

Clonotril does not make you feel high.

Q. Can Clonotril be replaced with paroxetine?

No. both are different medication. Clonotril is an antianxiety, anticonvulsant drug whereas Paroxetine is an antidepressant medication

Q. Can Clonotril cause rash?

Clonotril is not commonly known to cause a rash but hypersensitive individuals can develop a rash.

Q. Is Clonotril the best choice for restless legs syndrome?

There are other treatment modalities for restless leg syndrome but among these benzodiazepine class of drug Clonotril is most studied drug. It is not approved for restless leg syndrome but used off label.

Q. How is bupropion different than Clonotril?

Bupropion is in the treatment of depression and for smoking cessation. Clonotril is an anti-seizure and anti-anxiety medicine.

Q. Can I take Clonotril along with zolpidem?

No. You should avoid taking these two medications together. They both induce sleep and taking them together can lead to increased sleepiness, decreased concentration, ataxia and abnormal co-ordination.

Q. Which medication is better, Clonotril or clobazam?

Clobazam causes less sedation as compared to Clonotril as seen in few research studies.In few studies, clobazam showed a good retention when given for a longer period whereas Clonotril needs a dose escalation.

Q. Can I take Clonotril along with fluoxetine?

You should avoid taking these two drugs together as they increase side effects like sleepiness, dizziness, drowsiness, confusion, and difficulty concentrating.

Q. Can I take Clonotril while I am also taking antibiotics?

It depends on which antibiotics you are on treatment. Consult your doctor before starting these medications.

Q. Can I take Clonotril along with escitalopram?

You should avoid taking these two drugs together as they increase side effects like sleepiness, dizziness, drowsiness, confusion, and difficulty concentrating.

Q. Which medication is better, Clonotril or nitrazepam?

Both are equally effective as shown in the research studies.

Q. Can I take Clonotril along with paracetamol?

Yes. You can take prescribed doses of paracetamol with Clonotril. Inform your doctor if you have any allergy or liver problems before starting these medications.

Q. Which is stronger Clonotril or oxazepam?

We could not find any direct studies comparing Clonotril with oxazepam. However, oxazepam is an intermediate-acting benzodiazepine with a slow onset of action.

Q. Which medication is better Clonotril or etizolam?

Etizolam is a short acting drug and its structure is a bit different from the benzodiazepines class of drugs. Both are used in inducing sleep and relieving anxiety however it depends.

Q. When does Clonotril expire?

The expiry date of Clonotril is given on the tablet strip and provided by the manufacturer.

Q. How does Clonotril affect the brain?

Clonotril works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Q. Can I take Clonotril along with coffee?

Yes. There are no major interactions known between coffee and Clonotril.

Q. What is the difference between Clonotril and zopiclone?

Clonotril is an anti-siezure, antianxiety medication. Zopiclone is a sedating drug from different class and it is only used for inducing sleep

Q. What is the difference between Clonotril and olanzapine?

Clonotril is an anti-seizure, antianxiety medication. Olanzapine is an atypical antipsychotic medication.

Q. Can Clonotril cause low blood pressure?

Clonotril is not known to cause low blood pressure commonly. It can cause palpitation in some patients.

Q. Can I use Clonotril for sciatica?

No. Clonotril is not a known medication for sciatica. It is an antiseizure, antianxiety medication.

Q. Can tremors be treated with Clonotril?

Clonotril is not an approved drugs for treatment of tremors. However, in some research studies, it has been shown Clonotril is effective

Q. Can I use Clonotril for nausea?

No. Clonotril is not a medication for nausea. It is an antiseizure, antianxiety medication.

Q. Can I use Clonotril for a headache?

No. Clonotril is not a medication for a headache. It is an antiseizure, antianxiety medication.

Q. Can I use Clonotril for vertigo?

No. Clonotril is not a medication for vertigo. It is an antiseizure, antianxiety medication. However, few studies have shown its effectiveness in vertigo.

Q. Can insomnia be treated with Clonotril?

Yes. Though Clonotril is not approved for treatment of insomnia. Clonotril is used off-label for the treatment of sleep disorders.

Q. Can I use Clonotril for depression?

No. Clonotril is not a medication for depression. It is an antiseizure and antianxiety medication. There are the different class of drugs for treating depression.

Q. Can I use Clonotril in pain management?

No. Clonotril is not a medication for management of pain disorders. It is an antiseizure and antianxiety medication. There are the different class of drugs for treating pain. Few studies have failed to prove the effectiveness of Clonotril in pain management.

Q. What is the good time to take Clonotril?

It is given mostly at night as it causes sedation.
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