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Cernos Depot Injection

Testosterone (1000mg)

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Cernos Depot Injection is a medication used to treat male hypogonadism caused by low testosterone levels. It is only prescribed to men with known medical conditions. It helps in restoring the level of testosterone in the male body.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)

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4 ml Injection

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General Information

Contains

Testosterone (1000mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Cernos Depot Injection is administered directly into the skin or muscles, generally under the supervision of a doctor or a nurse. The dose and how often you take the injection depends on your medical condition. Your doctor will decide how much medication you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of Cernos Depot Injection include headache, depression, enlarged breasts, and other injection-site reactions. If these persist or worsen, let your doctor know. They may be able to suggest ways to treat or manage the side effects. Other rare side effects of Cernos Depot Injection include difficulty breathing, frequent erections, and a low sperm count.

Before using Cernos Depot Injection, inform your doctor if you have a history of high blood pressure or any heart-related conditions. Let your doctor also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Your doctor may conduct regular blood tests to monitor testosterone and prostate-specific antigen (PSA) levels.

Uses of Cernos Injection

Treatment of Male hypogonadism

Benefits of Cernos Injection

Treatment of Male hypogonadism
Male hypogonadism is a condition in which the body does not produce enough testosterone (male sex hormone). Cernos Depot Injection injections help improve the level of testosterone in your body. This helps in maintaining better sex life, improve overall physical appearance, gives good mood and boost overall confidence. Cernos Depot Injection also helps in muscle building and development of bones. This treatment has few side effects so it is advisable to always take the injection under a doctor’s supervision only. You should continue taking it as long as it is prescribed even if you feel better.

Side effects of Cernos Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cernos

Injection site reactions (pain, swelling, redness)
Breast tenderness in male
Depression

How to use Cernos Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cernos Injection works

Cernos Depot Injection is similar to testosterone, the natural male hormone. It works by replenishing the deficient testosterone levels in adult men. Lack of testosterone may cause various health problems, including impotence, infertility, low sex drive, tiredness, depressive mood, and bone loss.

Quick tips

Your doctor will administer this injection into a muscle or the skin.
Your doctor may monitor you for 30 minutes after your shot to make sure you do not develop breathing problems or get a severe allergic reaction due to the medicine.
Your doctor may get your blood tests done regularly to monitor red blood cells, liver function, testosterone, and prostate-specific antigen (PSA) levels while taking Cernos Depot Injection.
Inform your doctor if you experience symptoms such as frequent erections, irritability, nervousness, or weight gain after starting treatment with this medicine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cernos Depot Injection. Please consult your doctor.

Pregnancy

UNSAFE

Cernos Depot Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Cernos Depot Injection is not indicated for use in women.

Breast feeding

UNSAFE

Cernos Depot Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Cernos Depot Injection is not indicated for use in women.

Driving

CAUTION

Cernos Depot Injection may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.

Kidney

CAUTION

Cernos Depot Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Cernos Depot Injection is not advisable in patients with severe kidney disease.

Liver

CAUTION

Cernos Depot Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Use of Cernos Depot Injection is not advisable in patients with severe liver disease.

Interaction with drugs

Taking Cernos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Ciclosporin (Oral Route)

Do not consume Ciclosporin with Testosterone. If concurrent use is essential, your doctor may monitor your liver function frequently.

Severe

Ciclosporin (Injection Route)

Do not consume Ciclosporin with Testosterone. If concurrent use is essential, your doctor may monitor your liver function frequently.

Moderate

Gliclazide (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Gliclazide may increase the metabolism of Testosterone.

Moderate

Glibenclamide (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations.

Moderate

Metformin (Oral Route)

If concurrent use is essential, your doctor may monitor your glucose levels frequently and adjust the doses as per the observations. Testosterone may reduce the efficacy of Metformin.

Frequently asked questions

What is Cernos Depot Injection, and what is it used for?

Cernos Depot Injection is a medicine that contains a synthetic form of the male sex hormone, testosterone. It is used in the treatment of male hypogonadism (a condition in which the body does not produce enough testosterone).

Can Cernos Depot Injection be used for bodybuilding purposes?

No, Cernos Depot Injection should not be used to enhance muscle mass or physical ability in healthy individuals, as improper use may lead to harmful effects. Additionally, external administration of Cernos Depot Injection in healthy individuals can disrupt hormonal balance.

How long does it take for Cernos Depot Injection to show its effects?

While some effects of Cernos Depot Injection may become noticeable within 3 weeks, others may take longer. For instance, an increase in sexual interest may appear after 3 weeks, whereas changes in erections or ejaculation may take up to 6 months.

Who should not take Cernos Depot Injection?

Cernos Depot Injection should not be given to men with breast cancer, prostate cancer, and kidney disease. It should be avoided in patients who had or presently have liver cancer and in those who have increased levels of calcium in the blood. It should not be used by females, children below 18 years, and elderly patients more than 65 years of age.

What are the major health risks associated with Cernos Depot Injection therapy?

The major health risks associated with the use of Cernos Depot Injection in men are heart attack, stroke, and prostatic carcinoma.

Will there be a problem if I am taking warfarin and have started Cernos Depot Injection?

You should get blood tests done more frequently to check your bleeding time (time taken to stop bleeding) when you are taking warfarin along with Cernos Depot Injection, especially when starting and stopping Cernos Depot Injection. Talk to your doctor for advice.

Can Cernos Depot Injection have any harmful effects if I am diabetic?

Cernos Depot Injection may decrease blood glucose levels, and therefore, the dose of antidiabetic medicines should be reduced. Consult your doctor for advice.

Fact Box

Chemical Class

Androgen derivative

Habit Forming

Therapeutic Class

SEX STIMULANTS REJUVENATORS

Action Class

Androgens

Related lab tests

Follicle Stimulating Hormone

Testosterone Free

Testosterone Total

References

Snyder PJ. Androgens. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1195-206.
Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 719-22.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1335-37.
Testosterone [Patient Information Leaflet]. Jena, Germany: Ever Pharma Jena; 2018. [Accessed 03 Apr. 2019] (online) Available from:
Testosterone Enantate [Patient Information Leaflet]. Berlin, Germany: Bayer AG; 2017. [Accessed 18 Jun. 2019] (online) Available from:
Testosterone Cypionate [Prescribing Information]. Portugal: Hikma Pharmaceuticals; 2019. [Accessed 03 Feb. 2025] (online) Available from:
Testosterone [Prescribing Information]. Princeton, NJ: Slayback Pharma LLC.; 2022. [Accessed 03 Feb. 2025] (online) Available from:

User feedback

Patients taking Cernos Depot Injection

Once A Month

100%

What are you using Cernos Injection for?

Male hypogonadism

93%

Others

How much was the improvement?

Excellent

40%

Average

33%

Poor

28%

What were the side-effects while using Cernos Depot Injection?

Injection site pain

47%

Breast pain

12%

Leg pain

No Side Effect

Hot flashes

How do you take Cernos Injection?

With or without food

63%

With food

26%

Empty stomach

11%

Please rate Cernos Depot Injection on price

Expensive

49%

Average

35%

Not Expensive

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cernos Depot Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Cernos Depot Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Cernos Injection

Benefits of Cernos Injection

Side effects of Cernos Injection

How to use Cernos Injection

How Cernos Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ciclosporin (Oral Route)

Ciclosporin (Injection Route)

Gliclazide (Oral Route)

Glibenclamide (Oral Route)

Metformin (Oral Route)

Frequently asked questions

What is Cernos Depot Injection, and what is it used for?

Can Cernos Depot Injection be used for bodybuilding purposes?

How long does it take for Cernos Depot Injection to show its effects?

Who should not take Cernos Depot Injection?

What are the major health risks associated with Cernos Depot Injection therapy?

Will there be a problem if I am taking warfarin and have started Cernos Depot Injection?

Can Cernos Depot Injection have any harmful effects if I am diabetic?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Follicle Stimulating Hormone

Testosterone Free

Testosterone Total

References

User feedback

Patients taking Cernos Depot Injection

What are you using Cernos Injection for?

How much was the improvement?

What were the side-effects while using Cernos Depot Injection?

How do you take Cernos Injection?

Please rate Cernos Depot Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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