Celgem 1000mg Injection

Gemcitabine (1000mg)

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Celgem 1000mg Injection is used in the treatment of non-small cell lung cancer, breast cancer, pancreatic cancer, urinary bladder cancer, and ovarian cancer.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)

₹4770 MRP ₹5237.039% off

Gurgaon

Celgem 1000mg Injection is currently sold out

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Cytogem 1000mg Injection

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Celgem 1000mg Injection

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Same composition

Cytogem 1000mg Injection

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Gemcitabine (1000mg)

by Dr Reddy's Laboratories Ltd

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General Information

Contains

Gemcitabine (1000mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Celgem 1000mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, hair loss and low blood platelets. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Celgem Injection

Benefits of Celgem Injection

Breast cancer
Celgem 1000mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Celgem 1000mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

Urinary bladder cancer
Urinary bladder cancer is the type of cancer that develops in the bladder, usually in older adults. The most common symptom of this cancer is blood in the urine. Celgem 1000mg Injection is used in combination with other medicines such as cisplatin to treat urinary bladder cancer that has advanced to later stages or even spread to other regions of the body (metastasized). It is a highly effective medicine and also prevents the cancer from returning. However, you must discuss the risks and benefits of this medicine before starting your treatment.

Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Celgem 1000mg Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.

Ovarian cancer
Ovarian cancer is a cancer that begins in the female organs that produce eggs (ovaries). This type of cancer is usually detected very late and can be fatal too. It usually spreads to the pelvis and stomach. Celgem 1000mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective medicine but has some side effects that may be bothersome. Consult your doctor to know about ways that can help you avoid these side effects.

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Celgem 1000mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Celgem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Celgem

Loss of appetite
Nausea
Vomiting
Hair loss
Low blood platelets
Allergic reaction
Breathlessness
Decreased white blood cell count
Increased liver enzymes
Anemia (low number of red blood cells)
Flu-like symptoms
Blood in urine
Skin rash
Protein in urine

How to use Celgem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Celgem Injection works

Celgem 1000mg Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

All substitutes for Celgem 1000mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Celgem 1000mg Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Celgem 1000mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Celgem 1000mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Celgem 1000mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Celgem 1000mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Kidney function tests are advised before taking this medicine and regular monitoring is also recommended after the treatment.

Liver

CAUTION

Celgem 1000mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Celgem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before and until 24 hours after taking Gemcitabine.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Gemcitabine may reduce efficacy of Cholera Vaccine (Inactivated). Gemcitabine may reduce efficacy of Cholera Vaccine (Inactivated).

Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Gemcitabine may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). Gemcitabine may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Gemcitabine may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Gemcitabine may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Natalizumab (Injection Route)

Do not consume Natalizumab with Gemcitabine. If concurrent use is essential, your doctor may monitor you for signs of infection.

Frequently asked questions

What is Celgem 1000mg Injection used for?

Celgem 1000mg Injection is a chemotherapy medicine used for treating several types of cancer, including lung cancer, pancreatic cancer, breast cancer, ovarian cancer, and bladder cancer.

Is Celgem 1000mg Injection safe for everyone with cancer?

Celgem 1000mg Injection is not suitable for everyone. It may not be recommended if you have very low blood cell counts, certain liver or kidney problems, or severe infections. Your doctor checks your blood counts before each dose to ensure the treatment is safe for you.

Why do I need frequent blood tests while on Celgem 1000mg Injection?

You need frequent blood tests because Celgem 1000mg Injection can lower important blood cells such as white cells, red cells, and platelets. These tests help your doctor see if it is safe to continue treatment and prevent complications like infections or bleeding.

Can Celgem 1000mg Injection cause serious infections?

Yes, Celgem 1000mg Injection can weaken your immune system, making infections more likely and sometimes serious. If you get a fever, chills, sore throat, cough, or feel unusually weak, you should contact your doctor immediately.

What serious side effects should I watch out for with Celgem 1000mg Injection?

Serious side effects of Celgem 1000mg Injection can include trouble breathing, sudden swelling, very low blood counts, severe tiredness, liver problems, and kidney issues. Another rare but serious risk is a condition called capillary leak syndrome, which causes sudden swelling, low blood pressure, and breathing problems. These require immediate medical attention.

Can Celgem 1000mg Injection affect my lungs?

Yes. Celgem 1000mg Injection can sometimes lead to lung problems, including inflammation or breathing difficulty. If you suddenly develop shortness of breath, worsening cough, or chest tightness, get medical help right away.

Is swelling or fluid retention a known risk with Celgem 1000mg Injection?

Yes. Celgem 1000mg Injection can cause swelling in the legs, arms, or face due to fluid buildup. Rarely, it can lead to serious conditions like capillary leak syndrome. If you notice rapid swelling, sudden weight gain, or difficulty breathing, seek urgent care.

Can Celgem 1000mg Injection cause liver or kidney problems?

Celgem 1000mg Injection can sometimes affect the liver and kidneys. Your doctor checks your liver enzymes and kidney function regularly. Signs like yellowing of the skin, dark urine, or reduced urination should be reported right away.

Can Celgem 1000mg Injection interact with radiation treatment?

Yes. Celgem 1000mg Injection can increase the risk of radiation-related side effects, including skin reactions or lung problems, especially if radiation is given at the same time, or shortly before/after treatment.

What emergency symptoms should make me stop Celgem 1000mg Injection and seek help immediately?

During Celgem 1000mg Injection treatment, you should get urgent medical care if you experience severe shortness of breath, chest pain, sudden swelling, unexplained bruising or bleeding, very high fever, severe fatigue, or signs of allergic reaction like rash, or swelling of the face.

Is Celgem 1000mg Injection safe if I have a history of heart problems?

Celgem 1000mg Injection is generally used with caution in people with heart conditions, as it may rarely cause heart-related issues such as low blood pressure or fluid in the lungs. Tell your doctor if you have heart disease so they can monitor you closely.

Fact Box

Chemical Class

Pyrimidine 2'- deoxyribonucleosides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1700-701.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 947-48.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 617-18.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

User feedback

What are you using Celgem Injection for?

Ovarian cancer

100%

How much was the improvement?

Poor

100%

What were the side-effects while using Celgem 1000mg Injection?

Low blood platelets

25%

Loss of appetite

25%

Hair loss

25%

Vomiting

25%

How do you take Celgem Injection?

With food

100%

Please rate Celgem 1000mg Injection on price

Not Expensive

67%

Average

33%

Want to know more

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Celgem 1000mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Celgem Injection

Benefits of Celgem Injection

Side effects of Celgem Injection

How to use Celgem Injection

How Celgem Injection works

All substitutes for Celgem 1000mg Injection

Cytogem 1000mg Injection

Gemchem 1000mg Injection

Mygem 1000mg Injection

Gembine 1000mg Injection

Lifogem 1000mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Filgrastim (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Natalizumab (Injection Route)

Frequently asked questions

What is Celgem 1000mg Injection used for?

Is Celgem 1000mg Injection safe for everyone with cancer?

Why do I need frequent blood tests while on Celgem 1000mg Injection?

Can Celgem 1000mg Injection cause serious infections?

What serious side effects should I watch out for with Celgem 1000mg Injection?

Can Celgem 1000mg Injection affect my lungs?

Is swelling or fluid retention a known risk with Celgem 1000mg Injection?

Can Celgem 1000mg Injection cause liver or kidney problems?

Can Celgem 1000mg Injection interact with radiation treatment?

What emergency symptoms should make me stop Celgem 1000mg Injection and seek help immediately?

Is Celgem 1000mg Injection safe if I have a history of heart problems?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

References

User feedback

What are you using Celgem Injection for?

How much was the improvement?

What were the side-effects while using Celgem 1000mg Injection?

How do you take Celgem Injection?

Please rate Celgem 1000mg Injection on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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