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Cazanat 60 Tablet

Cabozantinib (60mg)

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Cazanat 60 Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver and kidney cancer.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 04 Oct 2026 | 01:03 AM (IST)

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Cazanat 60 Tablet

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Cabdual 60mg Tablet

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Cabozantinib (60mg)

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General Information

Contains

Cabozantinib (60mg)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Cazanat 60 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. Take it exactly as advised by the doctor. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, and diarrhea are some of the common side effects of Cazanat 60 Tablet. It might cause high blood pressure, so the doctor may ask you for a regular check up of blood pressure. You must inform your doctor if you notice a severe skin reaction, such as skin rash or any pain, swelling, and redness of your hands and feet.

Before taking Cazanat 60 Tablet, tell your doctor if you have heart disease, liver or kidney problems, or high blood pressure. Many other medicines can affect, or be affected by, this medicine, so let your healthcare team know about all the medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during the treatment with this drug is important to avoid pregnancy.

Uses of Cazanat Tablet

Benefits of Cazanat Tablet

Treatment of Kidney cancer
This medicine helps treat kidney cancer by slowing or stopping the growth and spread of cancer cells. It can help control the disease, reduce the cancer burden, and delay further progression, which may help patients manage the condition for longer.

Treatment of Liver cancer
Liver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms during the early stages of the cancer but as the disease advances to later stages, symptoms such as weight loss, stomach pain, vomiting, and yellowed skin may appear. Cazanat 60 Tablet kills the cancer cells and prevents further growth and spread of the cancer to other unaffected areas. Drinking alcohol or smoking can worsen your condition and hinder your recovery, so avoid their use.

Side effects of Cazanat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cazanat

Diarrhea
Nausea
Fatigue
Weight loss
High blood pressure
Constipation

How to use Cazanat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cazanat 60 Tablet is to be taken on an empty stomach.

How Cazanat Tablet works

Cazanat 60 Tablet works by blocking certain signals that cancer cells need to grow, multiply, and survive. It interferes with these signals; it helps slow down the growth and spread of cancer cells and helps control the progression of kidney cancer.

All substitutes for Cazanat 60 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Cazanat 60 Tablet is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cazanat 60 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Cazanat 60 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Cazanat 60 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Cazanat 60 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Cazanat 60 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Cazanat 60 Tablet in patients with liver disease.
Dose adjustment may be needed. It should not be recommended in severe renal disease.

Interaction with drugs

Taking Cazanat with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Hydroxychloroquine (Oral Route)

Do not consume Hydroxychloroquine with Cabozantinib.

Life-threatening

Phenindione (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.

Life-threatening

Warfarin (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. Your doctor may frequently monitor your blood clotting time.

Life-threatening

Sevoflurane (Oral Route)

Do not consume Sevoflurane with Cabozantinib.

Life-threatening

Lenvatinib (Oral Route)

Do not consume Lenvatinib with Cabozantinib.

Frequently asked questions

What is Cazanat 60 Tablet used for?

Cazanat 60 Tablet is used to treat certain cancers, such as kidney cancer (advanced renal cell carcinoma), liver cancer after sorafenib, and thyroid cancer that has spread and no longer responds to radioactive iodine. In some cases, a doctor can also use this medicine for some neuroendocrine tumors (pancreas and extra‑pancreatic) after other treatments.

Who should not take Cazanat 60 Tablet?

There are no absolute “do not use” conditions known with Cazanat 60 Tablet, but people with a recent serious bleed (hemorrhage) must not start it, and your doctor may avoid it in severe liver disease (Child‑Pugh C) because it has not been studied and can raise risks.

During Cazanat 60 Tablet treatment, what warning signs mean I should get urgent help?

During Cazanat 60 Tablet treatment, call your doctor immediately if you experience coughing/vomiting blood, or black stools (bleeding). Sudden severe stomach pain or fever (perforation), chest pain or sudden shortness of breath (clot/heart attack), severe headache or confusion (hypertensive crisis/RPLS), severe or nonstop diarrhea, yellow eyes/skin (liver injury), sudden leg swelling, or new/worse jaw pain or mouth sores that will not heal (jaw bone problem).

Will Cazanat 60 Tablet affect surgery or dental work?

Yes. Your doctor may stop Cazanat 60 Tablet at least 3 weeks before planned surgery (including dental surgery) and will not restart for at least 2 weeks after major surgery and until wounds are well‑healed, because of bleeding and poor wound healing risks.

What health conditions need extra care during Cazanat 60 Tablet treatment?

During Cazanat 60 Tablet treatment, tell your doctor if you have high blood pressure (hypertension), bleeding risks, stomach or bowel disease, recent surgery, liver disease, kidney issues, jaw/dental problems, thyroid disease, or a history of blood clots or heart attack, because you may need monitoring, dose changes, or to avoid treatment in some cases.

Can Cazanat 60 Tablet harm a baby or affect fertility?

Yes. Cazanat 60 Tablet can harm an unborn baby. Females who can become pregnant should use effective birth control during treatment and for 4 months after the last dose. Breastfeeding should not happen during treatment and for 4 months after the last dose. It may reduce fertility in males and females, making it harder to have a baby.

What serious side effects of Cazanat 60 Tablet happen most often?

The common serious side effects of Cazanat 60 Tablet include severe diarrhea, severe high blood pressure, hand‑foot skin reaction (painful redness/blisters on palms/soles), liver test increases (especially with nivolumab, lowercase as drug component), blood clots, and bleeding. Your team may pause treatment and restart at a lower dose, or stop permanently if severe.

Fact Box

Chemical Class

Diarylethers

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Alpha-fetoprotein (AFP) L3 Fraction

Complete Blood Count

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India

Lab tests offered by us

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Cazanat 60 Tablet

Cazanat 60 Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Cazanat Tablet

Benefits of Cazanat Tablet

Side effects of Cazanat Tablet

How to use Cazanat Tablet

How Cazanat Tablet works

All substitutes for Cazanat 60 Tablet

Kabonib 60mg Tablet

Cabozanib 60 Tablet

Cabdual 60mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Hydroxychloroquine (Oral Route)

Phenindione (Oral Route)

Warfarin (Oral Route)

Sevoflurane (Oral Route)

Lenvatinib (Oral Route)

Frequently asked questions

What is Cazanat 60 Tablet used for?

Who should not take Cazanat 60 Tablet?

During Cazanat 60 Tablet treatment, what warning signs mean I should get urgent help?

Will Cazanat 60 Tablet affect surgery or dental work?

What health conditions need extra care during Cazanat 60 Tablet treatment?

Can Cazanat 60 Tablet harm a baby or affect fertility?

What serious side effects of Cazanat 60 Tablet happen most often?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Alpha-fetoprotein (AFP) L3 Fraction

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests