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Casponex 50mg Injection

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 14 Apr 2026 | 01:19 PM (IST)
Casponex 50mg Injection is an antifungal medication. It is used in the treatment of severe fungal infections. It kills the fungi that cause these infections and thus provides relief.
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General Information

Contains

Caspofungin (50mg)

Marketer

Bharat Serums & Vaccines Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Casponex 50mg Injection image
Casponex 50mg Injection image

Product introduction

Casponex 50mg Injection is administered as an injection by a healthcare professional. Kindly do not self-administer. Do not skip any doses and finish the full course of treatment even if you feel better. Your doctor may monitor your liver function regularly during treatment.

Casponex 50mg Injection may lead to a few common side effects like rash, decreased potassium level in the blood, fever, increased liver enzymes, chills, and diarrhea. You may also notice some injection site reactions like pain, swelling, or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive, or breastfeeding.

Uses of Casponex Injection

  • Severe fungal infections

Benefits of Casponex Injection

Severe fungal infections
Severe fungal infections can affect internal organs and are often life-threatening, especially in people with weakened immune systems. Casponex 50mg Injection is used to treat these serious infections by stopping the growth of the fungus. It helps control the infection effectively, supports faster recovery, and lowers the risk of complications.

Side effects of Casponex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Casponex
  • Chills
  • Decreased potassium level in blood
  • Diarrhea
  • Fever
  • Increased alkaline phosphatase level in blood
  • Increased liver enzymes
  • Rash

How to use Casponex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Casponex Injection works

Casponex 50mg Injection works by targeting the protective outer wall of fungal cells, which is essential for their strength and survival. It blocks an enzyme called β-(1,3)-D-glucan synthase, responsible for making a key component of this wall. When this enzyme is blocked, the fungal cell wall becomes weak and leaky, causing the fungus to break apart and die. This helps the body fight off severe fungal infections more effectively and prevents their spread.

Quick tips

  • Casponex 50mg Injection is given as a slow drip into vein (IV infusion) under the supervision of a doctor.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
  • Casponex 50mg Injection is given as a slow drip into vein (IV infusion) under the supervision of a doctor.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop abdominal pain, loss of appetite, darkened urine or yellowing of the eyes or skin (jaundice).
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Casponex 50mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Casponex 50mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Casponex 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Casponex 50mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Casponex 50mg Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CAUTION
Casponex 50mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Limited information is available on the use of Casponex 50mg Injection in patients with the severe liver disease.

Interaction with drugs

Taking Casponex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations. Caspofungin may reduce blood levels of Tacrolimus.
Moderate

Tinzaparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Bemiparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Carbamazepine (Oral Route)

Careful consideration is advised when taking Caspofungin with Carbamazepine, your doctor may adjust the doses as per the observations. Carbamazepine may reduce blood levels of Caspofungin.
Moderate

Certoparin (Injection Route)

If concurrent use is essential, watch out for symptoms such as fatigue, nausea, loss of appetite, dark urine or jaundice and consult your doctor if you experience them. They may adjust the doses as per the observations.

Frequently asked questions

Casponex 50mg Injection is used to treat serious fungal as well as yeast infections in the blood, stomach, lungs, and food pipe (esophagus).
Yes, Casponex 50mg Injection is an antifungal antibiotic. It kills the fungi and yeast causing serious infections and helps in clearing the infection.
Casponex 50mg Injection should be administered as an injection into a vein under the supervision of a trained healthcare professional or a doctor only usually once a day. It should be injected slowly over 1 hour and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Casponex 50mg Injection.
Casponex 50mg Injection targets an essential component of the outermost layer (cell wall) of the fungus, called beta-(1,3)-D-glucan. This component is present in the Aspergillus species and Candida species but not present in mammalian cells. Casponex 50mg Injection stops the synthesis of this component and this kills the fungus, inhibits further growth, thereby clearing the infection.
Casponex 50mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Casponex 50mg Injection too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Echinocandins

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Echinocandins

References

  1. Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1583-84.
  2. Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 216-17.
  4. Caspofungin. White House Station, New Jersey: Merck & Co.; 2001. [Accessed 29 Mar. 2019] (online) Available from:
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
  6. Hangzhou, Zhejiang: Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.; 2025 [Accessed 03 Nov. 2025] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Vendor Details

Country of origin: India
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