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Carfizome 60 Injection

Carfilzomib (60mg)

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Authenticity Assured

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required

Cold stored

Stored between 2-8°C

Carfizome 60 Injection is an anticancer medicine used to treat multiple myeloma in adults who have previously received treatment. It works by interfering with the normal breakdown of proteins inside cancer cells, causing them to die and helping slow or stop cancer growth.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 27 Oct 2026 | 01:01 AM (IST)

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Carfilzomib (60mg)

by MSN Laboratories

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General Information

Contains

Carfilzomib (60mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Carfizome 60 Injection is given as an infusion into a vein under the supervision of a doctor or healthcare professional. Your doctor will determine the appropriate dose and treatment schedule based on your condition, previous treatments, and response to the medicine. The dose may be adjusted depending on the side effects you experience.

Common side effects of Carfizome 60 Injection include fatigue, nausea, fever, diarrhea, shortness of breath, and decreased blood cell counts. This medicine may also cause serious side effects, including heart problems, kidney problems, high blood pressure, and infusion-related reactions. Inform your doctor immediately if you experience chest pain, difficulty breathing, swelling of the legs, fever, chills, or unusual bleeding or bruising. Your doctor will monitor your blood cell counts, kidney and liver function, blood pressure, and heart health during treatment.

Before receiving Carfizome 60 Injection, inform your doctor if you have heart disease, high blood pressure, kidney or liver problems, or a history of blood clots. Your doctor may recommend adequate fluid intake before treatment to reduce the risk of certain complications, but the amount of fluid should be carefully managed, particularly if you have heart problems.

Inform your doctor about all medicines you are taking, including herbal supplements. Carfizome 60 Injection may harm an unborn baby and should be avoided during pregnancy. Effective contraception is recommended during treatment and for a specified period after the last dose. Breastfeeding should also be avoided during treatment and for the recommended period after the last dose.

Uses of Carfizome Injection

Treatment of Multiple myeloma

Benefits of Carfizome Injection

Treatment of Multiple myeloma
Multiple myeloma is a type of blood cancer that affects plasma cells, a type of white blood cell found in the bone marrow. Carfizome 60 Injection is an anticancer medicine that helps treat multiple myeloma in adults whose disease has returned or has not responded adequately to previous treatment. It helps reduce the number of cancer cells and control disease progression. It may be used alone or in combination with other anticancer medicines, depending on previous treatments and the patient’s condition.

Side effects of Carfizome Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Carfizome

Fatigue
Anemia (low number of red blood cells)
Nausea
Low blood platelets
Fever
Breathlessness
Diarrhea
Headache
Cough
Peripheral edema
Edema (swelling)

How to use Carfizome Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Carfizome Injection works

Carfizome 60 Injection is an anticancer medicine that works by blocking the breakdown of proteins inside cancer cells. This causes unwanted proteins to build up inside these cells, eventually leading to their death. This helps slow or stop the growth of cancer cells.

All substitutes for Carfizome 60 Injection

For information purposes only. Consult a doctor before taking any medicine.

Kyfil 60mg Injection

by MSN Laboratories

₹13500/injection

44% costlier

Quick tips

Carfizome 60 Injection is given as an infusion into the vein (IV infusion) under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelet count, liver function, and kidney function during treatment.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and a sore throat.
Let your doctor know if you notice chest pains, shortness of breath, difficulty breathing, dizziness, and swelling of feet.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Carfizome 60 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Carfizome 60 Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Carfizome 60 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Carfizome 60 Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Carfizome 60 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Carfizome 60 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Carfizome with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Colchicine (Oral Route)

Concomitant use may increase the risk of Colchicine poisoning.

Moderate

Digoxin (Injection Route)

Concomitant use may increase the risk of Digoxin poisoning.

Mild

Interferon Alpha 2A (Injection Route)

If concurrent use is essential, your doctor may closely monitor functioning of nervous system.

Frequently asked questions

Is Carfizome 60 Injection right for me?

Carfizome 60 Injection in combination with other medications is for patients with relapsed multiple myeloma (multiple myeloma that has returned) and for refractory multiple myeloma (multiple myeloma that no longer responds to treatment). Talk to your doctor in case of any doubts.

How is Carfizome 60 Injection administered?

Carfizome 60 Injection is given as an intravenous (IV) infusion. This is a way to put fluids, including medicine, into your bloodstream through a vein.

How often will I be given Carfizome 60 Injection?

You may receive this injection in treatment cycles. Each cycle lasts 4 weeks. The cycle includes days when you are given treatment and days when you do not have treatment (rest periods). You will usually have Carfizome 60 Injection 2 days a week for 3 weeks. In week 4 you do not have treatment. Your doctor will decide your treatment plan depending on what will work best for you.

I am experiencing nausea and extreme tiredness. Is this due to Carfizome 60 Injection?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

Does Carfizome 60 Injection reduce immunity?

After the start of the treatment with this medicine, your platelet count might become low. As a result, you may be at risk of infection. It is therefore advisable to avoid crowds or people with colds and infections. Wash your hands often and always after using the bathroom.

When should I seek a doctor’s advice?

You should contact your doctor immediately if you develop shortness of breath, prolonged, unusual, or excessive bleeding, yellowing of the skin and/or eyes (jaundice), severe headache, confusion, seizures, or loss of sight.

Can Carfizome 60 Injection be used during pregnancy?

Carfizome 60 Injection can cause harm to the unborn baby when given to a pregnant woman. Women should use effective contraception during treatment with this medicine and for 6 months following the final dose. Men should use effective contraception during treatment and for 3 months following the final dose.

Can Carfizome 60 Injection be used during breastfeeding?

Because of the potential for serious adverse reactions in the breastfed child, advise women not to breastfeed during treatment with Carfizome 60 Injection and for 2 weeks after treatment.

What are some of the precautions to be taken while on treatment with Carfizome 60 Injection?

You might get dehydrated while on treatment with Carfizome 60 Injection, so it is advisable to increase your fluid intake. This medicine might make you feel dizzy so it is advisable not to drive or operate any machinery. Avoid sun exposure and wear SPF 15 (or higher) sunblock and protective clothing in order to prevent rashes.

Fact Box

Chemical Class

Oligopeptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Proteasome Inhibitors

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 209.
Carfilzomib. Netherlands: Amgen Europe B.V.; 2015 [revised Sep. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
Carfilzomib. South San Francisco, California: Onyx Pharmaceuticals; 2012. [Accessed 26 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Carfilzomib. Thousand Oaks, U.S.A.: Onyx Pharmaceuticals, Inc.; [Accessed 16 Sep. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

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Carfizome 60 Injection

Carfizome 60 Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Carfizome Injection

Benefits of Carfizome Injection

Side effects of Carfizome Injection

How to use Carfizome Injection

How Carfizome Injection works

All substitutes for Carfizome 60 Injection

Kyfil 60mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Colchicine (Oral Route)

Digoxin (Injection Route)

Interferon Alpha 2A (Injection Route)

Frequently asked questions

Is Carfizome 60 Injection right for me?

How is Carfizome 60 Injection administered?

How often will I be given Carfizome 60 Injection?

I am experiencing nausea and extreme tiredness. Is this due to Carfizome 60 Injection?

Does Carfizome 60 Injection reduce immunity?

When should I seek a doctor’s advice?

Can Carfizome 60 Injection be used during pregnancy?

Can Carfizome 60 Injection be used during breastfeeding?

What are some of the precautions to be taken while on treatment with Carfizome 60 Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Albumin/Globulin Ratio, Serum

Calcium

Complete Blood Count

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests