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Capecitaris 500mg Tablet

Capecitabine (500mg)

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Capecitaris 500mg Tablet is an anticancer medicine used in the treatment of breast and colorectal (colon and rectal) cancers. It may also be used to treat other types of cancer, as determined by the doctor. It can be used alone or in combination with other anticancer medicines as part of chemotherapy.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 15 Oct 2026 | 11:12 PM (IST)

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General Information

Contains

Capecitabine (500mg)

Marketer

Daris Biocare

Storage

Store below 30°C

The content is shown in English

Product introduction

Capecitaris 500mg Tablet should be taken within 30 minutes after a meal. Your doctor will decide the appropriate dose and treatment schedule based on your condition and response to treatment. Take it exactly as prescribed. Your doctor may monitor your response to treatment through regular checkups and tests. Do not stop taking this medicine unless your doctor advises you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, fatigue, and hand-foot syndrome (redness, swelling, or pain in the palms and soles). It may also lower your blood cell counts, increasing the risk of infections, bleeding, or anemia. Your doctor may recommend regular blood tests to monitor your blood cell counts, liver function, and kidney function during treatment.

Before taking this medicine, inform your doctor if you have kidney, liver, or heart problems, or a known deficiency of an enzyme called dihydropyrimidine dehydrogenase (DPD). Tell your doctor about all other medicines you are taking, as some may interact with Capecitaris 500mg Tablet and cause serious side effects. This medicine can harm an unborn baby and should be avoided during pregnancy. Breastfeeding should also be avoided during treatment. Both men and women should follow their doctor's advice regarding effective contraception during treatment and for the recommended period afterward.

Uses of Capecitaris Tablet

Benefits of Capecitaris Tablet

Treatment of Breast cancer
Capecitaris 500mg Tablet is used to treat breast cancer, especially when other treatments have not worked. It helps slow cancer cell growth, shrink tumors, and may reduce the chance of cancer spreading further.

Treatment of Cancer of colon and rectum
In colon and rectal cancer, Capecitaris 500mg Tablet is used to control disease progression, shrink tumors, and improve the effectiveness of surgery or radiation. It can also reduce the risk of the cancer coming back after treatment.

Side effects of Capecitaris Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Capecitaris

Anemia (low number of red blood cells)
Nausea
Fatigue
Abdominal pain
Increased bilirubin in the blood
Dermatitis
Hair loss
Palmar-plantar erythrodysesthesia syndrome
Diarrhea

How to use Capecitaris Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Capecitaris 500mg Tablet should be taken with or after food.

How Capecitaris Tablet works

Capecitaris 500mg Tablet is an anticancer medication. Inside the body, this medicine gets converted into 5-fluorouracil (a chemical). This chemical hampers the synthesis of genetic materials (RNA and DNA) in the cancer cells, thereby interfering with their growth. This slows down the growth of cancer cells and eventually kills them.

All substitutes for Capecitaris 500mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Capecitaris 500mg Tablet is used alone or in combination with other medicines for the treatment of colon, rectum or breast cancers.
It should be taken within 30 minutes after eating a meal.
The dose and the number of treatment cycles needed will depend on the type and stage of cancer that is being treated.
It may cause dizziness and tiredness. Don't drive or do anything requiring concentration until you know how it affects you.
Do not take it if you are pregnant or breastfeeding.
Your doctor may regularly monitor your blood cells during treatment with this medicine. Inform your doctor immediately if you notice signs of infection such as fever, sore throat, rash, or severe diarrhea.
Inform your doctor immediately if you start to have side effects such as diarrhea, vomiting, nausea, mouth sores, chest pain or loss of appetite.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Capecitaris 500mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Capecitaris 500mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Capecitaris 500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Capecitaris 500mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Capecitaris 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Capecitaris 500mg Tablet is not recommended in patients with severe kidney disease.

Liver

CAUTION

Capecitaris 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Capecitaris 500mg Tablet is not recommended in patients with severe kidney disease.

Interaction with drugs

Taking Capecitaris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Pegfilgrastim (Injection Route)

Do not consume Capecitabine from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor.

Life-threatening

Sargramostim (Injection Route)

Do not consume Capecitabine from 1 day before until 1 day after taking Sargramostim. Please consult your doctor.

Life-threatening

Lenograstim (Injection Route)

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy.

Life-threatening

Molgramostim (Injection Route)

Do not consume Capecitabine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor.

Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Capecitabine.

Frequently asked questions

Should Capecitaris 500mg Tablet be taken with or without food?

Take Capecitaris 500mg Tablet within 30 minutes after finishing a meal. Swallow it whole (do not cut or crush) with water. Consult your doctor if you cannot take the whole tablet. If Capecitaris 500mg Tablet needs to be crushed or cut, it should be done by a trained professional using appropriate equipment and safety procedures.

Do I need to use a birth control method while using Capecitaris 500mg Tablet?

Yes, birth control methods are a must while using Capecitaris 500mg Tablet, as this medicine may harm your unborn child. Females should continue using these methods for 6 months after the final dose. On the other hand, men using these medicines whose partners can become pregnant should use effective birth control during treatment and for 3 months after the final dose.

How long do I need to take Capecitaris 500mg Tablet?

The duration of treatment with Capecitaris 500mg Tablet depends on the nature of your illness and individual response to treatment. Usually, it is given as a series of treatment cycles; each of these cycles lasts for 21 days. Capecitaris 500mg Tablet is given for 14 days, followed by a rest period of 7 days. You should continue taking this medicine for the time prescribed by the doctor.

Does Capecitaris 500mg Tablet make you tired?

Yes, Capecitaris 500mg Tablet may make you tired, and you may also feel weak, as these are the most common side effects of the medicine. Hence, use of Capecitaris 500mg Tablet may affect your ability to drive or operate machinery.

What is the most important information that I should know about Capecitaris 500mg Tablet?

It is important to know that Capecitaris 500mg Tablet can interfere with the working of blood thinners like warfarin. This type of interference can cause a change in the rate of clot formation and can cause bleeding that can even lead to death. The risk is higher for cancer patients, especially those who are over 60 years of age. Seek immediate medical help if you experience symptoms like unusual bleeding, vomiting or spitting up blood or brown material that resembles coffee grounds, bloody or black, tarry stools, blood in urine, red or dark-brown urine, or easy bruising.

What kind of drug is Capecitaris 500mg Tablet?

Capecitaris 500mg Tablet is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Capecitaris 500mg Tablet is classified as an "antimetabolite." Capecitaris 500mg Tablet itself is not a cytostatic medicine; it gets converted into an active anti-cancer medicine (more in tumour tissue than in normal tissue) only after getting absorbed by the body.

Do I need to get any tests done while on Capecitaris 500mg Tablet?

The doctor will check you regularly while you are taking Capecitaris 500mg Tablet to monitor side effects and your response to therapy. You may need to get your blood test done as advised by the doctor to monitor your complete blood count (CBC) as well as the function of your kidneys and liver.

Fact Box

Chemical Class

5- deoxyribonucleosides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1698.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 947.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 191.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Capecitabine. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Fresenius Kabi: Capecitabine [Product Information]. [Accessed 12 Jun, 2023] (online) Available from:
Capecitabine [Product Information]. South San Francisco, CA: Genentech, Inc.; 2024. [Accessed 12 Jun, 2023] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Daris Biocare
Address: #95, 1st Street, Muniappa Nagar,Nerkundram, Chennai-600107, Tamilnadu

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Anti Neoplastics

Antimetabolites

Capecitaris 500mg Tablet

Capecitaris 500mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Capecitaris Tablet

Benefits of Capecitaris Tablet

Side effects of Capecitaris Tablet

How to use Capecitaris Tablet

How Capecitaris Tablet works

All substitutes for Capecitaris 500mg Tablet

Cacit 500mg Tablet

Capsy 500mg Tablet

Capetero 500mg Tablet

Capiibine Tablet

Capegard 500 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Pegfilgrastim (Injection Route)

Sargramostim (Injection Route)

Lenograstim (Injection Route)

Molgramostim (Injection Route)

Natalizumab (Injection Route)

Frequently asked questions

Should Capecitaris 500mg Tablet be taken with or without food?

Do I need to use a birth control method while using Capecitaris 500mg Tablet?

How long do I need to take Capecitaris 500mg Tablet?

Does Capecitaris 500mg Tablet make you tired?

What is the most important information that I should know about Capecitaris 500mg Tablet?

What kind of drug is Capecitaris 500mg Tablet?

Do I need to get any tests done while on Capecitaris 500mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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