Author Details
Written By
PhD (Pharmacology), PGDPRA
Reviewed By
Last updated:
18 Feb 2020 | 05:26 PM (IST)
Want to know more?
Read Our Editorial Policy
Have issue with the content?
Report Problem

Calmese 2mg Injection

Prescription Required
Store in a refrigerator (2 - 8°C). Do not freeze.


Calmese 2mg Injection is a prescription medicine used to treat status epilepticus, a medical emergency when a prolonged seizure occurs or continuous seizure occurs within a span of five minutes, even before the person recovers from the previous one.

Calmese 2mg Injection is also used to induce anesthesia before an investigation or a surgical procedure. It relieves anxiety and muscle tension, thus making the person comfortable before the operation or investigation procedure. This medicine is given as an injection under the supervision of a healthcare professional. Calmese 2mg Injection may be given into your vein (intravenously) or into one of your muscles (intramuscularly). The recommended dose depends on your age, weight and why it is being used for you. It is usually used for a short-term only owing to its high habit-forming potential.

Side effects of this medicine include drowsiness, sedation, tiredness, confusion, depression, muscle weakness. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you are pregnant, planning to conceive or breastfeeding before taking this medicine.

Uses of Calmese Injection

  • Status epilepticus

Side effects of Calmese Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Calmese

  • Sedation
  • Dizziness

How to use Calmese Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Calmese Injection works

Calmese 2mg Injection is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Safety Advice

It is unsafe to consume alcohol with Calmese 2mg Injection.
Calmese 2mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Calmese 2mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Calmese 2mg Injection should be used for short periods and sleepiness of the baby should be watched. The withdrawal of Calmese 2mg Injection should be gradual.
Calmese 2mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Calmese 2mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Calmese 2mg Injection may be needed. Please consult your doctor.
However, inform your doctor if you have any underlying kidney disease.
Calmese 2mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Calmese 2mg Injection may be needed. Please consult your doctor.
Use of Calmese 2mg Injection is not recommended in patients with severe liver disease.

What if you forget to take Calmese Injection?

If you miss a dose of Calmese 2mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Calmese 2mg Injection
₹6.06/ml of Injection
Lorazen Injection
Zenith Healthcare Ltd
₹7.45/ml of Injection
23% costlier
Lora 2mg Injection
Orchid Chemicals & Pharmaceuticals Ltd
₹7.8/ml of Injection
29% costlier
Loranza Injection
Arinna Lifescience Pvt Ltd
₹8/ml of Injection
32% costlier
Lopam 2mg Injection
Kivi Labs Ltd
₹8.56/ml of Injection
41% costlier
Lopez 2mg Injection
Intas Pharmaceuticals Ltd
₹8.68/ml of Injection
43% costlier

Quick Tips

  • Calmese 2mg Injection is injected into a vein or muscle by your doctor or healthcare professional.
  • The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid consuming alcohol as it may increase dizziness and drowsiness.
  • Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
  • Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Fact Box

Chemical Class
Benzodiazepines Derivative
Habit Forming

Interaction with Drugs

Taking Calmese with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
Brand(s): Adesera, Adheb, Adfovir
Brand(s): Stozen, Sulpigold, Amisulide
Brand(s): Triptam

Patient Concerns

I have diarrhoea today so please suggest me for it diesies
Dr. Pushkar Mani
loperamide 2mg twice daily for 1 day
Sir i have been prescribed entroquinol 3 times a day for loose motions & after 4 days the condition has not been improved. So can you suggest any better medicine.?
Dr. Pushkar Mani
take loperamid 2mg twice daily for 3 day
Do you have any questions related to Calmese 2mg Injection ?


Q. Is Calmese 2mg Injection an opioid? Is it a habit-forming medicine?

No, Calmese 2mg Injection is not an opioid. It belongs to the benzodiazepine group of medicines and is used for short-term treatment (2-4 weeks) only. It is a habit-forming medicine and can make a person physically and psychologically dependent.

Q. For how long will Calmese 2mg Injection stay in my system?

Calmese 2mg Injection may take around 3 days to get completely removed from the system.

Q. Are there any symptoms that I would experience if I get addicted to Calmese 2mg Injection?

The most important symptom of addiction is that you may feel unpleasant if you do not take Calmese 2mg Injection. Another symptom could be that you may increase the dose on your own to feel its effect.

Q. If I suddenly stop taking Calmese 2mg Injection, will it affect me adversely?

You should reduce the dose of Calmese 2mg Injection gradually before completely stopping it. Suddenly stopping it may lead to withdrawal symptoms which include loss of the sense of reality, feeling detached from life, and unable to feel emotion. Some patients have also experienced numbness or tingling in the arms or legs, tinnitus (ringing sounds in the ears), uncontrolled or overactive movements, twitching, shaking, feeling sick, being sick, stomach upsets or stomach pain, loss of appetite, agitation and abnormally fast heart beats. It can also cause panic attacks, dizziness or feeling faint, memory loss, hallucinations, feeling stiff and unable to move easily, feeling very warm, convulsions (sudden uncontrolled shaking or jerking of the body) and oversensitivity to light, sound and touch.

Q. Does Calmese 2mg Injection cause weight gain?

The effect of Calmese 2mg Injection on weight gain or loss is not known.

Q. Does Calmese 2mg Injection cause depression?

If you have a history of depression then it may increase the risk of developing depression again. Calmese 2mg Injection should not be used alone in depressed patients because it may cause suicidal tendencies in such patients.

Q. My old uncle is taking Calmese 2mg Injection for sleeplessness associated with anxiety. Can it affect his memory?

Though it is rare, but use of Calmese 2mg Injection can cause memory impairment, which may be more apparent in old age patients.

Q. Are there any harmful effects of taking more than the recommended doses of Calmese 2mg Injection?

Taking more than the recommended dose of Calmese 2mg Injection may cause loss of muscle control, low blood pressure, mental confusion, slow breathing and even coma. If you have taken higher than the recommended dose of Calmese 2mg Injection, seek immediate medical help immediately.
Want to share the information?


1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


  1. Stahl SM, editor. Lorazepam. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 367-71.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 819-20.
  3. Lorazepam Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

11/12, Udyog Nagar, S. V. Road, Goregaon (W), Mumbai- 400104.
Country of Origin: India
We do not facilitate sale of this product at present


Orders Delivered
Get the link to download App

All products displayed on 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited


1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant


Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

India's only LegitScript and ISO/IEC 27001 certified online healthcare platform
Know More About 1mgdownArrow
Access medical and health information

1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1000 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.