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30 May 2020 | 06:20 AM (IST)
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Buxoric 80 Tablet


Overview

Introduction

Buxoric 80 Tablet is a medicine used to treat and prevent gout. Gout happens when there is too much uric acid in your body and it forms into crystals which can appear around your joints leading to painful and swollen joints. This medicine helps to keep uric acid levels low.

Buxoric 80 Tablet can be taken with or without food. You should keep taking it as recommended by your doctor even when you are not having a gout attack. If you stop, your symptoms may get worse because of the formation of more crystals in your joints. You can help yourself by making some changes to your diet (eg. avoiding alcohol and non-vegetarian foods) and drinking plenty of fluids.

Some of the common side effects of this medicine are headache, diarrhea, nausea, skin rash and a temporary increase in gout symptoms (rapid onset of severe pain, warmth, and redness in the joint). However, do not stop taking it. Your doctor may advise you some painkillers and additional medicines to help you reduce or prevent these symptoms. Rarely, some people may get a severe allergic reaction (difficulty in breathing, hives, swelling of face and throat, weakness) which may need urgent medical attention. Also, tell your doctor right away if you get any symptoms of liver disease like persistent nausea, dark urine or yellowing of the eyes or skin.

Before taking this medicine, let your doctor know if you have any heart problems, stroke, thyroid problems, or kidney or liver problems. If you are pregnant or breastfeeding, this medicine is best avoided. Check with your doctor. You will need regular blood tests while taking this medicine to check that your liver is working properly.

Uses of Buxoric Tablet

Benefits of Buxoric Tablet

In Gout

Buxoric 80 Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high, crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain, redness, warmth, and swelling. This medicine works by preventing crystals from forming and reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.

Side effects of Buxoric Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Buxoric

  • Diarrhea
  • Headache
  • Increased liver enzymes
  • Nausea
  • Skin rash
  • Gout flares

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Skin rash
    There are many treatments for a wide range of skin problems. Avoid hot showers or baths because hot water can irritate the skin. Make sure to pat dry your skin after a bath or shower. Do not rub or scratch the affected area. Leave the skin exposed to the air as much as possible. Do not use perfumed soaps or deodorants. Water containing chlorine can make most skin problems worse, so avoid swimming. Avoid spicy foods, alcohol, tobacco smoke and caffeine as it may also make itching worse. Avoid excessive sun exposure. Always use sunscreen and protective clothing when outdoors. Moisturizers can be used regularly to soothe and hydrate the affected area. If it does not get better within a week, speak to a pharmacist or doctor.
  • Coping with Gout flares
    You can help ease the pain by resting and raising the affected limb. Keep the joint cool by applying an ice pack. To prevent flare-ups, drink plenty of fluids but limit or avoid alcohol. Coffee and vitamin C are also believed to lower levels of uric acid which causes gout. Cut down on sugary drinks and avoid foods such as red meat, offal and seafood as they can make your gout worse. If your gout gets worse when taking this medicine, talk to your doctor. There may be an alternative.

How to use Buxoric Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Buxoric 80 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Buxoric Tablet works

Buxoric 80 Tablet is a xanthine oxidase inhibitor. It works by decreasing blood uric acid, which is the chemical that causes gout.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Buxoric 80 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Buxoric 80 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Buxoric 80 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Buxoric 80 Tablet may cause side effects which could affect your ability to drive.
Buxoric 80 Tablet may cause dizziness, sleepiness, blurred vision, numbness or tingling sensation. This may affect your driving ability.
Kidney
CAUTION
Buxoric 80 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Buxoric 80 Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Buxoric 80 Tablet in these patients.
Liver
CAUTION
Buxoric 80 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Buxoric 80 Tablet may be needed. Please consult your doctor.
Limited information is available regarding the use of Buxoric 80 Tablet in these patients.

What if you forget to take Buxoric Tablet?

If you miss a dose of Buxoric 80 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Buxoric 80 Tablet
₹16.8/Tablet
Febumac 80 Tablet
Macleods Pharmaceuticals Pvt Ltd
₹16.8/Tablet
same price
Febutaz 80 Tablet
Sun Pharmaceutical Industries Ltd
₹19.3/Tablet
15% costlier
Febuget 80 Tablet
Sun Pharmaceutical Industries Ltd
₹19.3/Tablet
15% costlier
Zurig 80 Tablet
Zydus Cadila
₹20.3/Tablet
21% costlier
₹21.15/Tablet
26% costlier

Quick Tips

  • Your doctor has prescribed Buxoric 80 Tablet to reduce episodes of gout attack.
  • Take it at the same time every day, with or without food.
  • Take plenty of fluids (2-3 litres) daily while on Buxoric 80 Tablet.
  • When you first start taking this medicine, you might have more gout attacks. Do not stop Buxoric 80 Tablet on having an acute attack of gout as that could make an attack worse.
  • Do not consume alcohol while taking this medicine as it may cause your gout to flare up.
  • Stop taking this medicine and inform your doctor straight away if you have symptoms like rash, itchiness, difficulties in breathing, fever or swelling of limbs or face.

Fact Box

Chemical Class
Thiazole Derivative
Habit Forming
No

Patient Concerns

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Iam having gout uric acid ) for past 6-7 years and having gout attack on and off . What should be the ling term cure and suggest some pain killers during an attack My uric acid level was 9.7 on april
Dr. Rohit Chakor
Orthopaedics
You'll have to control on diet. Consult a dietician for advice regarding diet restrictions. Also start febusta 80 once daily. You need to take tablet ultracet during attack
Respected Sir/Mam, I have diagnosed Gout since 2012, now days I am taking goutnil tab. Sr. Uric acid level is 9.8. Though I have taking medicine since long. Moreover I have stiffness in both legs, hence I can't sit down since 2009. Please do the needful and oblige to me.
Vipul Aggarwal
need to be seen clinically tab febuxor 80 mg once a day for 1 month drink plenty of water
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Do you have any questions related to Buxoric 80 Tablet ?

User Feedback


FAQs

Q. What is Buxoric used for?

Buxoric is used to treat gout in adults. It is mainly used in patients who did not respond to the treatment with allopurinol or who are not able to take allopurinol. Gout is a type of arthritis in which uric acid, a naturally occurring substance in the body, builds up in the joints. It causes sudden attacks of redness, swelling, pain and heat in one or more joints.

Q. What are the side effects of Buxoric?

Buxoric may cause common side effects such as abnormal liver test results, diarrhea, headache, rash, nausea, and even an increase in gout symptoms and localized swelling due to retention of fluids in tissues (edema). Whereas, the serious side effects of Buxoric include heart problems, gout flares, liver problems, and severe skin and allergic reactions. Immediately inform your doctor if you experience any serious side effects.

Q. How long should I take Buxoric?

The dose and duration of Buxoric varies from person to person and will be decided by your doctor. It may take several months before Buxoric begins to prevent gout attacks. Do not stop taking Buxoric without the advice of your doctor even if you feel better.

Q. What is the best time to take Buxoric?

Buxoric is advised to be taken once a day. It can be taken at any time of the day, but preferably at the same time each day so that you remember to take it every day. This will help maintain the levels of Buxoric in the body. You can take this medicine with or without food.

Q. Can Buxoric cause kidney damage?

Buxoric may affect kidneys in different ways, though it is quite uncommon. You may experience blood in the urine, frequent urination, kidney stones, abnormal urine tests (increased level of proteins in the urine) and a reduction in the ability of the kidneys to function properly. Rarely, it may cause changes or decrease in urine amount due to inflammation in the kidneys (tubulointerstitial nephritis). Consult your doctor if your kidney functions get further affected.

Q. Can I stop taking Buxoric on my own if I am fine and have no pain or swelling in joints?

No, do not stop taking Buxoric without the advice of your doctor even if you feel better. Discontinuation of medicine may increase the levels of uric acid. It may also worsen your symptoms due to the formation of new crystals of urate in and around your joints and kidneys.

Q. What are the things which I need to know while taking Buxoric?

You should be aware that Buxoric may cause serious heart problems which can be life-threatening in some cases. The symptoms of heart problems include chest pain, shortness of breath or trouble breathing, dizziness, fainting or feeling light-headed, rapid or irregular heartbeat. It may also cause numbness or weakness in one side of your body, slurring of speech and sudden blurry vision, or sudden severe headache. Immediately inform your doctor and seek medical help if you experience any of these symptoms.

Q. Can Buxoric cause any liver problems?

Yes, Buxoric use may cause liver problems. Your doctor may advise you to get regular blood tests done before and during treatment with Buxoric to check how well your liver was working before and while taking this medicine. Inform your doctor if you notice symptoms such as fatigue, pain or tenderness on the right side of the abdomen or loss of appetite for several days or longer. It may also cause changes in the color of urine (dark or tea colored) and may make your skin or the white part of your eyes turn yellow (jaundice).

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 997-98.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 534-35.
  3. Medscape. Febuxostat. [Accessed 02 Apr. 2019] (online) Available from:External Link
  4. Febuxostat. Wooburn Green, Buckinghamshire: A. Menarini Farmaceutica Internazionale SRL; 2008 [revised 29 Oct. 2018]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Febuxostat. Deerfield, Illinois: Takeda Pharmaceuticals America, Inc.; 2009. [Accessed 02 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
A licensed vendor partner from your nearest location will deliver Buxoric 80 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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