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Bosutris 400 Tablet

Bosutinib (400mg)

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Bosutris 400 Tablet is an anti-cancer medicine. It is used in the treatment of certain blood cancer known as chronic myeloid leukemia. This medicine helps to slow down the growth and multiplication of cancer cells, thereby reducing the progress of the disease.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)

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General Information

Contains

Bosutinib (400mg)

Marketer

Mylan Pharmaceuticals Pvt Ltd - A Viatris Company

Storage

Store below 30°C

The content is shown in English

Product introduction

Bosutris 400 Tablet should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how long. You may take it with or without food. Take it regularly and take it at a fixed time each day to help you remember. You should not stop taking the medicine suddenly and continue taking it for as long as the doctor has prescribed.

Common side effects of this medicine include respiratory tract infection, nasopharyngitis, low blood platelets, decreased white blood cell count, anemia, headache, breathlessness, cough, increased liver enzymes, diarrhea, vomiting, nausea, and abdominal pain. If any of these bothers you, let your doctor know. There may be ways of reducing or preventing them. You should also inform the doctor immediately if it causes severe headaches, swelling in one leg, pain on breathing, or changes in vision or hearing.

Before taking Bosutris 400 Tablet, you should let your doctor know if you have any other preexisting medical conditions. You should also inform the doctor about all other medicines that you are taking. Pregnant and breastfeeding women should not take this medicine as it can cause harmful effects to the developing baby.

Uses of Bosutris Tablet

Blood cancer (Chronic myeloid leukaemia)

Benefits of Bosutris Tablet

Blood cancer (Chronic myeloid leukaemia)
Chronic myeloid leukaemia is a type of blood cancer where the bone marrow makes too many abnormal white blood cells. Bosutris 400 Tablet helps control the growth of these cancerous cells and reduces their spread in the body. This helps improve blood counts, manage symptoms like fatigue and weight loss, and slows disease progression, allowing patients to live longer and healthier lives.

Side effects of Bosutris Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bosutris

Abdominal pain
Nausea
Vomiting
Diarrhea
Headache
Cough
Low blood platelets
Anemia (low number of red blood cells)
Nasopharyngitis (inflammation of the throat and nasal passages)
Respiratory tract infection
Decreased white blood cell count (neutrophils)
Breathlessness
Increased liver enzymes

How to use Bosutris Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bosutris 400 Tablet may be taken with or without food.

How Bosutris Tablet works

Bosutris 400 Tablet is a tyrosine kinase inhibitor that is used as an anti-cancer medication. It works by blocking the action of the abnormal protein that promotes the growth and spread of cancer. This helps to stop or slow the spread of cancer cells.

Quick tips

Bosutris 400 Tablet is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bosutris 400 Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Bosutris 400 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CAUTION

Bosutris 400 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Bosutris 400 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Bosutris 400 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

UNSAFE

Bosutris 400 Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Bosutris with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Ondansetron (Oral Route)

Do not consume Ondansetron with Bosutinib.

Life-threatening

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Bosutinib.

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Bosutinib.

Life-threatening

Tetrabenazine (Oral Route)

Do not consume Tetrabenazine with Bosutinib.

Life-threatening

Ondansetron (Injection Route)

Do not consume Ondansetron with Bosutinib.

Frequently asked questions

When should I call my doctor right away?

Get medical help right away if you have muscle cramping, muscle weakness, confusion, visual loss or disturbances, blindness, seizures, headaches, shortness of breath, swelling of your feet or changes in your heartbeat, high blood pressure, tiredness, fainting, coughing and breathing difficulties or tightness in the chest.

How will you know that Bosutris 400 Tablet is working?

Keep taking this medicine exactly as directed until your doctor tells you to stop. Regular scans will reveal whether your tumor is responding to the treatment. Your doctor will determine when those scans should be scheduled.

What precautions should I take to reduce the chances of getting infected during treatment with Bosutris 400 Tablet?

Since Bosutris 400 Tablet lowers the number of white blood cells and platelets in your blood, it puts you at a risk of getting an infection or bleeding. In order to prevent, avoid people who have infections. Check with your doctor immediately if you think you may be getting an infection, or if you get a fever, chills, cough; be careful not to cut yourself when you are using sharp objects such as a razor or nail cutters, and use a toothbrush with soft bristles to prevent bleeding from gums.

Can Bosutris 400 Tablet be used during pregnancy?

No, this medicine should not be used during pregnancy as it can harm your unborn baby. Avoid getting pregnant and use an effective method of birth control during your treatment and for at least 3 months after the last dose of Bosutris 400 Tablet.

Can Bosutris 400 Tablet affect my lungs? What should I do?

Yes, this medicine might cause potentially fatal problems in your lung. If you feel severe shortness of breath, confusion, dry cough, dizziness, or extreme tiredness, talk to your doctor right away.

Does Bosutris 400 Tablet cause hair loss?

Yes, while taking this medicine, your hair may become brittle and break. You may also experience patchy hair loss or thinning. These conditions tend to resolve once treatment is stopped. Be gentle when brushing and washing hair to manage hair loss.

Are there any precautions for tingling sensation and numbness in my arms and legs?

This medicine causes tingling, numbness, pain, or burning sensation in your arms or legs. Be careful when moving around, as the numbness may make it harder to walk, feel your hands or feet, or increase your risk of falls. Talk to your doctor if you feel these symptoms. You may need to change your dose or schedule.

I have noticed some changes in my skin after taking Bosutris 400 Tablet? What should I do?

Use a moisturizer to get relief from rashes, dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen with (SPF more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water bath and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

How to relieve constipation during the treatment?

To relieve constipation, include fiber in your diet (fruits and vegetables), drink 8-10 glasses of fluids a day, and keep active. A stool softener (with a doctor's prescription) once or twice a day may prevent constipation. If you do not have a bowel movement for 2-3 days, consult your doctor.

I am experiencing nausea and extreme tiredness. Is this due to Bosutris 400 Tablet?

Nausea and fatigue or tiredness are some of the common side-effects of this medicine. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid food that is salty, spicy, fried, or fatty. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

I am noticing a change in my taste. How shall I improve my taste?

You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You can also add extra flavor or seasonings to your food.

Fact Box

Chemical Class

4- aminoquinolines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

References

Bosutinib [FDA Label]. New York, NY: Pfizer Labs; 2017. [Accessed 18 Dec. 2020] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mylan Pharmaceuticals Pvt Ltd - A Viatris Company
Address: Mylan Pharmaceuticals Private Limited , Commercial Operations , Prestige Tech Park,Platina-3, 7th to 12th floor, Prestige Tech Park, Kadubesanahalli, Bangalore -560103

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Bosutris 400 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Bosutris 400 Tablet

Payment

Free Return

Expiry after

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Bosutris Tablet

Benefits of Bosutris Tablet

Side effects of Bosutris Tablet

How to use Bosutris Tablet

How Bosutris Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Ondansetron (Oral Route)

Hydroxyzine (Oral Route)

Domperidone (Oral Route)

Tetrabenazine (Oral Route)

Ondansetron (Injection Route)

Frequently asked questions

When should I call my doctor right away?

How will you know that Bosutris 400 Tablet is working?

What precautions should I take to reduce the chances of getting infected during treatment with Bosutris 400 Tablet?

Can Bosutris 400 Tablet be used during pregnancy?

Can Bosutris 400 Tablet affect my lungs? What should I do?

Does Bosutris 400 Tablet cause hair loss?

Are there any precautions for tingling sensation and numbness in my arms and legs?

I have noticed some changes in my skin after taking Bosutris 400 Tablet? What should I do?

How to relieve constipation during the treatment?

I am experiencing nausea and extreme tiredness. Is this due to Bosutris 400 Tablet?

I am noticing a change in my taste. How shall I improve my taste?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Bcr-Abl Gene Translocation (Qualitative)

Bcr-Abl Gene Translocation (Quantitative)

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests