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Bonspark Injection

Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Bonspark Injection is a man-made version of the parathyroid hormone used to treat men and postmenopausal women who have severe osteoporosis with a high risk of fractures. It works by stimulating new bone formation, which improves bone density and decreases the risk of spinal fractures.
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1/2
3 ml Injection
 
 
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General Information

Contains

Teriparatide (750mcg)

Marketer

Integrace Pvt Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Bonspark Injection image
Bonspark Injection image

Product introduction

Bonspark Injection should be injected under the skin or given by a healthcare professional. You should use it regularly and at the same time each day to get the maximum benefit from it. Usually, it is recommended to take it for a maximum period of 2 years. However, follow the doctor’s advice and complete the course even if you feel better.


Some common side effects of this medicine include joint pain, injection site reactions (such as pain, swelling, and redness), and nausea. Consult with your doctor if any of these bother you or do not go away.


Before taking this medicine, let your doctor know if you have kidney stones or any other kidney problems, as it can cause an increase in the amount of calcium in blood or urine. Pregnant and breastfeeding mothers should also consult with their doctors before taking this medicine. Your doctor may advise a bone scan to monitor the progress of your treatment.

Uses of Bonspark Injection

Benefits of Bonspark Injection

Osteoporosis
Bonspark Injection is a valuable treatment for osteoporosis, especially in individuals at high risk of fractures. It stimulates new bone formation, increases bone mineral density, and improves bone strength. This significantly reduces the risk of fractures, particularly in the spine and hip. Strengthening the bones helps individuals maintain mobility, reduce pain, and preserve independence, ultimately improving their overall quality of life.

Side effects of Bonspark Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Bonspark
  • Joint pain
  • Injection site reactions (pain, swelling, redness)
  • Nausea

How to use Bonspark Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bonspark Injection works

Bonspark Injection is a synthetic form of a natural human hormone called parathyroid hormone (PTH). It works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.

Quick tips

  • Bonspark Injection should be injected every day under the skin (subcutaneous injection) of the thigh or abdomen.
  • You may have low blood pressure and dizziness during the initial few days.
  • If you feel dizzy (light-headed) after the injection, sit or lie down until you feel better.
  • Tell your doctor immediately if you experience nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs of high calcium levels in your blood.
  • Tell your doctor if you are pregnant, breastfeeding, or planning to become pregnant.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Bonspark Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Bonspark Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Bonspark Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Bonspark Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Bonspark Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Bonspark Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Bonspark Injection in patients with liver disease.

Interaction with drugs

Taking Bonspark with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Etidronate (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Etidronate may reduce the efficacy of Teriparatide.
Moderate

Pamidronate (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Pamidronate may reduce the efficacy of Teriparatide.
Moderate

Risedronate (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Risedronate may reduce the efficacy of Teriparatide.

Frequently asked questions

No, Bonspark Injection is not a steroid. However, this medicine may be used to treat osteoporosis caused by long-term use of steroids. Generally, this medicine is used to treat osteoporosis in women of the postmenopausal age group and in men who have an increased risk of fracture.
Bonspark Injection should not be taken for a course longer than 2 years. However, your doctor may prescribe Bonspark Injection for more than 2 years if you remain at or have returned to having a high risk for fracture.
Always keep this medicine stored in a refrigerator at a temperature of about 2°C to 8°C. Be cautious; the temperature should not decrease further, as freezing may cause the medicine to get damaged and can lead to loss of activity. Therefore, avoid placing the Bonspark Injection pens close to the ice compartment of the refrigerator. If properly stored, this medication can be used up to 28 days after the first injection. If the pen is not empty within 28 days, please discard it safely.
The doctor will decide whether the medicine is required for a patient or not. There are a few conditions in which the use of Bonspark Injection should be avoided, such as in patients with kidney impairment, Paget’s disease, any type of bone cancer, or unexplained high levels of serum calcium. It should also be avoided by children, young adults (who are still in the growing age), and pregnant or lactating females. Hence, before starting the medication, inform the doctor about any medical conditions and the medication you are taking. This will help the doctor design a proper therapy for you.

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

HORMONES

Action Class

Parathyroid Hormone (PTH) Analogues

Related lab tests

References

  1. Bikle DD. Agents That Affects Bone Mineral Homoestasis. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 766.
  2. Friedman PA. Agents Affecting Mineral Ion Homeostasis and Bone Turnover. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1300
  3. Teriparatide. Indianapolis, Indiana: Lilly France; 2008. [Accessed 02 Apr. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
  5. Teriparatide injection [Prescribing Information]. Indianapolis, IN: Lilly USA, LLC; 2024. [Accessed 01 Apr. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Integrace Pvt Ltd
Address: Rocklines House, Ground Floor 9/2, Museum Road, Bangalore KA 560001 IN

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Bonspark Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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