Bonrin-PTH PFS Injection

Recombinant Human parathyroid hormone (250mcg/ml)

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required

Cold stored

Stored between 2-8°C

Bonrin-PTH PFS Injection is a medicine used in the treatment of postmenopausal osteoporosis. It is used along with other calcium supplements and vitamin D to restore calcium levels in the body.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 15 Jul 2026 | 01:03 AM (IST)

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Gurgaon

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General Information

Contains

Recombinant Human parathyroid hormone (250mcg/ml)

Marketer

Bio-Origin Pharma Pvt.Ltd.

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Bonrin-PTH PFS Injection is given by a healthcare professional and should not be self-administered. You should use it regularly and at the same time each day to get the maximum benefit from it. Continue using it as recommended by your doctor and complete the dose even if you feel better. If you stop, your symptoms may get worse.

Some common side effects of this medicine include paresthesia, hypocalcemia, headache, hypercalcemia, nausea, hypoesthesia, diarrhea, vomiting, arthralgia, hypercalciuria, and pain in extremity. Talk to your doctor if any of these side effects do not go away with time or get worse. Your doctor may help with ways to reduce or prevent these symptoms.

To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys, or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine.

Uses of Bonrin-PTH Injection

Post menopausal osteoporosis

Benefits of Bonrin-PTH Injection

Post menopausal osteoporosis
Osteoporosis is a common condition that weakens bones, making them fragile and more likely to break. It often occurs in women after menopause. This condition can be treated with bone-strengthening medicines. Bonrin-PTH PFS Injection slows down the rate at which bone is broken down in your body and prevents fractures. This maintains bone density and reduces your risk of breaking a bone. The injection is given by a doctor or nurse and should not be self-administered.

Side effects of Bonrin-PTH Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bonrin-PTH

Decreased calcium level in blood
Headache
Increased calcium level in blood
Nausea
Hypoesthesia (decreased sensitivity to stimuli)
Diarrhea
Vomiting
Joint pain
Increased calcium in urine
Pain in extremity
Paresthesia (tingling or pricking sensation)

How to use Bonrin-PTH Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bonrin-PTH Injection works

Bonrin-PTH PFS Injection helps to regulate and maintain the balance of calcium and phosphorus in the human body. Bonrin-PTH PFS Injection works by causing the body to absorb and retain more calcium into the blood.

Quick tips

Bonrin-PTH PFS Injection may increase your calcium level, consult your doctor and get your calcium level monitored at regular intervals.
If you take antacids (medicines to relieve heartburn) or medicines containing calcium, you should take them at least 2 hours after taking Bonrin-PTH PFS Injection to avoid interference.
Inform your doctor immediately if you experience any allergic reactions (rash, swelling and difficulty breathing) after taking Bonrin-PTH PFS Injection.
Let your doctor know if you have or have had a blood clot, heart disease, kidney disease, high blood pressure, or had surgery on the arteries of your legs.
Bonrin-PTH PFS Injection may increase your calcium level, consult your doctor and get your calcium level monitored at regular intervals.
If you take antacids (medicines to relieve heartburn) or medicines containing calcium, you should take them at least 2 hours after taking Bonrin-PTH PFS Injection to avoid interference.
Inform your doctor immediately if you experience any allergic reactions (rash, swelling and difficulty breathing) after taking Bonrin-PTH PFS Injection.
Let your doctor know if you have or have had a blood clot, heart disease, kidney disease, high blood pressure, or had surgery on the arteries of your legs.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bonrin-PTH PFS Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Bonrin-PTH PFS Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Bonrin-PTH PFS Injection during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Bonrin-PTH PFS Injection does not usually affect your ability to drive.

Kidney

CAUTION

Bonrin-PTH PFS Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Bonrin-PTH PFS Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Bonrin-PTH with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Etidronate (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Etidronate may reduce the efficacy of Recombinant Human parathyroid hormone.

Moderate

Digoxin (Oral Route)

watch out for symptoms of Digoxin side effects such as impaired vision, skin rash, nausea, vomiting, diarrhea or dizziness and consult your doctor if you experience them. They may monitor your calcium levels and adjust the doses as per the observations. Digoxin may increase the rate of release of Recombinant Human parathyroid hormone in the blood.

Moderate

Digoxin (Injection Route)

Moderate

Pamidronate (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Pamidronate may reduce the efficacy of Recombinant Human parathyroid hormone.

Moderate

Risedronate (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Risedronate may reduce the efficacy of Recombinant Human parathyroid hormone.

Frequently asked questions

How is Bonrin-PTH PFS Injection given?

Bonrin-PTH PFS Injection will be given to you by a doctor in a hospital or clinic as an injection under your skin (subcutaneous injection).

What is post-menopausal osteoporosis?

Osteoporosis is a common condition that weakens bones, making them fragile and thus putting one at a high risk of fractures. Women have a high risk of developing osteoporosis post menopause due to a decrease in the level of hormones.

How is Bonrin-PTH PFS Injection used to prevent post-menopausal osteoporosis?

Bonrin-PTH PFS Injection works by increasing the number and activity of bone-forming cells (osteoblasts). This strengthens the bones and minimizes the risk of fractures.

Can Bonrin-PTH PFS Injection cause kidney stones?

Bonrin-PTH PFS Injection can cause kidney stones due to excess calcium deposition when used for a long period. Please consult your doctor before taking it as a daily supplement if you have any kidney problems or a history of kidney stones.

Do I need to have any blood tests before I begin taking Bonrin-PTH PFS Injection?

Yes. Before you can begin the treatment with Bonrin-PTH PFS Injection, you need to have a blood test done to check the levels of calcium and vitamin D in your blood.

Fact Box

Chemical Class

Peptides

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Parathyroid Hormone (PTH) Analogues

Related lab tests

Calcium

References

Eremkina AK, Mokrysheva NG, Kovaleva EV, et al. Rekombinantnyĭ paratireoidnyĭ gormon cheloveka v terapii gipoparatireoza [Recombinant human parathyroid hormone in the therapy of hypoparathyroidism]. Ter Arkh. 2017;89(10):80-86. Russian. [Accessed 05 Jan. 2026]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bio-Origin Pharma Pvt.Ltd.
Address: B-112,FIRST FLOOR,DDA SHEDS OKHLA INDUSTRIAL ESTATE PHASE-1,NEW DELHI-110020,

Vendor Details

Country of origin: India

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Bonrin-PTH PFS Injection

Bonrin-PTH PFS Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Bonrin-PTH Injection

Benefits of Bonrin-PTH Injection

Side effects of Bonrin-PTH Injection

How to use Bonrin-PTH Injection

How Bonrin-PTH Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Etidronate (Oral Route)

Digoxin (Oral Route)

Digoxin (Injection Route)

Pamidronate (Injection Route)

Risedronate (Oral Route)

Frequently asked questions

How is Bonrin-PTH PFS Injection given?

What is post-menopausal osteoporosis?

How is Bonrin-PTH PFS Injection used to prevent post-menopausal osteoporosis?

Can Bonrin-PTH PFS Injection cause kidney stones?

Do I need to have any blood tests before I begin taking Bonrin-PTH PFS Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Calcium

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests