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Bisonate 500mg Tablet

Prescription Required

Product introduction

Bisonate 500mg Tablet is an antacid used in the treatment of indigestion, metabolic acidosis and used as an alkalinizing agent. It acts as a buffer that helps neutralize excess acid and restore a healthier pH level in the body.

Bisonate 500mg Tablet relieves irritation by producing carbon dioxide which neutralizes the acid present in the stomach. It also increases the pH of blood and urine, thereby correcting acid indigestion, heartburn. Additionally, it helps in the removal of toxic substances from the body in certain types of poisoning.

Bisonate 500mg Tablet may be taken with or without food in a dose and duration as advised by the doctor. Excessive intake may cause electrolyte imbalance leading to unwanted side effects. Keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen.

Common side effects of this medicine include high sodium levels, cerebral edema, alkalosis, and hypokalemia. Let your doctor know if any of these side effects persist or get worse. They may be able to help by adjusting the dosage or by prescribing you an alternate medicine.

It is important to consult a doctor before taking Bisonate 500mg Tablet if you are suffering from stomach and kidney disease. Let your doctor also know about all other medications you are taking as some may affect, or be affected by this medicine. Pregnant or breastfeeding women should also consult their doctor before taking this medicine.

Uses of Bisonate Tablet

Benefits of Bisonate Tablet

In Treatment of Indigestion

Indigestion is a feeling of discomfort or a burning sensation in the upper part of your stomach. It also causes stomach pain and a feeling of fullness. Bisonate 500mg Tablet treats indigestion and thus gives relief from its symptoms by reducing the amount of acid in the stomach. Bisonate 500mg Tablet also gives relief from excess gas by breaking trapped gas and allows its easy passage. Take Bisonate 500mg Tablet as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Avoid eating within 3-4 hours of going to bed.

In Treatment of Alkalinizing agent

Alkalinizing agents are medicines used to manage disorders associated with low pH. Bisonate 500mg Tablet is used to treat metabolic acidosis (a condition where there is too much acid in the body) due to kidney failure. It helps restore the lost electrolyte balance and raises the pH of the urine and blood. This prevents complications that may arise due to metabolic acidosis such as osteoporosis, kidney damage, weakening of muscles, fatigue etc. It is given as an injection by a doctor or nurse and should not be self-administered. Follow your doctor’s instructions carefully to get the most benefit.

In Treatment of Metabolic acidosis

Metabolic acidosis occurs when the body accumulates too much acid or loses too much base, leading to a disrupted pH level. Bisonate 500mg Tablet acts as a buffer that helps neutralize excess acid and restore a healthier pH level. This prevents further complications related to the acidosis, such as organ dysfunction and electrolyte imbalances. This way it supports the proper functioning of various bodily systems and promotes overall health.

Side effects of Bisonate Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bisonate

  • Increased sodium level in blood
  • Brain swelling
  • Alkalosis
  • Decreased potassium level in blood

How to use Bisonate Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisonate 500mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Bisonate Tablet works

Bisonate 500mg Tablet works primarily by providing a source of bicarbonate ions to the body. Bisonate 500mg Tablet neutralizes the acidity in stomach, providing relief from the discomfort of acid reflux or heartburn. It can help temporarily increase the pH of the blood, making it less acidic. This property can be useful in certain medical situations, such as metabolic acidosis, where the body becomes too acidic due to conditions like kidney dysfunction or severe dehydration. Bisonate 500mg Tablet may also help in cases where the urine needs to be less acidic, such as when trying to promote the excretion of certain drugs or when managing certain urinary tract conditions.

Safety advice

It is unsafe to consume alcohol with Bisonate 500mg Tablet.
Bisonate 500mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
Information regarding the use of Bisonate 500mg Tablet during breastfeeding is not available. Please consult your doctor.
Bisonate 500mg Tablet does not usually affect your ability to drive.
Bisonate 500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Bisonate 500mg Tablet may be needed. Please consult your doctor.
Bisonate 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Bisonate 500mg Tablet may be needed. Please consult your doctor.

What if you forget to take Bisonate Tablet?

If you miss a dose of Bisonate 500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Bisonate 500mg Tablet
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Fact Box

Chemical Class
Organic Carbonic Acids
Habit Forming
Therapeutic Class
Action Class

Interaction with drugs

Taking Bisonate with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec
Brand(s): Aspirin, Actisprin, Asicom
Brand(s): Adesera, Adheb, Adfovir
Brand(s): Alendrate

Patient concerns

Kindly tell me the medicines in tablet or capsule Form to get rid of chronic indigestion and to increase appetite.
Dr. Rajesh Chhabra
Please elaborate chronic indigestion
Why tranexamic acid is prescribed in skin specialists prescription
Dr. Dharamvir Singh
It's a skin whitening agent used for pigmentation

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


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  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Sodium Bicarbonate [Product Information]. Ahmedabad, Gujarat: La Renon Healthcare Provate Limited. [Accessed 01 Aug. 2023]. (online) Available from:External Link
  5. Sodium Bicarbonate [Product Label]. Mehatpur, India: Stanford Laboratories Private Limited. [Accessed 06 Aug. 2023]. (online) Available from:External Link

Marketer details

Name: Cmg Biotech Pvt Ltd
Address: 410, plot no. 4, dda building, swasthya vihar, delhi, 110092
Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.

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