Atef 250mg Tablet

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 19 Jan 2026 | 04:30 PM (IST)

Atef 250mg Tablet belongs to a group of medicines called antifungals It is used to treat a wide range of fungal infections of the skin and nails, including ringworm. It works by killing the fungi that cause the infection.

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Atef 250mg Tablet

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Terbinafine (250mg)

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General Information

Contains

Terbinafine (250mg)

Marketer

Atopic Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Atef 250mg Tablet can be taken with or without food. You should take it regularly as prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

This medicine's most common side effects include rash, headache, nausea, and abnormal liver enzyme. These are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it. Your doctor will monitor your liver function regularly during treatment.

Uses of Atef Tablet

Fungal infections

Benefits of Atef Tablet

Fungal infections
Atef 250mg Tablet is an antifungal medicine. It works by killing and stopping the growth of fungus causing the infection. The dose and duration of treatment will depend on what you are being treated for. Make sure you complete the full dose your doctor has prescribed. This will ensure that the infection is completely cured and prevent it from returning.

Side effects of Atef Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Atef

Headache
Taste change
Nausea
Abdominal pain
Flatulence
Itching
Diarrhea
Rash
Indigestion
Abnormal liver enzyme

How to use Atef Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Atef 250mg Tablet may be taken with or without food.
Avoid Atef 250mg Tablet with caffeine and chocolate as well as food containing caffeine and chocolate such as tea leaves, cocoa beans.

How Atef Tablet works

Atef 250mg Tablet is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection.

All substitutes for Atef 250mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Atef 250mg Tablet helps treat fungal infections of the skin and nails.
Do not skip any doses and finish the full course of treatment even if you feel better.
Treatment may be needed for 2 to 6 weeks for skin infections and 6 weeks to 6 months for nail infections.
Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Atef 250mg Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Atef 250mg Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Atef 250mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Atef 250mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Atef 250mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

UNSAFE

Atef 250mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Interaction with drugs

Taking Atef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tamoxifen (Oral Route)

Do not consume Tamoxifen with Terbinafine.

Severe

Doxorubicin (Plain) (Injection Route)

Your doctor may monitor ECG (electrocardiogram).

Severe

Doxorubicin (Liposomal) (Injection Route)

Your doctor may monitor ECG (electrocardiogram).

Moderate

Metoprolol Succinate (Oral Route)

Careful consideration is advised when taking Metoprolol Succinate with Terbinafine. If concurrent use is essential, please consult your doctor. Terbinafine may raise blood levels of Metoprolol Succinate.

Moderate

Carbamazepine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Frequently asked questions

Can Atef 250mg Tablet be safe for use in patients with liver cirrhosis?

Oral intake of Atef 250mg Tablet is not recommended in patients with chronic or active liver disease. Your doctor may prescribe a liver function test to check whether the liver is functioning effectively or not. This is done because the medicine gets metabolized by liver enzymes and any inefficiency in liver function can lead to increased levels of the medication in the blood, resulting in increased side effects and toxicity. Therefore, it is important to inform your doctor if you have any liver disease or cirrhosis. Also, inform your doctor about the medicines you may be taking as taking Atef 250mg Tablet with another medicine can lead to liver toxicity and Atef 250mg Tablet by acting on the liver enzymes can change the levels of other drugs. Your doctor may suggest periodic monitoring (after 4-6 weeks of treatment) of liver function test and make dose adjustments accordingly.

Does Atef 250mg Tablet cause any skin reactions?

Yes, sensitive individuals may develop skin reactions while using Atef 250mg Tablet. There are rare reports of people developing serious skin/hypersensitivity reactions like Stevens-Johnson syndrome, toxic epidermal necrolysis, and other severe skin reactions with Atef 250mg Tablet. Therefore, do not take this medication without consulting your physician. And, in case you encounter any type of skin reaction or rashes, stop the medication immediately and report to the doctor.

Is Atef 250mg Tablet effective?

Atef 250mg Tablet is effective as an anti fungal medicine if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop taking this medicine too early, the fungus may continue to grow and the infection may return or worsen.

How long do I need to take Atef 250mg Tablet?

The usual duration of treatment for Tinea pedis (fungal infection in the foot), Tinea corporis (ringworms), and Tinea cruris (fungal infection in the groin) is about 2 to 4 weeks. The duration may sometimes be extended to 6 weeks. For fungal infections of nails, the duration of treatment usually varies from 6 to 12 weeks. For fingernail fungal infections it may take 6 weeks whereas toenail fungal infection may take about 12 weeks. However, the exact duration of the therapy is decided by the doctor depending upon the type of infection, the site of infection, and the patient’s response to the therapy.

Can I drink tea or coffee while taking Atef 250mg Tablet?

Caffeinated drinks like tea and coffee should be taken with caution while being on treatment with Atef 250mg Tablet. Atef 250mg Tablet decreases the rate of metabolism of caffeine by 19% which is an important constituent of coffee, thereby increasing the levels of caffeine in the blood. These increased levels of caffeine may lead to side effects such as jitteriness, headache, increased heartbeat, and restlessness.

Fact Box

Chemical Class

Naphthalene derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Fungal Ergosterol Synthesis Inhibitor

Related lab tests

Culture Fungus

References

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1586, 1588.
Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1051, 1053.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1329.
Terbinafine hydrochloride [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2012. [Accessed 28 Mar. 2023] (online) Available from:
Terbinafine hydrochloride [Prescribing Information]. Hyderabad, Tamil Nadu: NorthStar Rx LLC; 2024. [Accessed 19 Jan. 2026] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Atopic Laboratories
Address: Building Zone-B No-6, Aagaman, Vallabhavadi,Near Westend Hotel, Gujarat Collage, Ellisbridge, Ahmedabad – 380006., Gujarat,INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Atef 250mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Atef Tablet

Benefits of Atef Tablet

Side effects of Atef Tablet

How to use Atef Tablet

How Atef Tablet works

All substitutes for Atef 250mg Tablet

Terbifex 250 Tablet

Texifen 250mg Tablet

Terbinaforce Tablet

SeBIFin Tablet

Gris ODT 250mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tamoxifen (Oral Route)

Doxorubicin (Plain) (Injection Route)

Doxorubicin (Liposomal) (Injection Route)

Metoprolol Succinate (Oral Route)

Carbamazepine (Oral Route)

Frequently asked questions

Can Atef 250mg Tablet be safe for use in patients with liver cirrhosis?

Does Atef 250mg Tablet cause any skin reactions?

Is Atef 250mg Tablet effective?

How long do I need to take Atef 250mg Tablet?

Can I drink tea or coffee while taking Atef 250mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Culture Fungus

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests