Asginase 5000IU Injection

Prescription Required
SALT COMPOSITION
Storage
Store in a refrigerator (2 - 8°C). Do not freeze.

Introduction

Asginase 5000IU Injection is used in the treatment of some kinds of cancer of white blood cells (leukemia). It may also be used to treat other types of cancer as determined by your doctor. It may be used on its own, or sometimes given together with certain other medicines as part of combination chemotherapy.

Asginase 5000IU Injection is given as an injection by the doctor, but try to have it the same time each day to make sure it has the best effect. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effect of this medicine includes breathlessness, rash, vomiting, angioedema (swelling of deeper layers of skin), and nausea. It might cause increased blood sugar levels, hence regular blood tests are required to monitor your blood sugar levels, response to the therapy, and any side effects. It is advised that you drink extra fluids so that you pass more urine. This will help prevent bladder and kidney problems and keep your kidneys working well.

This medicine may lower your body's resistance and increase susceptibility to infections. Infections can sometimes be life-threatening.  It is important to use effective contraception to avoid getting pregnant or fathering a child during treatment. Before taking this medicine, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Asginase Injection

  • Blood cancer (Acute lymphocytic leukemia)

Benefits of Asginase Injection

In Blood cancer (Acute lymphocytic leukemia)

Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Asginase 5000IU Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Asginase Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Asginase

  • Breathlessness
  • Rash
  • Vomiting
  • Angioedema (swelling of deeper layers of skin)
  • Edema (swelling)
  • Nausea
  • Fatigue
  • Increased liver enzymes
  • Diarrhea
  • Decreased blood pressure
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Low albumin level in blood
  • Increased glucose level in blood
  • Hives

How to use Asginase Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Asginase Injection works

Asparaginase belongs to class of medications called antineoplastic agents. Asparaginase is an enzyme that interferes with natural processes necessary for cancer cell growth, thereby killing or stopping the growth of cancer cells.
 
.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Asginase 5000IU Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Asginase 5000IU Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Asginase 5000IU Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
SAFE
Asginase 5000IU Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Asginase 5000IU Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Asginase 5000IU Injection may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Asginase 5000IU Injection in patients with liver disease. Please consult your doctor.
However, regular monitoring of liver function tests is advised while you are taking this medicine.

Alternate brands

For informational purposes only. Consult a doctor before taking any medicines.
Asginase 5000IU Injection
₹1053.09/Injection
Celginase 5000IU Injection
Celon Laboratories Ltd
₹975/injection
7% cheaper
L Aspinase 5000IU Injection
RPG Life Sciences Ltd
₹978.2/injection
7% cheaper
Onconase 5000IU Injection
United Biotech Pvt Ltd
₹982.31/injection
7% cheaper
Oncoginase 5000IU Injection
Chandra Bhagat Pharma Pvt Ltd
₹987/injection
6% cheaper
L-Aspase 5000IU Injection
Miracalus Pharma Pvt Ltd
₹1000/injection
5% cheaper

Quick tips

  • Asginase 5000IU Injection is given as an injection into the veins, muscles or under the skin by the healthcare provider.
  • It is advisable to drink plenty of fluids and stay hydrated while taking this medication.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • You may need to have blood tests to monitor your blood cells,  liver function and kidney function during treatment.
  • It can cause an increase in blood sugar levels. Hence, monitor your blood sugar level regularly.
     

Fact Box

Chemical Class
Enzyme
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others

Patient concerns

arrow
I want to know about Acute Lymphoblastic Leukemia CNS Relapse protocol followed by standard doctors.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
What you want know
Features suggestive of acute myeloid leukemia Is this disease is curable if no than how much time did the patient have with & without treatment
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Less chances of cureHowever treatment is possible
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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1720-21.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 956.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 88.
  4. Asparaginase. Wedel, Germany: medac GmbH; 2016 [revised Jun. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Drugs.com. Asparaginase erwinia chrysanthemi Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Expires on or after: November, 2021

A licensed vendor partner from your nearest location will deliver Asginase 5000IU Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
789.821053.09Get 25% OFF
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1 Injection in 1 vial
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