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Aprepep 125mg Capsule

Aprepitant (125mg)
Genuine
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required
Aprepep 125mg Capsule is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 02 Aug 2026 | 01:04 AM (IST)
₹982 MRP ₹1113.7512% off 
Gurgaon
 
 
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General Information

Contains

Aprepitant (125mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C
The content is shown in English
Aprepep 125mg Capsule image
Aprepep 125mg Capsule image

Product introduction

Aprepep 125mg Capsule is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Aprepep Capsule

  • Nausea and vomiting due to chemotherapy

Benefits of Aprepep Capsule

Nausea and vomiting due to chemotherapy
Aprepep 125mg Capsule is used to prevent nausea and vomiting caused by chemotherapy. It helps improve comfort during cancer treatment by blocking signals in the brain that trigger these symptoms, allowing patients to better tolerate their therapy.

Side effects of Aprepep Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Aprepep
  • Headache
  • Diarrhea
  • Dizziness
  • Hiccup
  • Loss of appetite
  • Fatigue
  • Constipation

How to use Aprepep Capsule

Take this medicine in the dose and duration as advised by your doctor. Aprepep 125mg Capsule may be taken with or without food.

How Aprepep Capsule works

Aprepep 125mg Capsule is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

Quick tips

  • Aprepep 125mg Capsule helps prevent nausea and vomiting caused by certain chemotherapy medicines.
  • It will not help if you already have nausea and vomiting.
  • Do not use it continuously for a long time.
  • It is recommended to take Aprepep 125mg Capsule 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
  • It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Aprepep 125mg Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Aprepep 125mg Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Aprepep 125mg Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Aprepep 125mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Aprepep 125mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Aprepep 125mg Capsule should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking Aprepep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Pimozide (Oral Route)

Do not consume Aprepitant with Pimozide.
Life-threatening

Primidone (Oral Route)

Do not consume Aprepitant with Primidone. Primidone may reduce blood levels of Aprepitant.
Severe

Ranolazine (Oral Route)

Watch out for symptoms of Aprepitant side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may adjust the dose of Aprepitant accordingly. Aprepitant may raise blood levels of Ranolazine.
Severe

Carbamazepine (Oral Route)

Do not consume Aprepitant with Carbamazepine. Carbamazepine may reduce blood levels of Aprepitant.
Severe

Phenobarbitone (Oral Route)

Do not consume Aprepitant with Phenobarbitone. Phenobarbitone may reduce blood levels of Aprepitant.

Frequently asked questions

Aprepep 125mg Capsule is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery
Aprepep 125mg Capsule is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

Fact Box

Chemical Class

Phenylmorpholines

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Neurokinin-1 (NK1) Receptor Antagonists

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
  2. Aprepitant. [Accessed 28 Mar. 2019] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

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