Aprepep 125mg Capsule is a prescription medicine used to prevent nausea and vomiting caused by chemotherapy. It is also used in the prevention of postoperative nausea and vomiting in adults.

Aprepep 125mg Capsule is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, hiccups, loss of appetite, fatigue, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is beneficial to drink plenty of fluids while taking this medicine as it may help to prevent dehydration. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning a pregnancy, or breastfeeding. You should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Aprepep Capsule

Nausea and vomiting due to chemotherapy

Side effects of Aprepep Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aprepep

Headache
Dizziness
Hiccup
Loss of appetite
Fatigue
Constipation
Diarrhea

How to use Aprepep Capsule

Take this medicine in the dose and duration as advised by your doctor. Aprepep 125mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Aprepep Capsule works

Aprepep 125mg Capsule is an antiemetic medication. It works by blocking the action of a chemical messenger (neurokinin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Aprepep 125mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Aprepep 125mg Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Aprepep 125mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Aprepep 125mg Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

SAFE IF PRESCRIBED

Aprepep 125mg Capsule is safe to use in patients with kidney disease. No dose adjustment of Aprepep 125mg Capsule is recommended.

Liver

SAFE IF PRESCRIBED

Aprepep 125mg Capsule is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aprepep 125mg Capsule may not be needed in these patients. Please consult your doctor.

What if you forget to take Aprepep Capsule?

If you miss a dose of Aprepep 125mg Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Aprepep 125mg Capsule helps prevent nausea and vomiting caused by certain chemotherapy medicines.
It will not help if you already have nausea and vomiting.
Do not use it continuously for a long time.
It is recommended to take Aprepep 125mg Capsule 1 hour before chemotherapy treatment (Day 1) and in the morning on Days 2 and 3.
It may damage sperms and may harm the baby if used during pregnancy or breastfeeding.

Fact Box

Chemical Class

Phenylmorpholine Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Neurokinin-1 (NK1) Receptor Antagonists

Interaction with drugs

Taking Aprepep with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Primidone (Oral Route) Life-threatening

Primidone may reduce blood levels of Aprepitant. Do not consume Aprepitant with Primidone.

Pimozide (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and can be fatal. Do not consume Aprepitant with Pimozide.

Enzalutamide (Oral Route) Severe

Enzalutamide may reduce blood levels of Aprepitant. Do not consume Aprepitant with Enzalutamide.

Apalutamide (Oral Route) Severe

Apalutamide may reduce blood levels of Aprepitant. Do not consume Aprepitant with Apalutamide.

Ranolazine (Oral Route) Severe

Concurrent use may cause life-threatening disturbances in the heart rhythm. Aprepitant may raise blood levels of Ranolazine. watch out for symptoms of Aprepitant side effects such ... More

View all drug interactions

Patient concerns

NAUSEA AND VOMITING DUE TO COLD

Dr. Sunil Sekhri

Diabetology

Tab Domstal 1 tab Stat and keep yourself warm

Vomiting, nausea neck pain backside

Dr. Vijay Verma

ENT

Neck pain may be due to nausea NAD vomiting Visit physician for the same

I am in the first month of pregnancy and I am experiencing nausea, vomiting, stomach pain (moderate to severe) as well as discomfort. Current medications is Susten SR 200 (OD), Duvadilan retard (OD), Doxinate (BD), Folverine D (OD), Fertigyn 500 (1 amp weekly) and aciloc 150 (BD). What should I do to ease my situation. Please suggest

Dr. Suman Rao

Obstetrics and Gynaecology

The med suggested are to support of pregnancy and for acidity and nausea and vomiting. Continue the same. You can upgrade the med for vomiting after consulting your

Vomiting nausea problem and fever

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

User feedback

What are you using Aprepep Capsule for?

Vomiting

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FAQs

What are Aprepep 125mg Capsule capsules/ what is Aprepep 125mg Capsule used for?

Aprepep 125mg Capsule is used in adults in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) or in some cases after a surgery

How does Aprepep 125mg Capsule work?

Aprepep 125mg Capsule is an antiemetic that works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1086.
Aprepitant. [Accessed 28 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

Marketer details

Name: Intas Pharmaceuticals Ltd

Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Country of origin: India

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Aprepep 125mg Capsule

Product introduction

Uses of Aprepep Capsule

Side effects of Aprepep Capsule

Common side effects of Aprepep

How to use Aprepep Capsule

How Aprepep Capsule works

Safety advice

What if you forget to take Aprepep Capsule?

All substitutes

Quick tips

Fact Box

Interaction with drugs

Patient concerns

User feedback

FAQs

What are Aprepep 125mg Capsule capsules/ what is Aprepep 125mg Capsule used for?

How does Aprepep 125mg Capsule work?

Top Physicians

Want to share the information?

Disclaimer:

References

Marketer details

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