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Aplet 60mg Tablet

Apalutamide (60mg)

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Aplet 60mg Tablet is a medication used in the treatment of prostate cancer. It works by blocking the effects of testosterone on prostate cancer cells, which help slow down the growth and spread of prostate cancer. It is often used in combination with other therapies to treat prostate cancer.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 01 Oct 2026 | 01:02 AM (IST)

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Aplet 60mg Tablet

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General Information

Contains

Apalutamide (60mg)

Marketer

Glenmark Pharmaceuticals Ltd

The content is shown in English

Product introduction

Aplet 60mg Tablet may be taken with or without food. However, always take it in the dose and duration prescribed by your doctor. Also, continue taking this medicine for as long as your doctor prescribes it, as missing a dose or stopping the treatment prematurely can reduce its effectiveness and may impact overall treatment outcomes.

Some common side effects of this medicine include fatigue, skin rash, hypertension, hot flush, arthralgia, diarrhea, falls, and weight loss. These side effects mostly occur at the initial stage of the treatment and usually disappear within a few days with continued treatment. However, let your doctor know if any of these side effects get worse or bother you. The doctor may also monitor you regularly to check the effectiveness of the medicine.

Aplet 60mg Tablet is not suitable for everyone. To make sure it is safe for you, let your doctor know if you have a known history of allergic reactions to any of the ingredients of this medicine or have any other pre-existing medical conditions. Also, inform the doctor if you are taking, have recently taken, or might take any other medicines. This medicine is also contraindicated in pregnant or breastfeeding women, as it can cause harm to the developing fetus or nursing baby.

Uses of Aplet Tablet

Treatment of Prostate cancer

Benefits of Aplet Tablet

Treatment of Prostate cancer
Aplet 60mg Tablet blocks the effects of testosterone on cancer cells, which in turn slows down the growth and spread of the cancer. It helps to control the cancer progression and improves the patient's overall condition and quality of life.

Side effects of Aplet Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aplet

Decreased appetite
Fracture
Rash
Flushing (sense of warmth in the face, ears, neck and trunk)
Diarrhea
High blood pressure
Fatigue
Joint pain
Fall
Weight loss

How to use Aplet Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aplet 60mg Tablet may be taken with or without food.

How Aplet Tablet works

Prostate cancer cells depend on androgens to grow and survive. Even in cases where the cancer becomes resistant to standard hormonal therapies (castration-resistant), androgen receptors in the cancer cells continue to be active and promote cancer growth. Aplet 60mg Tablet targets these androgen receptors, blocks their activation, and prevents them from binding to androgens. This action inhibits the signaling pathway that drives the growth and proliferation of prostate cancer cells.

All substitutes for Aplet 60mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

If you have ever experienced a seizure, you must inform your doctor.
If you have ever suffered from a brain injury, stroke (within one year), or primary brain tumor, inform your doctor.
Inform your doctor if you have a history of cardiovascular problems.
Follow your doctor's instructions regarding the dosage, timing, and duration of the treatment.
Attend all follow-up visits with your doctor as scheduled.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Aplet 60mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Aplet 60mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Aplet 60mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Aplet 60mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Aplet 60mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Aplet 60mg Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Aplet with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Nevirapine (Oral Route)

Do not consume Nevirapine with Apalutamide. Apalutamide may reduce blood levels of Nevirapine.

Severe

Mifepristone (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Mifepristone.

Severe

Isoflurane (Inhalation Route)

Concurrent use should be avoided. Please consult with your doctor.

Severe

Hydroxychloroquine (Oral Route)

Concurrent use should be avoided. Please consult with your doctor.

Severe

Apixaban (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Apalutamide may increase the metabolism of Apixaban.

Frequently asked questions

What is Aplet 60mg Tablet used for?

Aplet 60mg Tablet is used to treat certain types of prostate cancer that are still growing even when testosterone levels are low (called castration-resistant prostate cancer), or that have spread to other parts of the body but are still sensitive to testosterone (called metastatic castration-sensitive prostate cancer). It helps slow down cancer growth and lowers the risk of it spreading further.

Can Aplet 60mg Tablet be used alone for prostate cancer treatment?

Your doctor may prescribe Aplet 60mg Tablet along with another treatment that lowers testosterone, such as surgery to remove the testicles, or medicines that block testosterone production. Testosterone fuels prostate cancer growth, so this product works best when testosterone levels are kept low.

Who should not take Aplet 60mg Tablet?

Individuals should not take Aplet 60mg Tablet if they are allergic to it or any of its ingredients. People with a history of severe allergic reactions, seizures, or certain heart problems should inform their doctor before starting the treatment. This product is for men only and should not be used by women or children.

What are the serious side effects of Aplet 60mg Tablet I should watch out for?

Some serious side effects of Aplet 60mg Tablet may include seizures, fainting, falls, fractures, severe skin rash, or allergic reactions such as swelling and trouble breathing. If you experience any of these symptoms, get medical help right away.

Can Aplet 60mg Tablet cause skin reactions or rashes?

Yes, some people may develop skin rashes or allergic reactions while taking Aplet 60mg Tablet. Severe skin rashes may include redness, blisters, or peeling. Contact your doctor immediately if you notice these symptoms.

Does Aplet 60mg Tablet affect bone strength or increase fracture risk?

Yes, Aplet 60mg Tablet can make bones weaker, especially when used with testosterone-lowering treatments. This may increase the risk of falls or bone fractures. Your doctor may recommend supplements or lifestyle changes to protect your bone health.

Can women or children take Aplet 60mg Tablet?

No, Aplet 60mg Tablet is meant for adult men only. It should not be used by women or children. Women who are pregnant or may become pregnant should not handle crushed or broken product, as it may harm the unborn baby.

How does Aplet 60mg Tablet help improve survival in prostate cancer?

Aplet 60mg Tablet helps by blocking signals that drive prostate cancer cells to grow and spread. Clinical studies indicate that it may delay cancer progression and support survival in men with advanced prostate cancer when used as prescribed along with hormone therapy.

What regular monitoring is needed during Aplet 60mg Tablet?

Your doctor will monitor your blood pressure, liver function, thyroid levels, and bone health during Aplet 60mg Tablet treatment. Regular medical visits help ensure that the product is working effectively and that any side effects are managed early.

Fact Box

Chemical Class

Phenylimidazolidines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Androgen Receptor Antagonists

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Anti Neoplastics

Cytostatic Hormone Antagonists

Aplet 60mg Tablet

Aplet 60mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Aplet Tablet

Benefits of Aplet Tablet

Side effects of Aplet Tablet

How to use Aplet Tablet

How Aplet Tablet works

All substitutes for Aplet 60mg Tablet

Apatide 60mg Tablet

Pryor Tablet

Apatide 60mg Tablet

Proapaci 60 Tablet

Pryor Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Nevirapine (Oral Route)

Mifepristone (Oral Route)

Isoflurane (Inhalation Route)

Hydroxychloroquine (Oral Route)

Apixaban (Oral Route)

Frequently asked questions

What is Aplet 60mg Tablet used for?

Can Aplet 60mg Tablet be used alone for prostate cancer treatment?

Who should not take Aplet 60mg Tablet?

What are the serious side effects of Aplet 60mg Tablet I should watch out for?

Can Aplet 60mg Tablet cause skin reactions or rashes?

Does Aplet 60mg Tablet affect bone strength or increase fracture risk?

Can women or children take Aplet 60mg Tablet?

How does Aplet 60mg Tablet help improve survival in prostate cancer?

What regular monitoring is needed during Aplet 60mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests