Apediol 2mg Tablet is a female sex hormone (estrogen). This is a type of hormone replacement therapy (HRT) that is used to treat symptoms associated with menopause (hot flushes, vaginal dryness, and itching), estrogen deficiency, and thinning of bones (osteoporosis).

Apediol 2mg Tablet is to be swallowed with water. It can be taken with or without food, but remember to take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.

The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, nausea, vomiting, and hair loss. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.

Uses of Apediol Tablet

Hormone replacement therapy

Benefits of Apediol Tablet

In Hormone replacement therapy

Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Apediol Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Apediol

Headache
Nausea
Breast pain
Abdominal cramp
Bloating
Vaginal spotting
Vomiting

How to use Apediol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Apediol 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Apediol Tablet works

Apediol 2mg Tablet contains a medication called estrogen (female sex hormone). It works by replacing estrogen that is normally produced by the body. In women who are undergoing or have attained menopause, it prevents symptoms such as hot flushes, vaginal burning, dryness, and itching, caused due to lack of estrogen.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Apediol 2mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Apediol 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

UNSAFE

Apediol 2mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

SAFE

Apediol 2mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Apediol 2mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Apediol 2mg Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Apediol 2mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Apediol 2mg Tablet may be needed. Please consult your doctor.
Use of Apediol 2mg Tablet is not recommended in patients who previously had liver disease and the liver function tests are still not normal and should not be given to women with severe hepatic disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Apediol 2mg Tablet

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Quick tips

You have been prescribed Apediol 2mg Tablet as a part of hormone replacement therapy to relieve symptoms of menopause.
It may also be used for preventing osteoporosis in postmenopausal women who are at high risk of fractures.
Take it at the same time everyday to help you remember to take it.
Inform your doctor if you experience any unusual vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while taking Apediol 2mg Tablet.
It may increase the risk of breast cancer. Have regular breast examinations.
Stop taking this medicine and inform your doctor immediately if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain, or changes in vision. These could be symptoms of a blood clot in a vein.

Fact Box

Chemical Class

Estradiol Congeners

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Estrogens

Interaction with drugs

Taking Apediol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Mycophenolate mofetil (Oral Route) Severe

Mycophenolate mofetil may reduce the efficacy of Estradiol. Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It ... More

Saquinavir (Oral Route) Severe

Concurrent use may result in contraceptive failure. It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may monitor your treat... More

Darunavir (Oral Route) Severe

If used together, Darunavir may affect blood levels of Estradiol. It is recommended to use barrier methods (like condoms), IUDs, or a depot for contraception. Your doctor may moni... More

Lenalidomide (Oral Route) Severe

Concurrent use may increase the risk of formation of blood clots. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observatio... More

Thalidomide (Oral Route) Severe

Concurrent use may increase the risk of blood clots. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

View all drug interactions

Patient concerns

I have been told by doctors I have cystitis also simple cyst in right ovary . What should I be doing its been two years I have this issue

Dr. Megha Tuli

Obstetrics and Gynaecology

Hi PATIENT hormone therapy helps with cysts. Ask your doctor for a hormone replacement.

I am a male to female transsexual and I need Bilateral Orchiectomy at a fair cost I am already on hormone replacement therapy for 2 years anti androgen/spirnolactone (Aldactone) and estrodiol valerate progynova, I need to have bilateral orchiectomy at the cheapest option

Dr. Deepak Kumar Soni

Ayurveda

Hi Kindly consult to your nearest doctor

What are the side effects of prolonged usage of thyronorm medicine as I am having hypothyroidism since the last 20 years and I am taking the medicine since then . Thanks

Dr. Sfurti Mann

Internal Medicine

It is thyroxin hormone given as replacement of the hormone thyroxin which your body is not producing adequately. If it is being taken in the correct dose maintains your TSH in normal range then it has no side effects.

FAQs

What is Apediol 2mg Tablet and what is it used for?

Apediol 2mg Tablet contains Estradiol, which is an estrogen hormone. It helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness in women. It is also used to prevent osteoporosis (thinning and weakening of bones) in postmenopausal women, who are at high risk of fractures and have limited treatment choice.

What if I miss a dose of Apediol 2mg Tablet?

If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule.

What are the most common side effects which I may experience while taking Apediol 2mg Tablet?

The common side effects associated with Apediol 2mg Tablet are lower abdominal pain, periods pain, breast tenderness, endometrial hyperplasia (thickening of uterus lining) and vaginal discharge. Most of these symptoms are temporary. However, if these persist, check with your doctor as soon as possible.

What can I take for estrogen deficiency?

For estrogen deficiency, treatment is based on the underlying cause. Your doctor may choose from a variety of medications depending upon your age and clinical conditions. The medications will also depend upon whether you are estrogen deficient or have high progesterone levels.

Who should not take Apediol 2mg Tablet?

Apediol 2mg Tablet should not be taken by patients who have unusual vaginal bleeding, liver problems, or bleeding disorder. It should also be avoided to patients who are pregnant or are allergic to Apediol 2mg Tablet. Patients who have had uterus or breast cancer, had a stroke or heart attack, or currently have or had blood clots should also avoid this medicine.

Does Apediol 2mg Tablet cause weight gain?

Apediol 2mg Tablet may cause either weight gain or weight loss. This is a common side effect of Apediol 2mg Tablet. However, exercising regularly and eating a healthy nutritious diet can help you prevent weight gain. In case you notice weight gain and it bothers you, consult your doctor.

How should Apediol 2mg Tablet be taken?

Apediol 2mg Tablet tablets should be taken exactly as advised by your doctor. Swallow the tablets whole with water. You can take it at any time of the day but take it at the same time each day.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1173-75.
Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 500-501.
MedIndia. Estradiol. [Accessed 03 Apr. 2019] (online) Available from:
Estradiol. Rockaway, New Jersey: Warner Chilcot; 2009. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 01 Apr. 2019] (online) Available from:
CiplaMed. Estradiol valerate [Prescribing Information]. [Last Revised: February 2021]. [Accessed 24 June 2023]. (online) Available from:

Marketer details

Name: Apellon Biotech

Address: No. 8/2, Sarvpriya Vihar, Sarvapriya Vihar, New Delhi-110016, Delhi, India

Country of origin: India

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