Amphocil 100mg Injection
Prescription Required
Product introduction
Amphocil 100mg Injection is a medicine used to treat severe fungal infections that affect the blood, lungs, brain, or other internal organs. It is also used for a parasitic disease called visceral leishmaniasis (kala azar). It works by killing the fungus or parasite that causes the infection.
Amphocil 100mg Injection is generally given in a hospital or clinic by a doctor or nurse through a drip into the vein. It is important to complete the full course as advised, even if you start feeling better, because stopping too early can make the infection come back or become harder to treat. Drink plenty of fluids and rest well to help you get the best results from the treatment.
Common side effects of Amphocil 100mg Injection include fever, chills, headache, nausea, or tiredness after the injection, especially with the first few doses. These usually get better as your body adjusts. You may also notice kidney-related problems, so your doctor will check your blood and urine often. If you experience any symptoms that persist or worsen, inform your doctor.
Amphocil 100mg Injection should be taken only under strict medical guidance. People with kidney disease, heart problems, or electrolyte imbalances need extra care, as the medicine can make these conditions worse. It is important not to take any other medicines, especially painkillers or antibiotics, without your doctor’s approval because they may increase side effects. Pregnant or breastfeeding women should use it only if clearly needed and advised by the doctor.
Uses of Amphocil Injection
- Treatment of Severe fungal infections
- Kala-azar
- Treatment of Leishmaniasis.
Benefits of Amphocil Injection
In Treatment of Severe fungal infections
Amphocil 100mg Injection is a strong medicine used when fungal infections become very serious and spread inside the body. It works by damaging the wall of the fungus, thereby killing it. Even though it can sometimes cause side effects, it is often the most reliable treatment for dangerous infections like those affecting the lungs, blood, or brain.
In Kala-azar
Kala azar is a disease caused by leishmania parasites mainly by the bite of infected sandflies. Amphocil 100mg Injection helps to kill the infection causing parasites and helps to treat the infection. This medicine is given by a doctor or nurse and should not be self-administered. It usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all the parasites are killed and do not become resistant.
In Treatment of Leishmaniasis.
Visceral leishmaniasis, also known as kala azar, is a serious infection caused by parasites that affect internal organs like the liver, spleen, and bone marrow. Amphocil 100mg Injection helps is especially helpful when other medicines do not work or the disease comes back. It kills the parasite by damaging its protective covering, which helps patients recover faster and improves their chances of a complete recovery.
Side effects of Amphocil Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Amphocil
- Nausea
- Vomiting
- Chills
- Headache
- Anemia (low number of red blood cells)
- Abnormal liver function tests
- Decreased magnesium level in blood
- Diarrhea
- Decreased appetite
- Hypotension (low blood pressure)
- Skin rash
- Nephrocalcinosis
- Increased creatinine level in blood
- Abnormal renal function tests
- Renal tubular acidosis
- Injection site reactions (pain, swelling, redness)
- Increased potassium level in blood
How to use Amphocil Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Amphocil Injection works
Amphocil 100mg Injection works by binding to ergosterol, an essential component of fungal and parasite cell membranes. This binding creates pores in the membrane, causing leakage of vital cell contents and ultimately leading to cell death. This action makes it highly effective against a wide range of fungi and the parasite that causes kala azar.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Amphocil 100mg Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Amphocil 100mg Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Amphocil 100mg Injection during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Amphocil 100mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CAUTION
Amphocil 100mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Amphocil 100mg Injection may be needed. Please consult your doctor.
Liver
CAUTION
Amphocil 100mg Injection should be used with caution in patients with liver disease. Dose adjustment of Amphocil 100mg Injection may be needed. Please consult your doctor.
What if you forget to take Amphocil Injection?
If you miss a dose of Amphocil 100mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Amphocil 100mg Injection
₹10130/Injection
Ampholip 100mg Injection
Bharat Serums & Vaccines Ltd
₹10734.29/injection
2% cheaper
Amphomul 100mg Injection
Bharat Serums & Vaccines Ltd
₹8500/injection
23% cheaper
Quick tips
- Amphocil 100mg Injection should always be taken in a hospital or clinic under medical supervision.
- Do not skip or stop doses even if you start feeling better, as the infection may come back.
- Drink plenty of fluids unless your doctor advises otherwise, to help protect your kidneys.
- Report symptoms like difficulty breathing, chest pain, or reduced urine output immediately.
- Do not take any other medicines, including herbal supplements, without consulting your doctor.
Fact Box
Chemical Class
Aminoglycosides {Polyenes}
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Polyene Antifungals
Interaction with drugs
Taking Amphocil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Your doctor may monitor your blood cell count for toxicity of medicines and adjust the doses as per the observations.
Concurrent use may cause damage to the kidneys and decreased
Your doctor may monitor your kidney function regularly.
Concurrent use may increase the risk of kidney dysfunction.
Do not consume Tenofovir disoproxil fumarate with Amphotericin B. If concurrent use is essential, your doctor may monitor your kidney function closely.
Concurrent use may increase
If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Concurrent use may potentially damage the kidneys.
If concurrent use is essential, your doctor may closely monitor your kidney's functioning and overall treatment.
Concurrent use may increase the risk of kidney impairment.
Patient concerns
FAQs
What is Amphocil 100mg Injection used for?
Amphocil 100mg Injection is used to treat very serious fungal infections in the blood, lungs, brain, or other organs, and also for a parasitic disease called visceral leishmaniasis (kala azar).
How is it given?
Amphocil 100mg Injection is given by a doctor or nurse as a drip into the vein in a hospital or clinic. You should not self-administer this medicine on your own.
Why do I need to stay in the hospital for this medicine?
Because Amphocil 100mg Injection can cause side effects, your doctor will monitor you closely with regular check-ups and blood tests to make sure the treatment is safe and effective.
How long will I need this treatment?
The duration depends on the type and severity of your infection. Your doctor will decide how many doses you need. It is important not to miss or stop treatment early.
Can I take other medicines along with Amphocil 100mg Injection?
Always inform your doctor about all medicines or supplements you are taking. Some drugs can interact and increase the risk of side effects.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 29 Mar. 2019] (online) Available from:
- Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1424.
- Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1571-75.
- Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 836-38.
- Amphotericin B [Drug Label]. San Dimas, California: Gilead Sciences, Inc.; 2000. [Accessed 20 Sept. 2025] (online) Available from:
- Amphotericin B [Prescribing Information]. Big Flats, NY: XGen Pharmaceuticals DJB, Inc.; 2022. [Accessed 20 Sept. 2025] (online) Available from:
Marketer details
Name: Criticare Laboratories Pvt Ltd
Address: 163/2, Reservoir Street, Basavanagudi, Bangalore-560004.
Country of origin: India
Expires on or after: December, 2025
A licensed vendor partner from your nearest location will deliver Amphocil 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: December, 2025
A licensed vendor partner from your nearest location will deliver Amphocil 100mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹11000 8% OFF
₹10130
Inclusive of all taxes
1.0 Injection in 1 vial
Online payment only
Not returnable Read policy
Get by Tuesday, 23 September
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