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Last updated on:
01 Aug 2019 | 11:57 AM (IST)
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Amitop 250 mg Injection

Prescription Required

Overview

Amitop Injection side effects

Common
  • Injection site reactions (pain, swelling, redness)
  • Increased heart rate
  • Dryness in mouth
  • Constipation
  • Weight gain
  • Difficulty in urination
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Amitop Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Amitop Injection works

Amitop 250 mg Injection is a tricyclic antidepressant. It works by increasing the levels of chemical messengers in the brain that help in regulating mood and treat depression. It also stops the movement of pain signals from nerves to the brain thereby relieving neuropathic pain (pain from damaged nerves).

Amitop Injection related warnings

Alcohol
UNSAFE
Amitop 250 mg Injection may cause excessive drowsiness with alcohol
Pregnancy
CONSULT YOUR DOCTOR
Amitop 250 mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Amitop 250 mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amitop 250 mg Injection may cause side effects which could affect your ability to drive.
Amitop 250 mg Injection may impair your alertness which may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amitop 250 mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amitop 250 mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Amitop 250 mg Injection should be used with caution in patients with liver disease. Dose adjustment of Amitop 250 mg Injection may be needed. Please consult your doctor.
Use of Amitop 250 mg Injection is not recommended in patients with severe liver disease.

What if you miss a dose of Amitop Injection?

If you miss a dose of Amitop 250 mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • It may take 4 to 6 weeks for Amitop 250 mg Injection to start working. Keep taking it as prescribed.
  • It may cause sleepiness. Take it at bedtime and do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid consuming alcohol when taking Amitop 250 mg Injection as it may cause excessive sleepiness.
  • Monitor your weight during the treatment as this medicine can cause weight gain and increased appetite.
  • It may cause sudden drop in your blood pressure. Rise slowly if you have been sitting or lying down.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.

Interaction with Drugs

Taking Amitop with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Eurolam
SERIOUS
Brand(s): Psycolith
SERIOUS
Brand(s): Zosert
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Risure
SERIOUS
Brand(s): Psycopan
SERIOUS
Brand(s): Leparox, Prx
SERIOUS
Brand(s): Panik
SERIOUS
Brand(s): Vlx
SERIOUS
Brand(s): Tremash
SERIOUS

Patient Concerns

Questions Related to Amitop

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Have constant mild head ache from past 1 year. Generally, starts from the right side of the head
Dr. Vikas Sharma
Neurologist
Get ct head Start tab amitop 10 mg hs
I am having constant head aches from past 1 year generally starts from the right side of the head
Dr. Vikas Sharma
Neurologist
Do ct head Start tab amitop 10 mg at nite daily
arrow
Do you have any questions related to Amitop 250 mg Injection?

FAQs

Q. Is there anything I need to be careful about while on therapy with Amitop?

Amitop may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Q. Can the use of Amitop affect my sex life?

Yes, Amitop can affect sex life in both men and women. It may cause decreased sexual desire or you may experience discomfort during intercourse. Men may experience inability to develop or maintain an erection during sexual activity and may be unable to have an orgasm. If you notice these symptoms, do not stop taking the medicine but consult your doctor.

Q. I have been taking Amitop for depression since a week and now I feel that my life has come to end and sometimes I want to harm myself. What should I do? Is it because of the medicine?

You should immediately consult your doctor or go to the hospital. Your suicidal tendencies may have increased because of the medicine or because of your disease. This is more common in people who previously had suicidal tendencies or are young adults (less than 25 years old). Amitop takes about 2 weeks to show its effect but may take longer, however, it may differ from individual to individual. Therefore, when you start taking Amitop, you may have thoughts about killing or harming yourself.

Q. Can Amitop cause urinary problems?

Yes, Amitop can cause urinary problems. It is more commonly seen in elderly patients who are more than 65 years old. The patient may develop urinary tract infection or may complain of weakness. You should consult your doctor if you develop these symptoms.

Q. If my pain is not relieved, can I take more than the recommended dose?

No, Amitop should be strictly used only as prescribed by the doctor. If the dose exceeds, you may develop drowsiness, confusion, difficulty in speech, dry mouth, tiredness, difficulty in walking, fever, difficulty in breathing, blue discoloration of the skin and decreased heartbeat. Your pain may not be relieved because Amitop takes about 2 weeks to show its effect, but may take longer. The time differs from individual to individual. Consult your doctor if your symptoms are not relieved.

Q. Does Amitop cause any effect on pregnancy or the newborn?

Do not take Amitop during pregnancy unless recommended by the doctor. If you take this medicine during the last trimester of the pregnancy, the newborn may develop symptoms such as irritability, rigidity, irregular body movements, irregular breathing, poor drinking, loud crying, difficulty in urinating and constipation.

Q. I have been prescribed Amitop for pain. When will I start feeling better?

You may start feeling better after 2 weeks of starting Amitop. However, it may take 4-6 weeks to see full benefits of the medicine.

Q. Can I stop taking Amitop when my pain is relieved?

No, do not stop taking Amitop even if the pain is relieved. Take Amitop as per your doctor’s advice. Stopping the medicine suddenly may cause unpleasant symptoms like headache, feeling unwell, sleeplessness and irritability. Consult your doctor for duration of the treatment since the dose of Amitop needs to be reduced gradually.
Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Stahl SM, editor. Amitriptyline. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 25-30.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 58-59.
  3. U.S. National Library of Medicine. Amitriptyline. [Accessed 19 Mar. 2019] (online) Available from:External Link
  4. Amitriptyline. Wilmington, Delaware: Zeneca Pharmaceuticals; 2000. (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Thrift Pharmaceuticals Private Limited, Kh--136, raipur Industrial Area Behind Pritam International, Roorkee-247661, Uttarakhand, India
A licensed pharmacy from your nearest location will deliver Amitop 250mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your prescription and the availability of this medicine.
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