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Amantrel Capsule

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Amantrel Capsule is used alone or in combination with other medicines to treat Parkinson’s disease. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Amantrel Capsule helps in improving muscle control and reducing stiffness by affecting specific brain chemicals. Take Amantrel Capsule as prescribed by your doctor, with or without food, preferably at the same time each day, to maintain a steady level of the medicine in your body. It can also be used to treat drug-induced movement disorders.


Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.


Some common side effects of Amantrel Capsule include nausea, dizziness, and insomnia (difficulty sleeping). If you experience dizziness, rise slowly and do not drive or do anything that requires mental focus until you know how this medicine affects you.


This medicine may put you at a higher risk of having seizures, so talk to your doctor if you have any history of seizures or if you are taking any medication for seizures. Pregnant or breastfeeding women should consult a doctor before taking this medicine to make sure it is safe for them.


Uses of Amantrel Capsule

Benefits of Amantrel Capsule

In Treatment of Parkinson's disease

Amantrel Capsule helps improve muscle control, reduce stiffness, and enhance mobility in individuals with Parkinson's disease. This supports better coordination, reduced tremors, and improved overall daily functioning. When used regularly as advised by the doctor, it eases movement-related difficulties and improves overall quality of life.

Side effects of Amantrel Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amantrel

  • Nausea
  • Dizziness
  • Insomnia (difficulty in sleeping)

How to use Amantrel Capsule

Take this medicine in the dose and duration as advised by your doctor. Amantrel Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Amantrel Capsule works

Amantrel Capsule works by increasing the levels of certain brain chemicals, such as dopamine, that help control movement and coordination. It helps improve muscle function, reduce stiffness, and enhance mobility in people with Parkinson’s disease and other movement disorders. It restores dopamine balance in the brain, making it easier to perform daily activities with better control and comfort.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amantrel Capsule.
Pregnancy
CONSULT YOUR DOCTOR
Amantrel Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Amantrel Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amantrel Capsule may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Amantrel Capsule should be used with caution in patients with kidney disease. Dose adjustment of Amantrel Capsule may be needed. Please consult your doctor.
Use of Amantrel Capsule is not recommended in patients with severe kidney disease.
Liver
CAUTION
Amantrel Capsule should be used with caution in patients with liver disease. Dose adjustment of Amantrel Capsule may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

What if you forget to take Amantrel Capsule?

If you miss a dose of Amantrel Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Amantrel Capsule
₹17.4/Capsule
Amantril 100mg Capsule
Aci Pharma Pvt Ltd
₹9.6/capsule
45% cheaper
Amdatime 100mg Capsule
Shilpa Medicare Ltd
₹15/capsule
14% cheaper
Neaman 100mg Capsule
Nestor Pharmaceuticals
₹3.88/capsule
78% cheaper
Amantide Capsule
Chemo Healthcare Pvt Ltd
₹19.6/capsule
13% costlier
Comantrel 100 Capsule
Consern Pharma Limited
₹10.7/capsule
39% cheaper

Quick tips

  • Amantrel Capsule may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Amantrel Capsule may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
  • Inform your doctor if you experience compulsive behaviors like gambling, increased sexual urges, binge eating, or overspending, as Amantrel Capsule may affect dopamine levels and cause impulse control issues.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Synthetic Tricyclic Amine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
NMDA (N-methyl-D-aspartate) Receptor Antagonists

Interaction with drugs

Taking Amantrel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. If taken together, A... More
Careful consideration is advised when taking Bupropion with Amantadine. If concurrent use is essential, watch out for symptoms such as shortness of breath, headache, nausea or blur... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More

Patient concerns

Is there have any medicine 4 PD Hi sir ,good afternoon My father is suffering from Parkinson's disease since last 3years. Recently he is taking syndopa plus revemer 3,Ropark 25 and amantrel I am not getting any positive results
Dr. Deepak Kumar Soni
Ayurveda
https://www.1mg.com/otc/zandopa-powder-otc237392
Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months

User feedback


FAQs

Can Amantrel Capsule get you high?

The use of Amantrel Capsule may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced, then dose reduction or tapered discontinuation should be considered.

Is Amantrel Capsule a dopamine agonist?

Yes, Amantrel Capsule is a dopamine agonist. Dopamine is needed to control movements in the brain. Amantrel Capsule works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Does Amantrel Capsule cause fatigue?

Yes, Amantrel Capsule causes fatigue and sleepiness, which may affect some patients’ ability to drive and operate machinery safely.

Can I take Amantrel Capsule any time during the day? Should the dose be taken before meal?

Amantrel Capsule can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you remember when to take your medicine.

Is Amantrel Capsule used for pain?

Though it is not an approved use, Amantrel Capsule is effective in relieving pain related to nerve disorders. Amantrel Capsule is a prescription medicine, and you should take it for the relief of pain only if advised by the doctor.

What happens when I stop taking Amantrel Capsule?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Amantrel Capsule may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reactions, stupor, anxiety, depression, or slurred speech.

Can Amantrel Capsule cause weight loss?

A decrease in weight and body mass index may occur with continued Amantrel Capsule usage. If you have any concerns regarding weight loss, consult your doctor or a nutritionist.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
  4. Amantadine [Prescribing Information]. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018]. [Accessed 19 Jun. 2019] (online) Available from: External Link
  5. Amantadine hydrochloride [Prescribing Information]. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014. [Accessed 19 Jun. 2019] (online) Available from: External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from: External Link
  7. Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022. [Accessed 09 Jun 2023] (online) Available from: External Link
  8. Amantadine Hydrochloride [Product Information]. Ahmedabad, Gujarat: Zydus Lifesciences Ltd.; 2025. [Accessed 14 Mar. 2025] (online) Available from: External Link

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

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