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Amantad ER 129 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Amantad ER 129 Tablet is used alone or in combination with other medicines to treat Parkinson’s disease. It works by increasing the levels of a chemical called dopamine in the brain, which is important for controlling movement.

Amantad ER 129 Tablet helps in improving muscle control and reducing stiffness by affecting specific brain chemicals. Take Amantad ER 129 Tablet as prescribed by your doctor, with or without food, preferably at the same time each day, to maintain a steady level of the medicine in your body. It can also be used to treat drug-induced movement disorders.


Take this medicine in the dose and duration as advised by your doctor. If you have missed a dose, take it as soon as you remember it. You should finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor.


Some common side effects of Amantad ER 129 Tablet include nausea, dizziness, and insomnia (difficulty sleeping). If you experience dizziness, rise slowly and do not drive or do anything that requires mental focus until you know how this medicine affects you.


This medicine may put you at a higher risk of having seizures, so talk to your doctor if you have any history of seizures or if you are taking any medication for seizures. Pregnant or breastfeeding women should consult a doctor before taking this medicine to make sure it is safe for them.


Uses of Amantad Tablet

Benefits of Amantad Tablet

In Treatment of Parkinson's disease

Amantad ER 129 Tablet helps improve muscle control, reduce stiffness, and enhance mobility in individuals with Parkinson's disease. This supports better coordination, reduced tremors, and improved overall daily functioning. When used regularly as advised by the doctor, it eases movement-related difficulties and improves overall quality of life.

Side effects of Amantad Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amantad

  • Nausea
  • Dizziness
  • Insomnia (difficulty in sleeping)

How to use Amantad Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amantad ER 129 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amantad Tablet works

Amantad ER 129 Tablet works by increasing the levels of certain brain chemicals, such as dopamine, that help control movement and coordination. It helps improve muscle function, reduce stiffness, and enhance mobility in people with Parkinson’s disease and other movement disorders. It restores dopamine balance in the brain, making it easier to perform daily activities with better control and comfort.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amantad ER 129 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Amantad ER 129 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Amantad ER 129 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amantad ER 129 Tablet may cause side effects which could affect your ability to drive.
Kidney
CAUTION
Amantad ER 129 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Amantad ER 129 Tablet may be needed. Please consult your doctor.
Use of Amantad ER 129 Tablet is not recommended in patients with severe kidney disease.
Liver
CAUTION
Amantad ER 129 Tablet should be used with caution in patients with liver disease. Dose adjustment of Amantad ER 129 Tablet may be needed. Please consult your doctor.
It may cause a transient increase in liver enzymes.

What if you forget to take Amantad Tablet?

If you miss a dose of Amantad ER 129 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Amantad ER 129 Tablet may cause blurring of vision or affect mental ability. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Amantad ER 129 Tablet may put you at a higher risk of having seizures. Talk to your doctor if you have a history of seizures or are taking medication for it.
  • Inform your doctor if you experience compulsive behaviors like gambling, increased sexual urges, binge eating, or overspending, as Amantad ER 129 Tablet may affect dopamine levels and cause impulse control issues.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Synthetic Tricyclic Amine Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
NMDA (N-methyl-D-aspartate) Receptor Antagonists

Interaction with drugs

Taking Amantad with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Memantine with Amantadine. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. If taken together, A... More
Careful consideration is advised when taking Bupropion with Amantadine. If concurrent use is essential, watch out for symptoms such as shortness of breath, headache, nausea or blur... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More
If concurrent use is essential, watch out for symptoms such as constipation, confusion or psychosis and consult your doctor if you experience them. They may monitor your treatment ... More

Patient concerns

Parkinson's disease tremors ,Insomnia.
Dr. Ravi Shankar M.
Ayurveda
Use Dhanadanayanadi kashayam 15ml twice a day with 15 ml water before food and Zandopa 10 grams twice a day witk milk after food and Tab Dhanvantari Vati 1-0-1 after food for 2 months
Parkinson's disease for 25 yrs. Taking allopathy Suggestions needed
Dr. Deepak Kumar Soni
Ayurveda
Kindly consult to any good Ayuvedic Panchkarma center. Panchkarma therapy will give you some result .

FAQs

Can Amantad ER 129 Tablet get you high?

The use of Amantad ER 129 Tablet may cause impulse control disorders in which you may have strong urges to gamble, increased sexual urges, intense urges to spend money, binge eating, and other intense urges. Additionally, there is the inability to control these urges. If such symptoms are experienced, then dose reduction or tapered discontinuation should be considered.

Is Amantad ER 129 Tablet a dopamine agonist?

Yes, Amantad ER 129 Tablet is a dopamine agonist. Dopamine is needed to control movements in the brain. Amantad ER 129 Tablet works by increasing the amount of dopamine, thereby helping in controlling the movements in Parkinson’s disease.

Does Amantad ER 129 Tablet cause fatigue?

Yes, Amantad ER 129 Tablet causes fatigue and sleepiness, which may affect some patients’ ability to drive and operate machinery safely.

Can I take Amantad ER 129 Tablet any time during the day? Should the dose be taken before meal?

Amantad ER 129 Tablet can be taken at any time during the day, with or without food. Try to take the medicine at about the same time each day, as directed by your doctor. Taking your medicine at the same time each day will have the best effect. It will also help you remember when to take your medicine.

Is Amantad ER 129 Tablet used for pain?

Though it is not an approved use, Amantad ER 129 Tablet is effective in relieving pain related to nerve disorders. Amantad ER 129 Tablet is a prescription medicine, and you should take it for the relief of pain only if advised by the doctor.

What happens when I stop taking Amantad ER 129 Tablet?

Do not stop taking this medicine or lower the dose without first checking with your doctor. If required, your doctor will gradually reduce the amount you take each day before stopping it completely. Abruptly stopping Amantad ER 129 Tablet may result in worsening of Parkinsonism. It may also cause delirium, agitation, delusions, hallucinations, paranoid reactions, stupor, anxiety, depression, or slurred speech.

Can Amantad ER 129 Tablet cause weight loss?

A decrease in weight and body mass index may occur with continued Amantad ER 129 Tablet usage. If you have any concerns regarding weight loss, consult your doctor or a nutritionist.

Related ayurvedic ingredients

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 477.
  2. Standaert DG, Roberson ED. Treatment of Central Nervous System Degenerative Disorders. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 619.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 48-49.
  4. Amantadine [Prescribing Information]. Bridgewater, New Jersey: Vertical Pharmaceuticals, LLC; 1966 [revised Feb. 2018]. [Accessed 19 Jun. 2019] (online) Available from: External Link
  5. Amantadine hydrochloride [Prescribing Information]. North Ryde, New South Wales: NOVARTIS Pharmaceuticals Australia Pty Limited; 2014. [Accessed 19 Jun. 2019] (online) Available from: External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from: External Link
  7. Amantadine Hydrochloride [Product Information]. Maple Grove, MN: Upsher-Smith Laboratories, LLC; 2022. [Accessed 09 Jun 2023] (online) Available from: External Link
  8. Amantadine Hydrochloride [Product Information]. Ahmedabad, Gujarat: Zydus Lifesciences Ltd.; 2025. [Accessed 14 Mar. 2025] (online) Available from: External Link

Marketer details

Name: Mesmer Pharmaceuticals
Address: 202/6, Lane No. 30, Phase- II, IDA, Cherlapally, Hyderabad, Telangana, 500051, India
Country of origin: India
Expires on or after: August, 2025

A licensed vendor partner from your nearest location will deliver Amantad ER 129 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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