Alkepin 10mg Tablet

Asenapine (10mg)

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Alkepin 10mg Tablet is used in the treatment of schizophrenia (a mental disorder that can result in hallucinations or delusions and also adversely affects a person’s ability to think and behave) and mania. It can also be used to treat bipolar disorder.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 May 2026 | 05:19 PM (IST)

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General Information

Contains

Asenapine (10mg)

Marketer

Alkem Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Alkepin 10mg Tablet should be taken on an empty stomach. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, increased saliva production, and taste change. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may increase your weight. However, modifying your lifestyle by having a healthy diet and exercising regularly can reduce this side effect.

Before taking this medicine it is important to inform your doctor if your suffering from high body temperature and muscle stiffness (neuroleptic malignant syndrome), have had abnormal tongue or face movements (dyskinesia), heart disease, diabetes, Parkinson’s disease, dementia, fits (epilepsy), difficulty in swallowing (dysphagia), or liver problems.

Uses of Alkepin Tablet

Benefits of Alkepin Tablet

Mania
Mania means extremely excited or elevated mood. Alkepin 10mg Tablet helps calm the mood and relax the nerves. This stabilises the mood and prevents the symptoms of mania from recurring again. Taking Alkepin 10mg Tablet will ensure that you have a better social life and are able to do daily activities more comfortably.

Side effects of Alkepin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alkepin

Dizziness
Dystonia (involuntary muscle contractions)
Increased saliva production
Taste change
Akathisia (inability to stay still)
Abnormal involuntary movements
Anxiety
Nausea
Parkinsonism
Sleepiness
Weight gain

How to use Alkepin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alkepin 10mg Tablet is to be taken on an empty stomach.

How Alkepin Tablet works

Alkepin 10mg Tablet is an atypical antipsychotic. It works by modulating the action of certain chemical messengers in the brain that affect thoughts.

Quick tips

Alkepin 10mg Tablet should be taken as per dose and duration suggested by the doctor.
It is advisable not to eat or drink anything for 10 minutes after taking the medicine.

Safety advice

Alcohol

UNSAFE

Do not drink alcohol while you are taking this medicine. Alkepin 10mg Tablet may cause excessive drowsiness when taken with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Alkepin 10mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Alkepin 10mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Alkepin 10mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Alkepin 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Limited information is available on use of Alkepin 10mg Tablet in patients with end stage kidney disease.

Liver

CAUTION

Alkepin 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Alkepin 10mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Alkepin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Asenapine.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Hydroxyzine (Oral Route)

Do not consume Hydroxyzine with Asenapine.

Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

How long does it take for Alkepin 10mg Tablet to work?

Like many medicines, Alkepin 10mg Tablet does not work straight away. You might start feeling more calm and relaxed after a few weeks of taking this medicine.

Why has Alkepin 10mg Tablet been prescribed?

Alkepin 10mg Tablet is an antipsychotic drug used to treat manic episodes and schizophrenia, a mood disorder. It shortens the time to recovery and prevents mania from returning.

How many times a day can I take Alkepin 10mg Tablet?

Alkepin 10mg Tablet must be taken twice a day, once in the morning and once in the evening, e.g., after breakfast and dinner or as prescribed by your doctor.

Does Alkepin 10mg Tablet cause sleepiness?

Somnolence (sleepiness) is a common side effect of Alkepin 10mg Tablet. You should refrain from indulging in driving and heavy activities during your treatment. It is better to talk to your doctor if you experience sleep problems while taking Alkepin 10mg Tablet.

Is Alkepin 10mg Tablet addictive?

No, Alkepin 10mg Tablet is not addictive in nature. No habit-forming potential has been seen with its use. Always follow your doctor's advice regarding the duration of its use.

Does Alkepin 10mg Tablet affect blood sugar level?

If you have diabetes you may need to check your blood sugar (glucose) more frequently, as this medicine may affect the levels of sugar in your blood. Your doctor will be able to advise you about this.

Can I drink alcohol while taking Alkepin 10mg Tablet?

It is recommended that people taking this medicine should not drink alcohol. This is because Alkepin 10mg Tablet is an antipsychotic and taking it with alcohol can cause severe drowsiness. This can lead to falls and accidents. Also, drinking alcohol may make mania, depression, and anxiety worse. Discuss any concerns you have with your doctor, pharmacist, or nurse.

I am experiencing a change in my taste after the start of the treatment with Alkepin 10mg Tablet. Any tips to reduce it?

A change in taste is a common side-effect of this medicine. Rinse your mouth with a solution of salt and bicarbonate of soda before mealtimes to neutralize the bad taste in your mouth. You may also add some extra flavor or seasonings to your food.

Can I take fluoxetine with Alkepin 10mg Tablet?

No, you should avoid taking fluoxetine with Alkepin 10mg Tablet. This is because fluoxetine may cause an increase in levels of Alkepin 10mg Tablet in the body which may increase the medicine's side effects. Always consult your doctor before taking any other medications along with Alkepin 10mg Tablet. Self-medication can be risky.

Is Alkepin 10mg Tablet FDA approved?

Yes, Alkepin 10mg Tablet is approved by FDA

Is Alkepin 10mg Tablet a narcotic, or controlled substance?

Alkepin 10mg Tablet is not narcotic, controlled substance

Is Alkepin 10mg Tablet addictive?

Alkepin 10mg Tablet is not addictive

Can I take Xanax or Benadryl with Saphris?

Xanax (alprazolam) and Benadryl when taken with Saphris (asenapine) may lead to increased side effects such as drowsiness, dizziness, and difficulty concentrating

Does Alkepin 10mg Tablet cause weight gain?

Alkepin 10mg Tablet can cause weight gain.

Fact Box

Chemical Class

Dibenzo- oxepino pyrroles

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Atypical Antipsychotics

References

Stahl SM, editor. Asenapine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 65-70.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 87.
Asenapine maleate. Everard Close, St Albans: Lundbeck Limited; 2010 [08 Feb. 2018]. [Accessed 04 Feb. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Asenapine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Alkem Laboratories Ltd
Address: Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Alkepin 10mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Alkepin Tablet

Benefits of Alkepin Tablet

Side effects of Alkepin Tablet

How to use Alkepin Tablet

How Alkepin Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Domperidone (Oral Route)

Amiodarone (Oral Route)

Hydroxyzine (Oral Route)

Amiodarone (Injection Route)

Artemether (Injection Route)

Frequently asked questions

How long does it take for Alkepin 10mg Tablet to work?

Why has Alkepin 10mg Tablet been prescribed?

How many times a day can I take Alkepin 10mg Tablet?

Does Alkepin 10mg Tablet cause sleepiness?

Is Alkepin 10mg Tablet addictive?

Does Alkepin 10mg Tablet affect blood sugar level?

Can I drink alcohol while taking Alkepin 10mg Tablet?

I am experiencing a change in my taste after the start of the treatment with Alkepin 10mg Tablet. Any tips to reduce it?

Can I take fluoxetine with Alkepin 10mg Tablet?

Is Alkepin 10mg Tablet FDA approved?

Is Alkepin 10mg Tablet a narcotic, or controlled substance?

Is Alkepin 10mg Tablet addictive?

Can I take Xanax or Benadryl with Saphris?

Does Alkepin 10mg Tablet cause weight gain?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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