Adsunib 50 Capsule is a medicine used in the treatment of kidney cancer and gastrointestinal stromal tumor. It works by blocking specific enzymes that promote the growth of cancer cells. This way it shrinks the tumor and slows down its progression.

Adsunib 50 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Common side effects of this medicine include weakness, diarrhea, nausea, vomiting, taste change, and decreased appetite. The doctor may advise for regular monitoring of blood pressure and thyroid gland function while taking this medicine. It may decrease blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, if you are diabetic then it is important to check your blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or bleeding disorder. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Adsunib Capsule

Benefits of Adsunib Capsule

In Treatment of Kidney cancer

Adsunib 50 Capsule is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Treatment of Gastrointestinal stromal tumour

A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Adsunib 50 Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

show less

Side effects of Adsunib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Adsunib

Hand-foot syndrome
Bleeding disorder
Low blood platelets
Decreased appetite
Nausea
Vomiting
Weakness
Abdominal pain
Indigestion
High blood pressure
Diarrhea
Stomatitis (Inflammation of the mouth)
Taste change

How to use Adsunib Capsule

Take this medicine in the dose and duration as advised by your doctor. Adsunib 50 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Adsunib Capsule works

Adsunib 50 Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Adsunib 50 Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Adsunib 50 Capsule may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Adsunib 50 Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Adsunib 50 Capsule may cause side effects which could affect your ability to drive.
Adsunib 50 Capsule may cause dizziness during the treatment. Do not drive or operate machineries if you experience this while on treatment with the medicine.

Kidney

SAFE IF PRESCRIBED

Adsunib 50 Capsule is safe to use in patients with kidney disease. No dose adjustment of Adsunib 50 Capsule is recommended.

Liver

SAFE IF PRESCRIBED

Adsunib 50 Capsule is safe to use in patients with liver disease. No dose adjustment of Adsunib 50 Capsule is recommended.

What if you forget to take Adsunib Capsule?

If you miss a dose of Adsunib 50 Capsule, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Adsunib 50 Capsule

₹256.21/Capsule

Sutinat 50 Capsule

Natco Pharma Ltd

₹357.14/capsule

39% costlier

Tunib 50 Capsule

Panacea Biotec Ltd

₹443.82/capsule

73% costlier

Sutent 50mg Capsule

Pfizer Ltd

₹7146.14/capsule

2689% costlier

View all substitutes

Quick tips

Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
In case you need to undergo any surgical procedure, ensure to inform the doctor about your use of Adsunib 50 Capsule.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Monitoring of thyroid gland function is required while taking this medicine. Inform your doctor if you notice symptoms of weight gain, dry skin, and hair.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class

Indole and Pyrrole Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Patient concerns

From last two months i found a pimple type on inner side of my lower lil. There is no pain in i Is there any risk of cancer

Dr. Vijay Sharnangat

Medical Oncology and Hematology

No risk for tumour

Right lung tumour cancer in upper portion In jalgaon district which oncologist is best for lung cancer.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

Dr Nitin Chaudhari us best oncologist

She is admitted in hospital for last 2 wks due to Plural effusion,ascites & Distended illium & jejunum portion,she has tested with USG of abdomen,Beta HCG, and tumor marker test,but In case of tumor marker test CA 125 is extensively high,its 945 dr. refers for a gynaecologist,what to do now ?? Dr. also aware to the patient,that they can operate Utectomy or may be cutting down of ovary is there any chance of CANCER ?

Dr. Megha Tuli

Obstetrics and Gynaecology

CA125 high indicates a ovarian tumour, which may or mayn't be malignant. For that surgery followed by tissue histopath reports will help in absolute diagnosis. The intestinal and effusion and acitis is not due to the ovarian tumour.

FAQs

Q. How should I take Adsunib 50 Capsule?

You should take Adsunib 50 Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Adsunib 50 Capsule, as the chances of side effects may be more.

Q. Does Adsunib 50 Capsule have any effect on skin and hair?

During treatment with Adsunib 50 Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Adsunib 50 Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.

Q. What is the most important thing I need to know about Adsunib 50 Capsule?

Adsunib 50 Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Adsunib 50 Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.

Q. Are generics available for Adsunib 50 Capsule? How does Adsunib 50 Capsule work?

There are no generics available for Adsunib 50 Capsule. Adsunib 50 Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.

Q. Can Adsunib 50 Capsule be used in combination with other chemotherapy medicines?

There are no studies that support the use of Adsunib 50 Capsule with other chemotherapy medicines. For example, Adsunib 50 Capsule is used in Gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel, when imatinib (another anticancer medicine) no longer works or the patient cannot take imatinib.

Q. Does Adsunib 50 Capsule have any effect on blood sugar levels in diabetics?

Yes, Adsunib 50 Capsule may decrease your blood sugar levels. Therefore, if you are a diabetic, you need to be extra careful since your blood sugar levels may become so low that you may become unconscious. Keep a regular check on the blood sugar levels, based on which your dose of anti-diabetics may be changed.

Q. Can Adsunib 50 Capsule cause any change in blood pressure?

Generally, Adsunib 50 Capsule is known to cause an increase in blood pressure. Therefore, it is important that you keep a regular check on your blood pressure levels. Inform your doctor if you have severe headache, dizziness, lightheadedness or change in vision. Your doctor may prescribe a medicine to treat the increase blood pressure or may stop your treatment temporarily till your blood pressure returns to normal.

Show less

Related lab tests

Complete Blood Count

Top Medical Oncologists

Dr. Shyam Aggarwal

MBBS, MD

4.9 ★

Dr. Amit Agarwal

MBBS, MD, DM, Fellowship

4.7 ★

4.3 ★

4.2 ★

MBBS, MD, DM, Fellowship

5 ★

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1304.
Sunitinib malate [Prescribing Information]. New York, New York: Pfizer Inc.; 2021. [Accessed 25 Oct. 2023] (online) Available from:
Sunitinib malate. Sandwich, Kent: Pfizer Limited; 2006 [revised Feb. 2019]. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:

Marketer details

Name: Adley Formulations

Address: Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.