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Adsunib 12.5 Capsule

Prescription Required
Manufacturer/ Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Adsunib 12.5 Capsule is used in the treatment of kidney cancer and gastrointestinal stromal tumor.

Adsunib 12.5 Capsule can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, weakness and weight loss are some common side effects of this medicine. The doctor may advise for regular monitoring of blood pressure and thyroid gland function while taking this medicine.  It may decrease blood sugar levels. In fact, the levels can decrease to the extent that the patient may faint. So, if you are diabetic then it is important to check your blood sugar levels regularly. Additionally, you should also consult the doctor if the dose of anti-diabetic medicines needs to be adjusted. This medicine may affect wound healing time, so be careful while shaving, cutting fingernails or using sharp objects.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or bleeding disorder. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Benefits of Adsunib Capsule

In Kidney cancer

Adsunib 12.5 Capsule is used to treat kidney cancer and its associated symptoms such as blood in the urine, unexplained low back pain or weight loss, fatigue, loss of appetite, etc. It stops cancer growth and prevents multiplication of cancer cells. This restricts the advancement of cancer to other unaffected regions. You need to follow your doctor’s instructions very carefully to recover.

In Gastrointestinal stromal tumour

A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Adsunib 12.5 Capsule helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit.

Side effects of Adsunib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Adsunib

  • Nausea
  • Vomiting
  • Weakness
  • Rash
  • Abdominal pain
  • Indigestion
  • Discoloration of skin
  • Fatigue
  • Fever
  • Dry skin
  • High blood pressure
  • Diarrhea
  • Constipation
  • Painful blisters on hands and feet
  • Stomatitis (Inflammation of the mouth)
  • Hair discoloration
  • Pain in extremities
  • Back pain
  • Headache
  • Joint pain
  • Weight loss
  • Cough
  • Taste change
  • Breathlessness

How to use Adsunib Capsule

Take this medicine in the dose and duration as advised by your doctor. Adsunib 12.5 Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Adsunib Capsule works

Adsunib 12.5 Capsule is an anti-cancer medication. It works by binding and blocking certain cell surface protein (tyrosine kinase) responsible for the propagation of cancer growth. It also restricts the growth of new blood vessels within the tumor. This is how it prevents the proliferation of malignant cancers.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Adsunib 12.5 Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Adsunib 12.5 Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Adsunib 12.5 Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Adsunib 12.5 Capsule may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Adsunib 12.5 Capsule is safe to use in patients with kidney disease. No dose adjustment of Adsunib 12.5 Capsule is recommended.
Liver
CAUTION
Adsunib 12.5 Capsule should be used with caution in patients with severe liver disease. Dose adjustment of Adsunib 12.5 Capsule may be needed. Please consult your doctor.
Limited information is available on the use of Adsunib 12.5 Capsule in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Adsunib Capsule?

If you miss a dose of Adsunib 12.5 Capsule, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Adsunib 12.5 Capsule
₹60.79/Capsule
Sunixar 12.5 Capsule
Sun Pharmaceutical Industries Ltd
₹50.71/capsule
17% cheaper
Sutib 12.5 Capsule
Glenmark Pharmaceuticals Ltd
₹60.43/capsule
1% cheaper
Sunicine Capsule
Arechar Healthcare
₹62.25/capsule
2% costlier
₹63.71/capsule
5% costlier
Rcnet 12.5 Capsule
BDR Pharmaceuticals Internationals Pvt
₹66.43/capsule
9% costlier

Quick tips

  • Adsunib 12.5 Capsule is used for the treatment of thyroid cancer.
  • Take it with or without food, preferably at the same time each day.
  • Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
  • It may affect wound healing time. Be careful while shaving, cutting fingernails or toenails, or using sharp objects.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
  • Monitoring of thyroid gland function is required while taking this medicine.  Inform your doctor if you notice symptoms of weight gain, dry skin, and hair.
  • It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
  • Inform your doctor about the consumption of Adsunib 12.5 Capsule before going for surgical procedure.
  • Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Fact Box

Chemical Class
Indole and Pyrrole Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine kinase inhibitors

Patient concerns

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No risk for tumour
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FAQs

Q. How should I take Adsunib 12.5 Capsule?

You should take Adsunib 12.5 Capsule exactly as directed by your doctor. It should be started by doctors who have experience in administering cancer medicines. Take it once a day with or without food. Do not drink grapefruit juice or eat grapefruit during your treatment with Adsunib 12.5 Capsule, as the chances of side effects may be more.

Q. Does Adsunib 12.5 Capsule have any effect on skin and hair?

During treatment with Adsunib 12.5 Capsule, your skin may get lighter and there may be hair loss. Also, patient may experience dryness, thickness or cracking of the skin, blisters, or rashes on the palms and soles. But, these side effects are reversible and go away once the medicine is stopped. Adsunib 12.5 Capsule may also cause serious skin reactions such as severe rash or rapidly spreading skin ulceration which could be fatal. Therefore, inform your doctor immediately if symptoms of infection occur around a skin injury. Let your doctor know if you have fever, pain, redness, swelling, or drainage of pus or blood.

Q. What is the most important thing I need to know about Adsunib 12.5 Capsule?

Adsunib 12.5 Capsule can cause serious side effects such as severe liver problems that can lead to death. Therefore, tell your doctor right away if you experience itching, yellow eyes or skin, dark urine or pain or discomfort in the right upper stomach area. Your doctor will get blood tests done to check your liver function before and during treatment with Adsunib 12.5 Capsule. In case you develop liver problems, your doctor may stop the medicine temporarily or permanently.

Q. Are generics available for Adsunib 12.5 Capsule? How does Adsunib 12.5 Capsule work?

There are no generics available for Adsunib 12.5 Capsule. Adsunib 12.5 Capsule blocks an enzyme which promotes the growth and spread of cancer cells. This enzyme is called protein kinase and is present on the surface of cancer cells. Blocking this enzyme stops the spread of cancer. Examples of other protein kinase inhibitors are erlotinib, gefitinib, lapatinib, vemurafenib and dasatinib.

Q. Can Adsunib 12.5 Capsule be used in combination with other chemotherapy medicines?

There are no studies that support the use of Adsunib 12.5 Capsule with other chemotherapy medicines. For example, Adsunib 12.5 Capsule is used in Gastrointestinal stromal tumour (GIST), a type of cancer of the stomach and bowel, when imatinib (another anticancer medicine) no longer works or the patient cannot take imatinib.

Q. Does Adsunib 12.5 Capsule have any effect on blood sugar levels in diabetics?

Yes, Adsunib 12.5 Capsule may decrease your blood sugar levels. Therefore, if you are a diabetic, you need to be extra careful since your blood sugar levels may become so low that you may become unconscious. Keep a regular check on the blood sugar levels, based on which your dose of anti-diabetics may be changed.

Q. Can Adsunib 12.5 Capsule cause any change in blood pressure?

Generally, Adsunib 12.5 Capsule is known to cause an increase in blood pressure. Therefore, it is important that you keep a regular check on your blood pressure levels. Inform your doctor if you have severe headache, dizziness, lightheadedness or change in vision. Your doctor may prescribe a medicine to treat the increase blood pressure or may stop your treatment temporarily till your blood pressure returns to normal.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1740.
  2. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 955.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1304.
  4. Sunitinib malate. New York, New York: Pfizer Inc.; 2006 [revised May 2011]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  5. Drugs.com. Sunitinib Pregnancy and Breastfeeding Warnings. [Accessed 27 Mar. 2019] (online) Available from:External Link
  6. Sunitinib malate. Sandwich, Kent: Pfizer Limited; 2006 [revised Feb. 2019]. [Accessed 27 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Adley Formulation, SCO- 42, Sector 12, Panchkula-134112, Haryana, India
Country of origin: India

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