Actigesic 75mg Injection

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Actigesic 75mg Injection is a pain-relieving medicine. It is used to treat various types of pain, swelling, stiffness, and joint pain in conditions like rheumatoid arthritis, osteoarthritis, and acute musculoskeletal injuries. It is given in cases where oral administration is not possible.

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Actigesic 75mg Injection

ampoule of 1 ml Injection

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Same composition

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ampoule of 1 ml Injection

Diclofenac (75mg)

by Cipla Ltd

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General Information

Contains

Diclofenac (75mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Actigesic 75mg Injection is generally administered by a doctor or a nurse. Do not self-administer this medicine at home. Inform your doctor if you have any history of heart disease or stroke. Consult your doctor in case any injection site reactions like pain, swelling, or redness are observed.

The most common side effects of this medicine include nausea, vomiting, headache, and injection site reactions. Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.

Uses of Actigesic Injection

Pain relief

Benefits of Actigesic Injection

Pain relief
Actigesic 75mg Injection belongs to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). It is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.

Take it as it is prescribed to get the most benefit. Do not take more or longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Actigesic Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Actigesic

Diarrhea
Flatulence
Vomiting
Headache
Injection site reactions (pain, swelling, redness)
Dizziness
Nausea
Constipation
Insomnia (difficulty in sleeping)
Abdominal pain
Dyspepsia
Gastrointestinal bleeding
Gastrointestinal ulcer
Rash
Application site irritation
Injection site pain

How to use Actigesic Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Actigesic Injection works

Actigesic 75mg Injection is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).

All substitutes for Actigesic 75mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Actigesic 75mg Injection to relieve pain and inflammation.
Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
It may cause dizziness, drowsiness, or visual disturbances. Use caution while driving or doing anything that requires concentration.
Avoid consuming alcohol while taking Actigesic 75mg Injection as it can cause excessive drowsiness and increase your risk of stomach problems.
Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Actigesic 75mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Actigesic 75mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Actigesic 75mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Actigesic 75mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Actigesic 75mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Actigesic 75mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Actigesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Fondaparinux (Injection Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately.

Severe

Heparin (Injection Route)

Do not consume Diclofenac with Heparin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Diclofenac may increase the effect of Heparin.

Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

How should Actigesic 75mg Injection be administered?

Actigesic 75mg Injection should only be given by a healthcare professional. It can be given deep into the muscle (intramuscularly), preferably in the buttock, under the skin (subcutaneously), or directly into a vein (intravenously) as a bolus and not as an infusion. The dose should not exceed the prescribed quantity and injection should not be given for more than 2 days.

What is the most important information I need to know about Actigesic 75mg Injection?

It is important to know that Actigesic 75mg Injection may increase your chance of having a heart attack or stroke. The risk is higher if you take higher doses and have used the medicine for a long time. Additionally, Actigesic 75mg Injection may cause ulcers, bleeding, or holes in your stomach and intestine. If you experience any such problems, consult your doctor immediately.

Is Actigesic 75mg Injection a good painkiller?

Actigesic 75mg Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains, and other injuries. It is also helpful in various types of arthritis, gout, pain, and inflammation following surgery.

Can Actigesic 75mg Injection hurt your kidneys?

Long-term use and high doses of Actigesic 75mg Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include dehydrated people, individuals with heart failure, impaired kidney function, hypertension, and the elderly. Hence, for such patients kidney function monitoring is recommended.

Is Actigesic 75mg Injection a good painkiller?

Actigesic 75mg Injection is effective in relieving pain and inflammation. It is used for various sorts of pain such as sprains, strains and other injuries. It is also helpful in various types of arthritis, gout, pain and inflammation following surgery.

Is Actigesic 75mg Injection a narcotic?

No, Actigesic 75mg Injection is not a narcotic. It belongs to non-steroidal anti-inflammatory drugs (NSAIDs) group of medicines.

Does Actigesic 75mg Injection get you high?

No, Actigesic 75mg Injection does not get you high. It does not have an abuse potential (drug-seeking behavior) and does not cause physical or psychological dependence. However, if you do not feel well, consult your doctor.

Can Actigesic 75mg Injection damage your kidneys?

Long-term use and high doses of Actigesic 75mg Injection may cause renal problems such as protein or blood in urine and painful urination. Patients who are at maximum risk of developing kidney problems include people who are dehydrated, have heart failure, impaired kidney function, hypertension, elderly, who are on medicines which cause excess urination (diuretics), or medicines which have significant impact on kidney function. Hence, for such patients kidney function monitoring is recommended.

Does Actigesic 75mg Injection make you drowsy?

Actigesic 75mg Injection can cause drowsiness and also dizziness, fatigue (tiredness) and visual disturbances. However, it is not very common and may not affect everyone. If you experience these symptoms avoid driving or operating heavy machinery.

What is the most important information I need to know about Actigesic 75mg Injection?

It is important to know that Actigesic 75mg Injection may increase your chance of having a heart attack or stroke. The risk is more if you take higher doses and have been using the medicine for a longer time. Also, taking Actigesic 75mg Injection may cause ulcers, bleeding, or holes in your stomach and intestine. These problems may happen without warning symptoms at any time during treatment and may even cause death. Therefore, if you encounter any such problems, consult your doctor immediately.

Can Actigesic 75mg Injection be taken during pregnancy?

You should not take Actigesic 75mg Injection during the last 3 months of pregnancy as it may cause harmful effects on your baby. Use of Actigesic 75mg Injection can also lead to reduced labor (premature delivery). Hence, it is advised to avoid using Actigesic 75mg Injection during the first 6 months of pregnancy also. In some cases, Actigesic 75mg Injection may be prescribed in pregnant women only if the benefits outweigh the risks involved with its use in pregnant women. If not sure, consult your doctor regarding its use.

Fact Box

Chemical Class

Dichlorobenzenes

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)

References

Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 626.
Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 986-87.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 295-97.
Diclofenac. Dublin 2, Republic of Ireland: Flynn Pharma Ltd.; 2017. [Accessed 02 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
Diclofenac [Prescribing Information]. Lake Forest, IL: Hospira, Inc.; 2014. [Accessed 06 Apr. 2024] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Actigesic 75mg Injection

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Actigesic Injection

Benefits of Actigesic Injection

Side effects of Actigesic Injection

How to use Actigesic Injection

How Actigesic Injection works

All substitutes for Actigesic 75mg Injection

Vovedic Injection

Dynapar AQ Injection 1ml

Diclotal AQ Injection

Voveran AQ Injection

Dilona Aqua Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Fondaparinux (Injection Route)

Heparin (Injection Route)

Tacrolimus (Oral Route)

Methotrexate (Injection Route)

Methotrexate (Injection Route)

Frequently asked questions

How should Actigesic 75mg Injection be administered?

What is the most important information I need to know about Actigesic 75mg Injection?

Is Actigesic 75mg Injection a good painkiller?

Can Actigesic 75mg Injection hurt your kidneys?

Is Actigesic 75mg Injection a good painkiller?

Is Actigesic 75mg Injection a narcotic?

Does Actigesic 75mg Injection get you high?

Can Actigesic 75mg Injection damage your kidneys?

Does Actigesic 75mg Injection make you drowsy?

What is the most important information I need to know about Actigesic 75mg Injection?

Can Actigesic 75mg Injection be taken during pregnancy?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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