Abirasym 500 Tablet
Prescription Required
Product introduction
Abirasym 500 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
Abirasym 500 Tablet should not be taken on an empty stomach. Taking it with food may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
The most common side effects of this medicine include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, and fatigue. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, yellowing of skin, loss of appetite, shortness of breath, dark urine and nausea can happen, which indicate some liver problem. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.
Before taking it, tell your doctor if have high blood pressure, heart problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.
Uses of Abirasym Tablet
Benefits of Abirasym Tablet
In Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Abirasym 500 Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Side effects of Abirasym Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Abirasym
- Edema (swelling)
- Vomiting
- Decreased potassium level in blood
- Fatigue
- Anemia (low number of red blood cells)
- Urinary tract infection
- Diarrhea
- High blood pressure
- Cough
- Joint swelling
How to use Abirasym Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Abirasym 500 Tablet is to be taken empty stomach.
How Abirasym Tablet works
Abirasym 500 Tablet is an anticancer medication. It works by preventing androgen (male hormone) production in man. This is done by inhibiting an enzyme (CYP17) that is responsible for the production of androgen. This is how it slows down the growth of prostate cancer.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Abirasym 500 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Abirasym 500 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Abirasym 500 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Abirasym 500 Tablet does not usually affect your ability to drive.
Kidney
CAUTION
Abirasym 500 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Abirasym 500 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Abirasym 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Abirasym 500 Tablet may be needed. Please consult your doctor.
What if you forget to take Abirasym Tablet?
If you miss a dose of Abirasym 500 Tablet, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Abirasym 500 Tablet
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Quick tips
- Abirasym 500 Tablet treats prostate cancer that has spread to other parts of the body.
- It is usually taken with another medicine called prednisolone to reduce unwanted side effects.
- It must be taken on an empty stomach. Don't eat any food for at least 2 hours before or 1 hour after your dose.
- Always use effective birth control measures to prevent pregnancy while taking this medicine.
- Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.
Fact Box
Chemical Class
Androstene Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Anticancer-others
Interaction with drugs
Taking Abirasym with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Concurrent use may cause serious disturbance in heart rhythm.
Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart
Patient concerns
FAQs
Can Abirasym 500 Tablet cure prostate cancer?
Abirasym 500 Tablet does not cure cancer but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with Abirasym 500 Tablet then the frequency of fractures is relatively less. Similarly, the increase in pain is less common with Abirasym 500 Tablet.
Is Abirasym 500 Tablet a chemotherapy drug?
Abirasym 500 Tablet is a hormonal treatment not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. Abirasym 500 Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.
Why do I need to take prednisolone with Abirasym 500 Tablet?
Your doctor will always prescribe prednisolone with Abirasym 500 Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to Abirasym 500 Tablet.
Does Abirasym 500 Tablet affect liver?
Abirasym 500 Tablet can cause severe liver problems. In very rare cases, Abirasym 500 Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.
How frequently should the liver investigations be done?
Liver enzymes should be measured prior to starting the treatment, every two weeks for the first three months into the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with Abirasym 500 Tablet.
How to take Abirasym 500 Tablet?
Abirasym 500 Tablet should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of Abirasym 500 Tablet in your blood which can be harmful. Remember not to crush or chew the tablet.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 4-5.
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- Abiraterone Acetate. Patheon Inc.: Mississauga, Canada; 2011 [revised May 2016]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
- Abiraterone acetate [Prescribing Information]. Toronto, Canada: Patheon Inc.; 2011. [Accessed 20 Feb. 2024] (online) Available from:
- CiplaMed. Abiraterone Acetate [Prescribing Information]. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Symbion Lifescience
Address: 430, Sidhharth Complex, NH 8, Vadodara
Country of origin: India
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