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ZELgor 500mg Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 23 Jan 2026 | 10:15 AM (IST)
ZELgor 500mg Tablet is used in the treatment of cancer of the prostate gland. It may also be used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.
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ZELgor 500mg Tablet is currently sold out
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Xbira 500 Tablet
₹14435₹20625
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ZELgor 500mg Tablet
ZELgor 500mg Tablet
bottle of 60 tablets
₹11210
₹12187.5
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Same composition
Xbira 500 Tablet
Xbira 500 Tablet
bottle of 60 tablets
by Cipla Ltd
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₹14435
₹240.58 per tablet

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The content is shown in English
ZELgor 500mg Tablet image
ZELgor 500mg Tablet image
ZELgor 500mg Tablet image
ZELgor 500mg Tablet image

Product introduction

ZELgor 500mg Tablet should be taken on an empty stomach, either one hour before or at least two hours after a meal. Taking it with food may increase the blood levels of ZELgor 500mg Tablet, which may cause side effects. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits, but do not stop taking it unless your doctor tells you to.


The most common side effects of ZELgor 500mg Tablet include vomiting, decreased potassium level in blood, edema (swelling), decreased white blood cell count, and fatigue. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Other than this, the yellowing of the skin, loss of appetite, shortness of breath, dark urine, and nausea can happen, which indicate some liver problems. Your doctor might check you for liver function, blood pressure, and the level of potassium in your blood.


Before taking ZELgor 500mg Tablet, tell your doctor if you have high blood pressure, heart problems, liver or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medication, so let your doctor know about all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked to undergo regular monitoring of your blood glucose level while on treatment.

Uses of ZELgor Tablet

Benefits of ZELgor Tablet

Prostate cancer
Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. ZELgor 500mg Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of ZELgor Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of ZELgor
  • Edema (swelling)
  • Vomiting
  • Decreased potassium level in blood
  • Fatigue
  • Anemia (low number of red blood cells)
  • Urinary tract infection
  • Diarrhea
  • High blood pressure
  • Cough
  • Joint swelling
  • Nausea
  • Hot flashes
  • Headache
  • Increased glucose level in blood

How to use ZELgor Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. ZELgor 500mg Tablet is to be taken on an empty stomach.

How ZELgor Tablet works

ZELgor 500mg Tablet works by blocking an enzyme called CYP17, which is involved in the production of androgens (male hormones like testosterone). Since many prostate cancers rely on these hormones to grow, reducing their levels helps slow down or stop the cancer's progression. Essentially, ZELgor 500mg Tablet cuts off the fuel supply that the cancer needs to thrive.

Quick tips

  • ZELgor 500mg Tablet is usually taken with another medicine called prednisolone to reduce unwanted side effects.
  • It should be taken on an empty stomach, either one hour before or at least two hours after a meal.
  • Always use effective birth control measures to prevent pregnancy while taking this medicine.
  • Your doctor may regularly monitor your liver function, blood pressure, and the level of potassium in your blood while you are having treatment with this medicine.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with ZELgor 500mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
ZELgor 500mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
ZELgor 500mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
ZELgor 500mg Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
ZELgor 500mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
ZELgor 500mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking ZELgor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Disopyramide (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

ZELgor 500mg Tablet should be taken on an empty stomach with water 1 hour before eating or at least 2 hours after eating. Taking it with food may cause increased and variable levels of ZELgor 500mg Tablet in your blood, which can be harmful. Remember not to crush or chew it.
ZELgor 500mg Tablet does not cure cancer, but helps in prolonging and improving the life of the patient. Moreover, when prostate cancer is treated with ZELgor 500mg Tablet, then the frequency of fractures is relatively lower. Similarly, the increase in pain is less common with ZELgor 500mg Tablet.
ZELgor 500mg Tablet is a hormonal treatment, not a chemotherapy drug. It is used to treat prostate cancer in adult men that has spread to other parts of the body. ZELgor 500mg Tablet stops your body from making testosterone. This can slow down the growth of prostate cancer.
Your doctor will always prescribe prednisolone with ZELgor 500mg Tablet. Taking these two medicines together lowers the risk of getting high blood pressure, fluid retention (having too much water in your body), or having reduced levels of potassium in your blood, which can occur due to ZELgor 500mg Tablet.
ZELgor 500mg Tablet can cause severe liver problems. In very rare cases, ZELgor 500mg Tablet may even cause failure of the liver to function (called acute liver failure), which can even lead to death. Tell your doctor if you experience yellowing of the skin or eyes, darkening of the urine, or severe nausea or vomiting, as these could be signs or symptoms of liver problems.
Liver enzymes should be measured before starting the treatment, every two weeks for the first three months of the treatment, and monthly thereafter. If you develop clinical symptoms or signs suggestive of liver toxicity, liver enzymes should be measured immediately. If the liver enzyme levels are increased beyond certain levels, your doctor may temporarily discontinue the treatment with ZELgor 500mg Tablet.

Fact Box

Chemical Class

Androgen derivative

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents
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100% genuine products
Safe & secure payments
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No contact delivery
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Fully sanitized facilities
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User feedback

Prostate cancer
100%
Excellent
33%
Poor
33%
Average
33%
Headache
33%
Vomiting
33%
Joint pain
33%
Empty stomach
100%
Expensive
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India
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