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Ryze 4mg Nicotine Gum Royal Paan

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 12 Jan 2026 | 07:06 PM (IST)
Ryze 4mg Nicotine Gum Royal Paan is a medicine used to quit smoking by reducing the craving for a cigarette and the irritable feeling that occurs when you stop smoking. It works by mimicking the effect of nicotine by binding to the nicotine receptors in the brain.
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Ryze 4mg Nicotine Gum Royal Paan is currently sold out
Same composition alternative:
Nicochew 4mg Gum
₹48.4₹53.61
43% cheaper alternative available from Cipla
Sold out
Ryze 4mg Nicotine Gum Royal Paan
Ryze 4mg Nicotine Gum Royal Paan
box of 9 gum
₹76.2
₹84.38
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Same composition
Nicochew 4mg Gum
Nicochew 4mg Gum
packet of 10 gum
Nicotine (4mg)
by Cipla Ltd
Get by Wed, 15 Apr
₹48.4
₹4.11 per unit

₹41.1

order for
₹1200

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General Information

Contains

Nicotine (4mg)

Marketer

Vectura Fertin Pharma Private Limited

Storage

Store below 25°C
The content is shown in English
Ryze 4mg Nicotine Gum Royal Paan image
Ryze 4mg Nicotine Gum Royal Paan image

Product introduction

Ryze 4mg Nicotine Gum Royal Paan can be used to help you stop smoking completely or cut down the amount you smoke. Stopping smoking is hard, and you need to be ready and committed. But quitting is one of the most important things you can do to improve your health and live longer. This medicine should be taken as advised by the doctor, as it can be habit-forming. In case you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment. However, before taking this medicine, it is better to inform your doctor if you are suffering from any heart, liver, or kidney disease. You must not smoke while using this medicine, as it can result in dangerous effects.


Many people use more than one type of nicotine replacement therapy (NRT) to improve their chances, such as nose or mouth sprays, which also contain nicotine. You are more likely to be successful if you also have counselling, join a support group, and make some behaviour changes, such as avoiding situations you associate with smoking.


Some of the common side effects include nausea, vomiting, sore throat, and mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you feel better. It may cause headaches, so it is better to take plenty of fluids the whole day, but inform your doctor if it does not go away. These effects are often mild and will wear off with time. If you are pregnant or breastfeeding, you must consult a doctor before taking this medicine.

Uses of Ryze Gum

  • Quitting smoking

Benefits of Ryze Gum

Quitting smoking
Tobacco contains the substance nicotine which is extremely addictive. Ryze 4mg Nicotine Gum Royal Paan is a form of nicotine replacement therapy (NRT). It contains nicotine but not the other toxic chemicals in tobacco smoke such as tar and carbon monoxide. It may be used to help you quit smoking and reduce the unpleasant withdrawal effects and cravings that often occur when you stop smoking. This medicine has worked very well for many years to help people stop smoking and is even more effective if you have other support such as counseling. This treatment may take several weeks to work so you need to continue until you have been successful. Quitting smoking is extremely hard and requires you to change your behaviors but it has a huge range of health benefits and dramatically improves your quality of life.

Side effects of Ryze Gum

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Ryze
  • Vomiting
  • Hiccup
  • Dryness in mouth
  • Flatulence
  • Stomatitis (Inflammation of the mouth)
  • Pharyngolaryngeal pain
  • Abdominal pain
  • Diarrhea
  • Constipation
  • Cough
  • Nausea
  • Insomnia (difficulty in sleeping)

How Ryze Gum works

Nicotine works by binding to nicotine receptors in the brain during abstinence from smoking. This helps to reduce craving and withdrawal symptoms.

All substitutes for Ryze 4mg Nicotine Gum Royal Paan

For information purposes only. Consult a doctor before taking any medicine.

Nicochew 4mg Gum

by Cipla Ltd
₹53.61/gum
36% cheaper
<h3 class=bodySemiBold>Nicochew 4mg Gum</h3>

Quick tips

  • Ryze 4mg Nicotine Gum Royal Paan helps you to quit smoking by reducing the craving for a cigarette and the irritable feeling that occurs when you stop smoking.
  • In addition, counselling should be done to increase the chances of quitting smoking successfully.
  • Quitting smoking can lower your chances of having lung disease, heart disease, or getting certain types of cancer that are related to smoking.
  • Do not smoke while using Ryze 4mg Nicotine Gum Royal Paan as it can cause nicotine to build up to dangerous levels.
  • Inform your doctor if you develop a headache, nausea, or other digestive problems that do not go away.
  • Talk to your doctor if you are having trouble stopping Ryze 4mg Nicotine Gum Royal Paan, as it can be addictive.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Ryze 4mg Nicotine Gum Royal Paan. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Ryze 4mg Nicotine Gum Royal Paan is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

UNSAFE
Ryze 4mg Nicotine Gum Royal Paan is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Ryze 4mg Nicotine Gum Royal Paan does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Ryze 4mg Nicotine Gum Royal Paan should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Ryze 4mg Nicotine Gum Royal Paan should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Ryze with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Memantine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Bupropion (Oral Route)

If concurrent use is essential, your doctor may monitor your blood pressure closely. Nicotine may reduce the efficacy of Bupropion.
Mild

Aminophylline (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Mild

Theophylline (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Nicotine may reduce blood levels of the active form of Theophylline.
Mild

Theophylline (Injection Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Nicotine may reduce blood levels of the active form of Theophylline.

Frequently asked questions

Ryze 4mg Nicotine Gum Royal Paan is used as a nicotine replacement therapy to help people quit smoking. It reduces withdrawal symptoms and cigarette cravings, making it easier to stop smoking.
Ryze 4mg Nicotine Gum Royal Paan should not be used by non-smokers, children under 12 years of age, or anyone allergic to nicotine or any of the ingredients in the medicine. It is intended only for individuals who are actively trying to quit smoking.
Yes. Using too much Ryze 4mg Nicotine Gum Royal Paan or combining it with smoking can lead to a nicotine overdose. Symptoms may include nausea, vomiting, dizziness, sweating, stomach pain, irregular heartbeat, and, in severe cases, breathing problems or seizures. Seek medical help immediately if these occur.
Individuals with a recent heart attack, severe irregular heartbeat, uncontrolled high blood pressure, or unstable chest pain should not use Ryze 4mg Nicotine Gum Royal Paan unless prescribed by a doctor and closely monitored, as nicotine may place additional stress on the heart.
In rare cases, Ryze 4mg Nicotine Gum Royal Paan may increase the risk of seizures, especially in individuals with a history of epilepsy or those taking anti-seizure medications. If you experience seizures while using Ryze 4mg Nicotine Gum Royal Paan, stop treatment and seek medical care immediately.
Ryze 4mg Nicotine Gum Royal Paan may worsen conditions such as stomach ulcers, acid reflux, or esophagitis. If you have any of these conditions, use Ryze 4mg Nicotine Gum Royal Paan only after consulting your doctor.
Some people may become dependent on Ryze 4mg Nicotine Gum Royal Paan, but this is rare and generally less harmful than smoking. With proper use, the goal is to reduce the dose gradually until you no longer need nicotine.

Fact Box

Chemical Class

Pyrrolidinylpyridines

Habit Forming

No

Therapeutic Class

NEURO CNS

Action Class

Cholinomimetic Alkaloids

References

  1. Hibbs RE, Zambon AC. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 270-72.
  2. Lüscher C. Drugs of Abuse. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw-Hill Education Private Limited; 2009. pp. 561-62.
  3. Nicotine bitartrate dihydrate [EMC SmPC]. Brentford, Middlesex: GlaxoSmithKline Consumer Healthcare; 2016. [Accessed 23 Jan. 2019] (online) Available from:
  4. Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Nicotine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
  5. Nicotine [EMC SmPC]. Maidenhead, Berks: McNeil Products Ltd.; 2018. [Accessed 25 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Vectura Fertin Pharma Private Limited
Address: L-10 & L-11, Cuncolim Industrial Estate, Cuncolim, Salcette, South Goa 403 703.

Vendor Details

Country of origin: India

Lab tests offered by us

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