Provera 10mg Tablet

Written By Dr. Mayank, Pharm.D

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 13 Oct 2025 | 04:21 PM (IST)

Provera 10mg Tablet is similar to the progesterone hormone naturally produced by the body. It helps regulate abnormal uterine bleeding, induces withdrawal bleeding in cases of amenorrhea (the absence of menstrual periods), and may also be used to treat endometriosis.

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₹51.2 MRP ₹56.7510% off

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Provera 10mg Tablet

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Medroxyprogesterone acetate (10mg)

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General Information

Contains

Medroxyprogesterone acetate (10mg)

Marketer

Pfizer Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Provera 10mg Tablet should be taken as your doctor's advice. Your doctor will decide how much you need to take and for how much time. You may take it with or without food, but better to take it at a fixed time. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include headache, abdominal pain, breast pain, nausea and vomiting, hair loss, and vaginal infection. If any of these bother you, let your doctor know. There may be ways of reducing or preventing them. It may also cause irregular periods, bleeding, or spotting in between menstrual periods. Let your doctor know if this occurs frequently.

Before taking this medicine, you must let your doctor know if you have had any problems like bleeding or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Pregnant and breastfeeding women should not take this medicine. Do not take Provera 10mg Tablet if you currently have or have had cancer.

Uses of Provera Tablet

Benefits of Provera Tablet

Treatment of Abnormal uterine bleeding
Provera 10mg Tablet is a synthetic progestin that replicates the effect of a natural female hormone called progesterone. It slows the growth of the lining of the womb before menstruation, which reduces the bleeding during menstruation. If heavy periods become such a problem that they interfere with your everyday life, then try taking things a little easier on those days. Some women find that relaxation techniques or yoga help them feel more relaxed and reduce stress. Getting a lot of exercise can also help.

Treatment of Amenorrhea
Provera 10mg Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. You should use the medicine as prescribed for it to be effective. Avoid any stress and follow your doctor’s instructions carefully. Improving weight and nutrition may be recommended in females with eating disorders or malnutrition to get the maximum benefit from Provera 10mg Tablet.

Treatment of Endometriosis
Provera 10mg Tablet contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. You should use the medicine as prescribed for it to be effective. Avoid any stress and follow your doctor’s instructions carefully. Improving weight and nutrition may be recommended in females with eating disorders or malnutrition to get the maximum benefit from Provera 10mg Tablet.

Side effects of Provera Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Provera

Headache
Abdominal pain
Breast pain
Irregular vaginal bleeding
Nausea
Vomiting
Hair loss
Edema (swelling)
Vaginal yeast infection

How to use Provera Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Provera 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Provera Tablet works

Provera 10mg Tablet is a progestin (female hormone). It works by replacing the natural progesterone hormone that the body is unable to make. This treats painful, irregular, or absent menstrual periods. It also prevents an overgrowth of the lining of the uterus in menopausal women taking estrogen (another female hormone).

All substitutes for Provera 10mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Provera 10mg Tablet may cause bleeding or spotting in between menstrual periods. Let your doctor know if this occurs frequently.
Stop taking Provera 10mg Tablet and inform your doctor immediately if you get severe headaches, stabbing pains, or swelling in one leg; pain in breathing; sudden changes in your vision or hearing; or yellowing of your skin or whites of your eyes.
Use a non-hormonal method of contraception, such as condoms, to prevent pregnancy while you are taking this medication.
Do not take Provera 10mg Tablet if you are pregnant or breastfeeding, have unusual vaginal bleeding, or have a history of blood clots, stroke, heart attack, liver problems, or bleeding problems.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Provera 10mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Provera 10mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Provera 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Provera 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CAUTION

Provera 10mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Provera 10mg Tablet may be needed. Please consult your doctor.

Liver

UNSAFE

Provera 10mg Tablet is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

Interaction with drugs

Taking Provera with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Letrozole (Oral Route)

Do not consume Letrozole with Medroxyprogesterone acetate if you have or had breast cancer. If essential, consult your doctor.

Severe

Mycophenolate mofetil (Oral Route)

Effective contraception must be used before, during, and for at least 6 weeks after stopping Mycophenolate mofetil. It is recommended to consult your doctor. Mycophenolate mofetil may reduce the efficacy of Medroxyprogesterone acetate.

Severe

Lorlatinib (Oral Route)

Do not consume Lorlatinib with Medroxyprogesterone acetate. Lorlatinib may reduce blood levels of Medroxyprogesterone acetate.

Moderate

Ursodeoxycholic Acid (Oral Route)

Careful consideration is advised when taking Ursodeoxycholic Acid with Medroxyprogesterone acetate. Your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Gliclazide (Oral Route)

Monitor your blood glucose levels regularly and talk to your doctor if you notice any unusual symptoms during the simultaneous use of these medicines.

Frequently asked questions

How does Provera 10mg Tablet work? What is it used for?

Provera 10mg Tablet works similarly to the progesterone hormone naturally produced by the body. It helps in regulating the periods, stopping irregular bleeding, and controlling the withdrawal bleeding in case of amenorrhea (unusual stopping of menstrual periods). It is also used to prevent endometrial hyperplasia (thickening of the lining of the uterus).

When and how to take Provera 10mg Tablet?

Take it strictly as advised by your doctor. The number of doses and the duration will depend on the medical problem you are being treated for. You can take it with or without food, preferably at the same time each day to ensure consistent levels of medicine in your body.<br>

What are the common side effects which I can experience while taking Provera 10mg Tablet?

The common side effects of Provera 10mg Tablet include headache, nausea (feeling sick), weight gain, breast pain, and unusual vaginal bleeding or spotting. Do not worry, most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.

Is Provera 10mg Tablet a contraceptive?

No, Provera 10mg Tablet is not a contraceptive. You should use an effective form of birth control to prevent pregnancy. If you think you have become pregnant while using the medicine, tell your doctor right away to avoid any harm to the baby.

Fact Box

Chemical Class

Gluco/Mineralocorticoids, Progestogins Derivatives

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Progestins (First generation)

Related lab tests

Beta Human Chorionic Gonodotropin, Free

Beta Human Chorionic Gonodotropin, Total

Progesterone

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 850-54.
MedIndia. Medroxyprogesterone. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Medroxyprogesterone Acetate [Patient Information Leaflet]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd. [Accessed 25 Jul. 2024] (online) Available from:
Medroxyprogesterone Acetate [Patient Information Leaflet]. NY, USA: Pfizer. 2007 [Accessed 19 Feb. 2025] (online) Available from:
Medroxyprogesterone Acetate [Patient Information Leaflet]. NW, USA: Pfizer. 2023 [Accessed 19 Feb. 2025] (online) Available from:

User feedback

Patients taking Provera 10mg Tablet

Once A Day

62%

Twice A Day

38%

What are you using Provera Tablet for?

Abnormal uterine bleeding

32%

Others

27%

Amenorrhea

26%

Contraception

15%

How much was the improvement?

Average

41%

Poor

32%

Excellent

28%

What were the side-effects while using Provera 10mg Tablet?

No Side Effect

67%

Headache

33%

How do you take Provera Tablet?

With food

80%

Empty stomach

10%

With or without food

10%

Please rate Provera 10mg Tablet on price

Not Expensive

63%

Average

23%

Expensive

13%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Provera 10mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Provera Tablet

Benefits of Provera Tablet

Side effects of Provera Tablet

How to use Provera Tablet

How Provera Tablet works

All substitutes for Provera 10mg Tablet

Gestoserv M 10mg Tablet

MEPRate 10mg Tablet

Deviry 10mg Tablet

Medrogest 10mg Tablet

Medrigest Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Letrozole (Oral Route)

Mycophenolate mofetil (Oral Route)

Lorlatinib (Oral Route)

Ursodeoxycholic Acid (Oral Route)

Gliclazide (Oral Route)

Frequently asked questions

How does Provera 10mg Tablet work? What is it used for?

When and how to take Provera 10mg Tablet?

What are the common side effects which I can experience while taking Provera 10mg Tablet?

Is Provera 10mg Tablet a contraceptive?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Beta Human Chorionic Gonodotropin, Free

Beta Human Chorionic Gonodotropin, Total

Progesterone

References

User feedback

Patients taking Provera 10mg Tablet

What are you using Provera Tablet for?

How much was the improvement?

What were the side-effects while using Provera 10mg Tablet?

How do you take Provera Tablet?

Please rate Provera 10mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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