




Minirin Melt 120mcg Tablet
Desmopressin (120mcg)
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Minirin Melt 120mcg Tablet is a medicine used in the treatment of diabetes insipidus and bed-wetting. It helps decrease the urge to urinate and helps resume a more normal lifestyle.
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
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General Information
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Product introduction
Minirin Melt 120mcg Tablet can be taken on an empty stomach or after food. Your doctor will decide the dose and how often you should take them. You should use it regularly to get the most benefit from the medicine. Do not stop using the medicine even if you feel better unless the doctor tells you so.
Some common side effects of this medicine include headache, stomach pain, and nausea. Let your doctor know if any of these side effects do not go away or get worse.
Before using this medicine, inform your doctor if you have any problems with your heart, liver, or kidneys. You should also tell your doctor all the other medicines you are taking. Your doctor may monitor your blood glucose regularly while on treatment with this medicine.
Uses of Minirin Tablet
Benefits of Minirin Tablet
Diabetes insipidus
Diabetes insipidus is a condition where the body loses too much water through frequent urination and excessive thirst, due to a hormone imbalance that affects how the kidneys manage fluids. Minirin Melt 120mcg Tablet helps the body retain water by acting like the natural hormone (vasopressin) that regulates urine production. This reduces urine output and helps maintain normal hydration levels, relieving constant thirst and frequent urination.
Diabetes insipidus is a condition where the body loses too much water through frequent urination and excessive thirst, due to a hormone imbalance that affects how the kidneys manage fluids. Minirin Melt 120mcg Tablet helps the body retain water by acting like the natural hormone (vasopressin) that regulates urine production. This reduces urine output and helps maintain normal hydration levels, relieving constant thirst and frequent urination.
Bed-wetting
Bed-wetting (nocturnal enuresis) is a common condition in children and sometimes adults, where involuntary urination happens during sleep, often due to the body producing more urine at night than the bladder can hold. Minirin Melt 120mcg Tablet helps by reducing nighttime urine production, allowing better bladder control and fewer disruptions during sleep. This improves sleep quality and boosts confidence and comfort, especially in children.
Bed-wetting (nocturnal enuresis) is a common condition in children and sometimes adults, where involuntary urination happens during sleep, often due to the body producing more urine at night than the bladder can hold. Minirin Melt 120mcg Tablet helps by reducing nighttime urine production, allowing better bladder control and fewer disruptions during sleep. This improves sleep quality and boosts confidence and comfort, especially in children.
Side effects of Minirin Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Minirin
- Headache
- Nausea
- Stomach pain
How to use Minirin Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Minirin Melt 120mcg Tablet may be taken with or without food.
How Minirin Tablet works
Minirin Melt 120mcg Tablet is a synthetic form of vasopressin (natural hormone that balances water). It works by causing reabsorption of water from the kidneys which controls excessive thirst and urination in diabetes insipidus. It also helps decrease night-time urine production and bedwetting in children. In addition to these, it reduces bleeding episodes by promoting the release of blood clotting factors.
Quick tips
- You have been prescribed Minirin Melt 120mcg Tablet for the treatment of diabetes insipidus and/or bed-wetting.
- Limit the amount of fluids you drink with this medication.
- Minirin Melt 120mcg Tablet can cause low sodium levels in your body. Get regular blood tests done to monitor the levels.
- Inform your doctor if you develop an infection, fever, diarrhea, or vomiting.
- Talk to your doctor if you have sudden weight gain or swelling in your arms and legs that does not go away.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Minirin Melt 120mcg Tablet. Please consult your doctor.

Pregnancy
SAFE IF PRESCRIBED
Minirin Melt 120mcg Tablet is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding
SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving
UNSAFE
Minirin Melt 120mcg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Minirin Melt 120mcg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Minirin Melt 120mcg Tablet in patients with liver disease.
Interaction with drugs
Taking Minirin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Tolvaptan (Oral Route)
Your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate
Aceclofenac (Oral Route)
Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate
Aceclofenac (Injection Route)
Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate
Aceclofenac (Oral Route)
Caution is advised when taking Desmopressin with Aceclofenac. Your doctor may monitor your sodium levels closely.
Moderate
Amitriptyline (Oral Route)
Caution is advised when taking Desmopressin with Amitriptyline. Your doctor may monitor your sodium levels closely.
Frequently asked questions
Follow all the instructions given by your doctor strictly. Restrict water intake after taking Minirin Melt 120mcg Tablet as drinking too much water can lead to fluid overload, which is a serious side effect. Try not to swallow water while swimming.
Minirin Melt 120mcg Tablet is usually prescribed for 3 months for bedwetting. After 3 months, your doctor will stop the medicine for a week to assess whether your child still needs Minirin Melt 120mcg Tablet or not.
No, Minirin Melt 120mcg Tablet does not cure bedwetting, but it helps control bedwetting. It works by replacing a hormone (vasopressin) that is normally produced in the body to help balance the amount of water and salt.
No, Minirin Melt 120mcg Tablet itself does not cause weight gain. Minirin Melt 120mcg Tablet may cause fluid overload which may in turn cause weight gain. Fluid overload is a serious side effect and you should immediately contact your doctor if you experience headache, nausea, vomiting, restlessness, tiredness, loss of appetite, sleepiness, confusion and muscle cramps.
No, Minirin Melt 120mcg Tablet is not a diuretic. It is a hormone which helps lower urine output in patients with diabetes insipidus and helps control bedwetting in children. It works by reducing the amount of urine produced by the kidneys, thereby reducing the frequency of urination.
Minirin Melt 120mcg Tablet should be taken with small quantity of water, juice or milk. If the child cannot swallow the whole tablet, crush or cut the tablet before giving it to the child. The sublingual tablets or ‘melts’ should be placed below the tongue and then melted tablet should be swallowed.
Fact Box
Chemical Class
Synthetic vasopressin analoguesues
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
Vasopressin Analogues
Related lab tests
References
- Reilly RF, Jackson EK. Regulation of Renal Function and Vascular Volume. In: Brunton LL, Chabner BA, Knollmann BC,12th ed. editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 712-14.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 375.
- Medlineplus. Desmopressin. [Accessed 04 Apr. 2019] (online) Available from:
- Desmopressin acetate. West Drayton, UK: Ferring Pharmaceuticals Ltd.; 2003 [revised Jun. 2011]. [Accessed 25 Jan. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 3 Apr. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Ferring Pharmaceuticals
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Address: K-28/1, ADDITIONAL MIDC , ANAND NAGAR , AMBERNATH - 421506 , INDIA
Vendor Details
Country of origin: Switzerland
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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