Ever Wondered Why Some People Are Taller Than Many Others?

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Rare and low frequency coding variants for the human height were found to significantly affect the human adult height, study suggests.

-Recent study, conducted in a population of 700,000 people, suggested that close to 83 DNA changes have a big impact on the height of people.

-The study was conducted by the Genetic Investigation of Anthropometric Traits (GIANT) across 300 research groups present globally

-The study was focused to identify low frequency and rarely occurring genetic variants that altered the proteins and therefore had stronger effects.

-The study suggested that in 27.4% of the cases, height is a inherited trait. The study also revealed new biological pathways that impacted the growth of the skeletal muscles. The protein STC2 (a rare height increasing allele) acts as a brake on the human height.

-Findings were published in Nature 

Source: Journal Nature 


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