Hepatitis B (Core) Total Antibody

The Hepatitis B Core Antibody (anti-HBc) is a type of antibody produced by the immune system in response to infection with the hepatitis B virus (HBV). These antibodies specifically target the core antigen of the virus, which is a protein found inside the viral particle.

The Hepatitis B (Core) Total Antibody detects the presence of hepatitis B core antibodies (anti-HBc) in the blood, which are present in the blood after exposure to the virus. It is useful for determining whether an individual has ever been infected with HBV, whether the infection is active, or if the individual has cleared the virus from their system. This test is valuable for evaluating individuals with a history of liver disease as well as those at risk of HBV infection, such as healthcare workers or individuals with multiple sexual partners. Detecting the presence of anti-HBc antibodies helps doctors differentiate between different phases of HBV infection and guide treatment decisions. Early diagnosis and intervention can help prevent complications such as cirrhosis or liver cancer, which are associated with chronic HBV infection.

A positive result generally indicates that the individual has had an exposure to hepatitis B at some point in their life, but it does not indicate whether the infection is currently active or resolved. To further clarify the current status of the infection, additional tests like the Hepatitis B surface antigen (HBsAg) or Hepatitis B DNA (viral load) tests can be recommended.

No special preparation is needed for this test. Eating and drinking can be done as per the daily routine. However, inform the doctor about all the medications or supplements or underlying liver disease, as these factors may influence the test results. 

Lab test results may vary across laboratories. Abnormal test results require an expert interpretation. Do not self-medicate. Always consult a doctor to understand the test results correctly.