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Endomysial - IgG antibody

Endomysial - IgG antibody

Also referred as
Endomysial Antibody IgA Test
EMA IgA Test
IgA-EMA Test
+1
Celiac Disease Test
For men & women
Earliest reports in
192 hours
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1 test
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The Endomysial - IgG antibody test is a blood test that detects IgA antibodies against endomysium, a connective tissue in the intestine. This test supports the diagnosis of celiac disease, an autoimmune condition triggered by gluten consumption.

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Understanding Endomysial - IgG antibody

Endomysial antibodies or anti-endomysial antibodies (EMA) are special proteins made by the immune system when there is ongoing damage in the lining of the small intestine. In people with celiac disease, eating gluten (a protein found in wheat, rye, and barley) triggers the immune system to mistakenly attack the endomysium, a thin layer of tissue around muscle fibers. This reaction causes inflammation and damage in the small intestine. This leads to poor absorption of nutrients and symptoms such as diarrhea, bloating, stomach pain, tiredness, weight loss, joint pain, or skin rash (called dermatitis herpetiformis). The Endomysial - IgG antibody test is one of the most specific tests used in celiac disease evaluation.

Doctors may recommend the Endomysial - IgG antibody test if there are symptoms of celiac disease, such as chronic diarrhea, abdominal bloating, unexplained weight loss, anemia, fatigue, or growth problems in children. This test is also used to confirm celiac disease in patients who have already tested positive for tTG IgA. In addition, the Endomysial - IgG antibody test can help monitor adherence to a gluten-free diet, since antibody levels usually decrease when gluten is eliminated. The test is also valuable in detecting IgA-endomysial antibodies in conditions like celiac disease and dermatitis herpetiformis, a skin disorder linked to gluten sensitivity.

No special preparation is required for the Endomysial - IgG antibody test. However, continue eating a diet that includes gluten for a few weeks before the test, unless the doctor advises otherwise. This is important because gluten-free diets may cause false negatives. Also, inform the doctor about all the medications and supplements currently being taken, as these may affect the test results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate and always consult a doctor to understand the test results correctly. 

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does Endomysial - IgG antibody measure?

The Endomysial - IgG antibody test measures the presence of IgA antibodies against endomysium in the blood. High levels strongly suggest celiac disease(when consuming gluten); while decreasing levels after treatment indicate a good response to a gluten-free diet. EMA IgA shows high specificity for active celiac disease and dermatitis herpetiformis.

FAQs related to Endomysial - IgG antibody

This test is mainly used to help diagnose celiac disease and dermatitis herpetiformis linked to gluten sensitivity. It detects IgA antibodies that attack the intestinal lining when gluten is consumed.
No, fasting is not required. However, you should be on a gluten-containing diet at the time of testing for accurate results.
Doctors may recommend the test if you have symptoms like chronic diarrhea, bloating, stomach pain, unexplained weight loss, fatigue, anemia, or in children with growth problems. It may also be advised if you have malnutrition or a skin rash called dermatitis herpetiformis.
Gluten-free diets cause false negatives. Doctors may advise gluten challenge (few weeks) before retesting.
A positive result suggests that you may have celiac disease and your intestine is being damaged by gluten. Further testing, medical advice and clinical correlation are required for confirmation.
A negative result reduces the chance of celiac disease, but it does not completely rule it out. If you have IgA deficiency, your doctor may recommend alternative antibody tests.
No, the Endomysial - IgG antibody test is generally safe with minimal risks. However, you may feel slight discomfort during blood sample collection, but the chances of serious complications are extremely rare.
Celiac disease is an autoimmune disorder where the immune system reacts abnormally to gluten (a protein found in wheat, rye, and barley). This reaction damages the small intestine and affects nutrient absorption.
Gluten sensitivity, also called non-celiac gluten sensitivity, is a condition where people experience symptoms like bloating, stomach pain, or fatigue after eating gluten, but they do not have celiac disease or wheat allergy. Endomysial - IgG antibody test is not recommended for this diagnosis.
No, celiac disease is a lifelong condition. However, with proper management and a gluten-free diet, most people live healthy, symptom-free lives.
Dermatitis herpetiformis is a chronic, itchy skin rash made up of small blisters and bumps. It is strongly linked to celiac disease and gluten sensitivity. Even if you do not have obvious digestive symptoms, this skin condition often indicates gluten intolerance and usually improves with a gluten-free diet.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Content created by
Written by:
Dr. Lipika Khurana
PGDHHM, BDS
Reviewed by:
Dr. Swati Gupta (Anand)
MD Lab Medicine, MBBS
Want to know moreRead our editorial policy
Last Updated4th Feb 2026

Endomysial - IgG antibody test price for other cities

Price inBangaloreRs. 2219
Price inMumbaiRs. 2159
Price inGurgaonRs. 1969
Price inNew DelhiRs. 1969
Price inPuneRs. 2319

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Endomysial - IgG antibody